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Active clinical trials for "Colitis, Ulcerative"

Results 91-100 of 1080

Fermented Food-Supplemented Diet in Ulcerative Colitis

Inflammatory Bowel DiseasesDiet Modification1 more

The purpose of this study is to see how a diet that supplements fermented foods effects inflammation and quality of life in patients with mild to moderate Ulcerative Colitis (UC). There is a paucity of research and an enormous need for better understanding of diet and intestinal inflammation. Fermented food have been shown to positively influence inflammatory cytokines and intestinal microbial diversity in healthy volunteers.

Recruiting14 enrollment criteria

Angiographic Delivery of AD-MSC for Ulcerative Colitis

Ulcerative Colitis

Researchers are trying to determine the safety and feasibility of using an adipose derived mesenchymal stem cell (MSC) to treat people with Ulcerative Colitis.

Recruiting30 enrollment criteria

A Study to Investigate the Efficacy and Safety of Dupilumab Therapy Compared With Placebo in Participants...

Colitis Ulcerative

The protocol of this Phase 2 clinical trial consists of a double-blind, placebo-controlled, parallel-group, multicenter study to evaluate the efficacy and safety of dupilumab in participants with moderately to severely active Ulcerative Colitis (UC) with an eosinophilic phenotype. Screening period: 2 to 4 weeks Treatment period: 52-week investigational medicinal product (IMP) intervention (dupilumab or matching placebo) from Week 0 to Week 52 Follow-up period: 12 weeks The maximum duration of study per participant is up to 68 weeks.

Recruiting22 enrollment criteria

Investigation of the Effects of Curcumin and Resveratrol Supplements Added to the Mediterranean...

Ulcerative Colitis

The aim of the study was to examine and compare the effects of Mediterranean diet, curcumin supplementation with Mediterranean diet in individuals with ulcerative colitis, and resveratrol supplementation with Mediterranean diet in individuals with ulcerative colitis, on disease symptoms, quality of life, and inflammatory biomarkers.

Recruiting12 enrollment criteria

ChAracterizing the Remission Status in Patients With Ulcerative Colitis Treated by 5-ASA

Ulcerative Colitis

For the last years the aim of the management of ulcerative colitis (UC) has become more ambitious including not only clinical remission but also the achievement of biological remission, endoscopic and histological healing, which are associated with less flares, hospitalizations and surgeries. About 50% of the patients with UC followed in routine are treated by 5-aminosalicylate acid (5-ASA) (oral and/or topical). The aim of the study is to describe the different levels of remission (clinical, endoscopic, histological) in UC patients treated only by 5-ASA, that report to be in clinical remission during a routine follow-up visit. The factors associated with different levels of remission (demographic, 5-ASA regimen, biologic, endoscopic, histologic) will be studied. Adherence and quality of life will be examined through patient questionnaires.

Recruiting15 enrollment criteria

Broccoli Sprouts for Mild Ulcerative Colitis

Ulcerative ColitisUlcerative Colitis Chronic Mild

The goal of this study is to determine the number of servings of broccoli sprouts sufficient to (1) increase sulforaphane levels in the stool and blood and (2) reduce inflammatory markers in patients with mild ulcerative colitis. This is a pilot feasibility study to prepare for a larger randomized controlled trial.

Recruiting16 enrollment criteria

A Study of Guselkumab Therapy in Participants With Moderately to Severely Active Ulcerative Colitis...

ColitisUlcerative

The purpose of this study is to evaluate the efficacy, including clinical remission of guselkumab subcutaneous (SC) induction compared to placebo in participants with moderately to severely active ulcerative colitis (UC).

Recruiting10 enrollment criteria

A Study to Learn About the Safety, Effects and Pharmacokinetics of Study Medication (PF-07054894)...

Ulcerative Colitis

This is a study to learn if the experimental medicine (called PF-07054894) is safe, effective, and how it is processed in adult people with ulcers in the colon.

Recruiting10 enrollment criteria

the Efficacy and Safety of Diosmin in Patients With Ulcerative Colitis

Ulcerative Colitis

This is a randomized, controlled study evaluating diosmin tablets administered daily for 3 months. The purpose of the study is to evaluate the efficacy and safety of diosmin in the treatment of mild to moderately active ulcerative colitis. Disease activity will be measured using modified truelove and witt's classification.

Recruiting13 enrollment criteria

A Study to Evaluate IBI112 in the Treatment of Moderate to Severe Active Ulcerative Colitis

Ulcerative Colitis (UC)

To evaluate the efficacy of IBI112 induction therapy in patients with moderate and severe active Ulcerative Colitis (UC) to achieve clinical remission.

Recruiting7 enrollment criteria
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