
Preventing Weight Gain in African American Reproductive-Aged Women
Weight GainWomen's Health1 moreThe purpose of this research study is to evaluate the effect of a Facebook-delivered weight-gain prevention program versus a Facebook-delivered program with general women's health information.

Dissemination of a Weight Management Program Among US Veterans
Body WeightThis study is being conducted with the Veterans Affairs National Center for Health Promotion and Disease Prevention (VANCP), which is overseeing the current dissemination of MOVE! (Managing Overweight/Obesity for Veterans Everywhere), a national weight management program for veterans. It will be based at 10 local sites in the national network of VA medical settings and community-based outpatient clinics and will compare two different models for disseminating and implementing MOVE! using a randomized experimental design. One study arm will implement the MOVE* VETS! (Volunteer Education and Tailored Self-management and support) model that includes tailored newsletters and peer counseling MI calls and activities, and the other will receive the standard MOVE! program.

Alternate Day Fasting for Weight Loss, Weight Maintenance and Cardio-protection
Coronary Heart DiseaseObesity1 moreThe proposed research will demonstrate that alternate day modified fasting (ADMF) is a suitable alternative to daily calorie restriction (CR) for weight loss, weight maintenance, and heart disease prevention. Since many overweight and obese individuals find it difficult to adhere to daily CR, this diet option may improve adherence with these dietary restriction protocols. This, in turn, will allow a greater percent of the overweight and obese population to lose weight, maintain weight loss, and prevent future occurrences of coronary heart disease.

Vitamin A Supplementation for Extremely-Low-Birth-Weight Infants
InfantNewborn12 moreThis multi-site, randomized trial was conducted to determine the safety and effectiveness of a higher dose of vitamin A and determine if this would increase the rate of survival without bronchopulmonary dysplasia (BPD) and reduce the risk of sepsis. Infants with birth weights from 401-1000g and who were on mechanical ventilation or supplemental oxygen at 24-96 hours of age were enrolled. Subjects were randomized to either the Vitamin A or a control group. Infants in the Vitamin A group were given a dose of 5000 IU (0.1 ml) intramuscularly on Mondays, Wednesdays, and Fridays for four weeks. Control infants received a sham procedure rather than placebo injections.

Effect of Dietary Fat When Eaten With Fructose Versus Glucose
Body Weight ChangesThis study is designed to test the effects on liver fat of varying fat intake in the presence of fructose or glucose. We hypothesize that higher dietary fat when eaten with fructose as compared to glucose will increase the amount of hepatic lipid as measured by magnetic resonance spectroscopy.

Oral Contraceptive Efficacy and Body Weight
ContraceptionBody WeightThe purpose of the blood spot validation portion of the study is to test if measuring female hormone levels in the blood is as accurate through a finger stick, as it is by a blood draw from a vein. The purpose of the feasibility study is to evaluate ovulation occurrence in two populations of oral contraceptive users: heavier and lighter women.

Effectiveness Evaluation of Three Strategies of Promotion of Healthy Dietary and Physical Activity...
Body WeightNutrition Processes1 moreThe aim of this study is to compare the effectiveness of three public health intervention strategies to reduce weight excess and obesity prevalence among teenagers within the frame of a public health program aiming at promoting healthy eating and physical activity behaviors.

The Effect of Weight Loss on Serum Mannose-Binding Lectin(MBL) Levels
ObesityWeight LossHigh levels of mannose-binding lectin (MBL), an activator of a part of the immune system called the complement system, have been associated with increased mortality and risk of early signs of kidney damage in patients with type 2 diabetes. The effect of weight loss and changes in insulin resistance on MBL levels have been poorly elucidated. This study includes 36 nondiabetic obese subjects, who will receive a very low- calorie diet (VLCD) of 800 kcal/day for 8 weeks. Fasting blood samples will be obtained at baseline and after 8 weeks of VLCD and concentrations of MBL, glucose and insulin will be measured. Insulin resistance is assessed using the HOMA-IR method.

Ethnic Dance and Screen Time Reduction to Prevent Weight Gain in Latina Girls
ObesityOverweight1 moreA randomized controlled trial to test the efficacy of an after school ethnic dance program plus a culturally-tailored, home-based screen time reduction intervention to reduce weight gain (body mass index) among lower socioeconomic status, pre-adolescent Latina girls.

Body Weight Support in Spinal Cord Injury
Spinal Cord InjuryThe purpose of this study was to evaluate the effectiveness of body weight-supported treadmill (BWST) training on static balance impairment in adults with incomplete spinal cord injury (SCI) in chronic stage