Mobility and Physical Activity in Adolescent and Young Adult Cancer Patients or Survivors at Risk...
Central Nervous System NeoplasmHodgkin Lymphoma3 moreThis study attempts to learn more about the activity levels of adolescent and young adult (AYA) cancer patients or survivors at risk for cardiovascular morbidity and frailty by using a smartphone application called Beiwe. Collecting activity level data on AYA cancer patients or survivors may help patients achieve better quality of life.
Studying Cerebrospinal Fluid Proteins and Angiogenesis Proteins in Young Patients With Newly Diagnosed...
Brain and Central Nervous System TumorsRATIONALE: Studying samples of cerebrospinal fluid from patients with cancer in the laboratory may help doctors identify biomarkers related to cancer. PURPOSE: This laboratory study is studying cerebrospinal fluid proteins and angiogenesis proteins in young patients with newly diagnosed central nervous system tumors.
Perceptions of Burden in Patients With Late-Stage Cancer and Their Caregivers
Brain and Central Nervous System TumorsChronic Myeloproliferative Disorders9 moreRATIONALE: Gathering information over time about patients' sense of being a burden on their caregiver, and caregivers' sense of burden on themselves, may help doctors learn more about the desire to die in patients with late-stage cancer. PURPOSE: This clinical trial is studying perceptions of burden in patients with late-stage cancer and their caregivers.
Collecting and Storing Blood Samples From Patients With Cancer
Brain and Central Nervous System TumorsChronic Myeloproliferative Disorders11 moreRATIONALE: Collecting and storing samples of blood from patients with cancer to test in the laboratory may help the study of cancer in the future. PURPOSE: This research study is collecting and storing blood samples from patients with cancer.
Cardiovascular Disorders and Risk Factors in Childhood Cranial and Craniospinal Tumors Survivors...
Tumors of the Central Nervous SystemChildhood Cancer SurvivorsThe purpose of research is to study to adverse cardiovascular disorder and risks factors in childhood cranial and craniospinal tumors survivors. In this research the investigators investigate cardiological instrumental diagnostic, such as electrocardiography, echocardiography with the determination of global longitudinal strain, cardiopulmonary exercise test, and diagnostic of endothelial function by Angioscan for the prediction of cardiovascular complications after cranial and craniospinal radiotherapy and chemotherapy.
Retrospective Study of MRI in Pediatric Patients
Central Nervous System DiseaseCentral Nervous System NeoplasmsCollection of already existing data and images for patients < 2 years of age having MultiHance administration for a MRI of the brain or spine. MR Images will be reviewed during a prospectively designed blinded reading of the images.
Coproporphyrine Isomers and Methotrexate Elimination
Central Nervous System NeoplasmsLymphoma4 moreHigh dose methotrexate (MTX) is responsible of severe toxicity in patients in whom elimination from plasma is delayed. Factors responsible for MTX accumulation are partly known but some patients still experience toxicity despite adequate measures being taken. Our hypothesis is that renal tubular secretion may be impaired in these patients. This study aims at evaluating the performance of the UCP ratio (urinary ratio of coproporphyrins), a putative biomarker of tubular secretion, in predicting delayed MTX elimination.
Diagnostic Efficiency of Artificial Intelligence for Surgical Neuropathology
Central Nervous System NeoplasmsThis is a multi-center, prospective, self-controlled, diagnostic accuracy comparative study of Artificial Intelligence Diagnostic System for Surgical Neuropathology. The investigators will compare the diagnostic efficiency of Artificial Intelligence with that of practicing pathologists, and suppose that the diagnostic efficiency of artificial intelligence in prospective clinical data is no less than that of pathologists.
Quality of Life in Patients Who Have Undergone Previous Treatment for Primitive Neuroectodermal...
Brain and Central Nervous System TumorsCognitive/Functional Effects2 moreRATIONALE: Questionnaires that measure quality of life may improve the ability to plan treatment for patients with primitive neuroectodermal tumors. PURPOSE: This phase III trial is studying quality of life in patients who have undergone previous treatment for primitive neuroectodermal tumors.
Study of Genes and Environment in Patients With Cancer in East Anglia, Trent, or West Midlands Regions...
Bladder CancerBrain and Central Nervous System Tumors7 moreRATIONALE: Studying samples of blood from patients with cancer in the laboratory may help doctors learn more about changes that occur in DNA and identify biomarkers related to cancer. PURPOSE: This study is looking at genetic susceptibility to cancer and interactions between genes and the environment in patients with cancer in East Anglia, Trent, or West Midlands of the United Kingdom.