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Active clinical trials for "Aortic Aneurysm"

Results 1-10 of 668

Early Feasibility Study of the RelayBranch Thoracic Stent-Graft System

Thoracic Aorta AneurysmAneurysm2 more

The purpose of this study is to conduct an early clinical evaluation of the Relay Branch System, which will provide initial insight into the clinical safety and function of the device. This Early Feasibility Study (EFS) will assess the safety and effectiveness of the device at the index procedure and at 30-day follow-up. The study will evaluate the delivery and deployment of the device, patency of branches and branch vessels, and exclusion of the aortic pathology. The data will help determine if modifications need to be made to the device, the procedural steps, operator technique, or the indications for use.

Recruiting46 enrollment criteria

Alpha-Ketoglutarate and Abdominal Aortic Aneurysm Progression and Rupture

Patients With an Abdominal Aortic Aneurysm of 39-49 mm in Diameter

The objective of this project is to define whether nutritional supplement (oral administration with alpha-ketoglutarate) capable of filling-up the citric acid cycle (anaplerotic therapy) can improve outcomes in patients with an abdominal aortic aneurysm of 39-49 mm in diameter on ultrasound imaging. Alpha-ketoglutarate is commonly used as a nutritional supplement specially by athletes to increase muscle strength. They can be mixed with formula or other foods. Subjects will be followed for up to 5 years.

Recruiting18 enrollment criteria

Safety and Efficacy of Endovascular Repair of Complex Aortic Pathology With Physician-modified Endovascular...

Abdominal Aortic AneurysmThoracoabdominal Aortic Aneurysm1 more

The primary objective of this study is to examine the safety and effectiveness of physician-modified endovascular grafts (PMEGs) for endovascular repair of complex aortic pathology in high-risk patients. The study is divided into three study arms based on the subject's aortic pathology: (1) Complex abdominal aortic aneurysm (AAA); (2) Thoracoabdominal aortic aneurysm; and (3) Aortic dissection.

Recruiting52 enrollment criteria

PMEG for Repair of Pararenal and Thoracoabdominal Aortic Aneurysm

Pararenal Aortic AneurysmThoracoabdominal Aortic Aneurysm

The primary objective is to evaluate the safety and effectiveness of surgeon modified endografts for the treatment of pararenal and thoracoabdominal aortic pathology in patients who are not candidate for traditional open repair due to comorbid issues and their anatomy is not amenable to commercially available endografts.

Recruiting29 enrollment criteria

ShOrt neCK AAA RAndomized Trial - ESAR and FEVAR: SOCRATES

Aortic AneurysmAbdominal

The aim of this randomized study is to compare the safety and performance of EndoVascular Aneurysm Repair with ESAR using Endurant + Heli-FX™ EndoAnchor™ system and FEVAR using customizable grafts from Cook (Zenith Fenestrated Graft) and Terumo (Fenestrated Anaconda Graft) for the treatment of aortic aneurysms with short aortic neck (4 to 15mm).

Recruiting27 enrollment criteria

JAGUAR Trial: ObJective Analysis to GaUge EVAR Outcomes Through Randomization

AAAAAA - Abdominal Aortic Aneurysm

Prospective, randomized, multi-center study designed to evaluate the outcomes of commercially available contemporary EVAR in a real-world population. Patients will be randomized into two device cohorts and compared across the primary endpoints. Patients will be followed procedurally to discharge, at 1, 6, 12 months and annually through to 5 years (total follow-up commitment).

Recruiting12 enrollment criteria

ACT Guided Heparinization During Open Abdominal Aortic Aneurysm Repair.

Abdominal Aortic AneurysmSurgery1 more

Aim of the ACTION-1 study is to determine whether ACT guided heparinization decreases thrombo-embolic complications (TEC) and mortality after elective open AAA surgery, without causing more bleeding complications.

Recruiting16 enrollment criteria

ANEUFIX for Endoleak Type II Repair

Abdominal Aortic AneurysmEndoleak

The study is non-randomized, multicenter international safety, performance and clinical benefit outcome assessment of ANEUFIX to treat patients with isolated type II endoleak in the presence of a growing AAA-sac following an EVAR procedure more than 6 months ago.

Recruiting19 enrollment criteria

Safety and Efficacy Study of WeFlow-JAAA Stent Graft System for Complex Abdominal Aortic Aneurysm(GREAT...

Juxtarenal Abdominal Aortic Aneurysm

A prospective, multi-center, objective performance criteria clinical trial to evaluate the safety and efficacy of WeFlow-JAAA stent graft system manufactured by Hangzhou Endonom Medtech Co., Ltd. for the complex abdominal aortic aneurysm.

Recruiting29 enrollment criteria

Endovascular Treatment of TAAA and Aortic Arch Aneurysms Using Fenestrated and Branched Stent Grafts...

Aortic AneurysmThoracoabdominal4 more

Prospective, nonrandomized, single-center, two-arm study to assess the feasibility and safety and to evaluate clinical outcomes of endovascular repair of complex aortic aneurysms (thoracoabdominal aortic aneurysms and aortic arch aneurysms) in patients at high risk for open surgery.

Recruiting121 enrollment criteria
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