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Active clinical trials for "Alveolar Bone Loss"

Results 81-90 of 175

Manuka Honey as an Adjunct to Non-surgical Periodontal Therapy: Clinical Study

Periodontal DiseasesPeriodontal Pocket2 more

The goal of this split-mouth clinical trial is to evaluate the effects of Manuka honey applied into periodontal pockets after initial periodontal therapy (NSPT) in the treatment of stage 3 periodontitis. The main question it aims to answer is: • does the adjunct of Manuka honey improve the outcome of the non-surgical periodontal treatment. The intervention in this study was conducted in a split-mouth design, meaning that after completing the NSPT for each subject, Manuka honey was administered as an adjunct to the periodontal treatment in two randomly selected quadrants of the oral cavity around the teeth with a specially designed cannula. This was followed by oral hygiene instructions and training. The home-performed oral hygiene procedures were focused on interdental cleaning using dental floss and toothbrushing with regular fluoride-containing toothpaste. The subjects were also instructed not to use any form of oral antiseptic (e.g., chlorhexidine) or antibiotic during the follow-up period.

Completed8 enrollment criteria

Comparison Synthetic Hydroxyapatite and Inorganic Bovine Bone in Sinus Floor Elevation

Alveolar Bone Loss

This is set as prospective clinical trial to correlate histologically and radiologically the performance of four different bone grafts (synthetic hydroxyapatite alone, synthetic hydroxyapatite mixed with polylactic-polyglycolic acid, synthetic hydroxyapatite with i-PRF and inorganic bone graft) in the sinus floor elevation technique with lateral approach for the treatment of atrophic crests.

Completed15 enrollment criteria

Evaluation of OSSIX-Plus Resorbable Collagen Membranes for Alveolar Ridge Preservation Following...

Alveolar Bone LossLoss of Teeth Due to Extraction1 more

The purpose of this study is to evaluate clinically, histologically and radiographically the healing of extraction sockets covered with a resorbable collagen membrane (OSSIX-Plus) 12 weeks following exodontia.

Completed12 enrollment criteria

mp3 vs Apatos in Post-extractive Sockets

Alveolar Bone Loss

The primary aim of the present multicenter randomized controlled trial was to evaluate and compare the shortterm clinical and histological changes of extraction sockets after ridge preservation procedures with changes of extraction sockets that healed naturally. The secondary aim was to evaluate which, if any extraction socket characteristics could have affected tissue changes occurring at the augmented as well as naturally healed sites. Recruitment and enrollment of patients were performed from June 2011 to June 2012 in five university centers/private practice: University of Pisa; University of Murcia; University of Ancona; Private practice, Dr. Di Felice; University of Verona. Randomization: extraction sockets with spontaneous healing; extraction sockets grafted with pre-hydrated collagenated cortico-cancellous porcine bone, with a particle size between 600 and 1000 μm; extraction sockets grafted with cortical porcine bone, with a particle size between 600 and 1000 μm. Outcome Variables Complications Changes of ridge volume contour; Vertical bone changes; Buccal-Lingual Width; Histomorphometric parameters. Sample size was calculated comparing outcome data between grafted sockets versus non-grafted sockets. The primary parameter was the change in mid-buccal vertical height (0.7±1.4mm and 3.6±1.5mm, respectively, for the test and control groups) (Barone et al. 2008). Final sample size was increased to 30 subjects per group due to possible patient dropout events. Each center contributed according to the predetermined 1:1:1 ratio; the fresh extraction socket was considered the unit of randomization. Corrections for balancing the three experimental groups for confounding factors were not applied. A matrix elaborator performed all the analyses§§: multi-way analysis of variance (ANOVAn) was applied, then appropriate post hoc comparison tests were run; post hoc estimated effect sizes were calculated with a power of 0.9. The level of statistical significance was set at 0.05 for all analyses.

Completed10 enrollment criteria

A Feasibility Study for Growth Bone Vertically With Titanium Mesh and Allograft in Lower Posterior...

Alveolar Bone Loss

This study will involve placing donor bone into the back of lower jaw then covering with a newly designed titanium mesh. The mesh will then stay in the mouth for 4 months before it will be removed. Implants will be placed in the newly formed bone. The goal of this study is to test how well using a newly designed titanium mesh and bone particles can grow bone in the back of the lower jaw. The investigators are also checking if the newly formed bone will stay around implants that will have been in use for 12 months.

Completed15 enrollment criteria

Conventional and Ultrasonic Implant Site Preparation

Bone AtrophyAlveolar

multi center study with randomized controlled trial design, split mouth

Completed9 enrollment criteria

Comparison of Extra-short (4 mm) Implants Used as Distal Support of a Maxillary Full-arch Fixed...

Alveolar Bone Loss

Recently, 4 mm long implants with a standard diameter have been used for the restoration of the posterior edentulous mandible with favorable results. However, randomized clinical trials reporting the results from full-arch fixed dental prosthesis that included 4 mm long implants placed in the posterior regions of the maxilla have not been published yet. The aim of the present study will be to compare the survival and success rates of 4 mm implants used as distal support of a maxillary full-arch fixed dental prosthesis with standard (10 mm) implants placed in association with a bilateral sinus floor augmentation procedure

Completed27 enrollment criteria

Histological Outcome of the Use of Different Biomaterials for Fresh Socket Regeneration. A Split-mouth...

Alveolar Bone Loss

Purpose: The aim of this study was to analyze the quality of bone regeneration in fresh sockets using four different materials and at different times points. Materials and Methods: A split-mouth clinical trial was designed to evaluate the histological and histomorphometrical characteristics of fresh sockets from 30 patients. One socket per patient will healed spontaneously (control) and, at least, one fresh socket, will be grafted with platelet-rich growth factor (PRGF), PRGF+autologous bone, autologous bone or PRGF+demineralized freeze dried bone allograft (DFDBA). The day of the implant placement, biopsies will be taken at different time points divided into three assessment groups: short duration (2-4 months), intermediate duration (5-6 months) and long duration (7-12 months). The histologic findings will be assessed to quantify the trabeculae pattern, the degree of mineralization and the quality of bone regeneration.

Completed11 enrollment criteria

Histomorphometric and Tomographic Assessment on the Influence of the Placement of a Collagen Membrane...

Alveolar Bone Loss

the purpose of the study is to look for differences in dimensional variations of augmented maxillary sinuses with or without the placement of a collagen membrane subjacent the sinus mucosa.

Completed12 enrollment criteria

Tomographic and Histologic Assessment on the Influence of the Use of a Collagen Membrane to Protect...

Alveolar Bone LossAlveolar Bone Resorption

the aim of the present study was to evaluate the dimensional variation and osseointegration of mini-implants at augmented sinus with the antrostomy left unprotected or protected with a collagen membrane.

Completed12 enrollment criteria
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