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Active clinical trials for "Heart Diseases"

Results 391-400 of 3529

CAPTURER PMCF Study ( rEPIC04D )

Coronary Artery Disease (CAD)Ischemic Heart Disease

Multicenter, prospective, non-randomized, post-market clinical follow-up (PMCF) study to confirm and support the clinical safety and performance of CAPTURER to meet EU Medical Device regulation (MDR) requirements in all the CONSECUTIVE patients treated with CAPTURER .

Recruiting3 enrollment criteria

Navitian PMCF Study ( rEPIC04C )

Coronary Artery Disease (CAD)Ischemic Heart Disease

Multicenter, prospective, non-randomized, post-market clinical follow-up (PMCF) study to confirm and support the clinical safety and performance of Navitian to meet EU Medical Device regulation (MDR) requirements in all the CONSECUTIVE patients treated with Navitian.

Recruiting3 enrollment criteria

Utility of MRI With Doppler Ultrasound Gating for Advanced Fetal Monitoring

Congenital Heart Disease

We will test an ultrasound device that uses sound waves to detect the fetal heart beat, and use this device to tell the MRI scanner when to collect pictures of the fetal heart. This will help freeze motion of the fetal heart, to make MRI pictures sharper. This will be important for assessing human fetal heart disease, an active area of research at our institution.

Recruiting8 enrollment criteria

Valvular Heart Disease Registry Study in Second Affiliated Hospital of ZheJiang University

Valvular Heart Disease

We design a prospective, observational cohort study to provide contemporary information on the prevalence, characteristics, risk stratification,cost-effective ,treatments and prognosis of Chinese hospitalised adult patients with valvular heart disease.

Recruiting7 enrollment criteria

Physical Activity and Cognitive Development in Children

Congenital Heart DiseasesChildren

Compare physical activity and cognitive functions between children having cardiac surgery with an age-matched group of children undergoing non-cardiac surgery, as well as otherwise healthy siblings or best buddies (or age and gender-matched children if no siblings or best buddies available) before surgery and after surgery or six months following initial assessment. Determine the effects of a structured physical activity program for 6 months following surgery on cognitive functions and adaptive behavior in children following congenital cardiac surgery. Determine the effects of a structured physical activity program for 12 months following surgery on cognitive functions and adaptive behavior in children following congenital cardiac surgery. We will perform exploratory analysis to determine whether any effects of a 12-months structured physical activity program on cognitive functions and adaptive behavior persist beyond 12 months after cessation of the program.

Recruiting17 enrollment criteria

Studies of Neuregulin/ERBB Signaling in Human Heart

Heart DiseaseVascular Disease1 more

This study examines the role of the epidermal growth factor (EGF) receptor family and the EGF family of ligands in the regulation of non-myocytes isolated from the human heart.

Recruiting10 enrollment criteria

Carcinoid Heart Disease and Peptide Receptor Radiotargetted Therapy

Carcinoid Heart DiseaseCarcinoid Syndrome1 more

Randomised trial to assess progression of carcinoid heart disease in patients treated with Lutathera therapy compared to best supportive care.

Not yet recruiting18 enrollment criteria

Treatment Success With the CoolLoop Cryoablation System

Atrial FibrillationParoxysmal Atrial Fibrillation5 more

This clinical study evaluates the safety and efficacy of the treatment with the CoolLoop® cryoablation System (sclerotherapy of muscle tissue of the heart by freezing) in patients with atrial fibrillation (permanent atrial fibrillation excepted) over a follow-up period of 36 months. A further aim of this study is to evaluate the average duration of procedure and fluoroscopy times.

Recruiting12 enrollment criteria

Multicenter Registry Study of Aortic Valve Stenosis in Zhejiang Elderly(Mrs AVS)

Valvular Heart Disease

Aortic valve stenosis (AVS) is becoming more and more frequent with the aging, which has brought a heavy burden to the world. However, the prevalence and prognosis of valvular heart disease are not so clear, especially in the developing countries such as China etc. Because of the slow and progressive nature of AVS, symptoms might not be too severe to be diagnosed on time. Our retrospective survey (Int J Cardiol. 2016 Nov 25) indicated that severe aortic valve stenosis are very common in China. Hence, we design a prospective, observational cohort study to provide contemporary information on the prevalence, characteristics, risk stratification,cost-effective ,treatments and prognosis of Chinese elderly patients with aortic valve stenosis.

Recruiting4 enrollment criteria

Erector Spinae Plane Block in Congenital Heart Disease Patients

Congenital Heart Disease in ChildrenNeurologic Complication

Pediatric cardiac patients undergoing surgical anesthesia are at an increased risk of poor neurologic outcome (20-50%). Unattenuated anesthetic exposure and pain contributes to physiologic perturbations that may increase neurologic morbidity. Because of the often-large exposure to anesthetic agents in these cardiac children, at such a young age and the potential modifying anesthetic practice that could lead to improved neurodevelopmental outcomes and surgical recovery is paramount. Regional anesthesia such as thoracic epidurals provide effective analgesia and reduced intraoperative anesthetic needed but carry devastating sequelae neurological risks of epidural hematomas after anticoagulation during cardiopulmonary bypass (CPB). Recently, a newly described erector spinae plane block (ESPB) is superficial to neuraxial or vascular structures, providing opportunity to be placed with less risk for surgery requiring CPB. This block has been described as effective regional anesthesia for adult cardiac surgery.

Not yet recruiting5 enrollment criteria
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