Clopidogrel Resistance and the Possibility of Its Affection
Coronary Artery DiseaseThe purpose of the study is to determine, whether the resistance to clopidogrel could be affected by higher doses of this drug, or by replacement of clopidogrel with another ADP-antagonist ticlopidine.
Resistance on Antithrombotic Drugs in Ischemic Heart Disease
Coronary Artery DiseaseThe purpose of this study is to determine whether aspirin and clopidogrel resistance measured with Multiplate function analyser has a good correlation with incidence of major adverse cardiac events in patients with coronary artery disease (CAD).
Contrast-Enhanced Whole-Heart Coronary Magnetic Resonance Angiography at 3.0-T: A Multicenter Trial...
Coronary Artery DiseaseThe multicenter study evaluates the diagnostic performance of 3.0 T contrast-enhanced whole-heart coronary MRA in patients with suspected coronary artery disease.
Strain-Encoded Cardiac Magnetic Resonance Imaging for Dobutamine Stress Testing
Coronary Artery DiseaseThe purpose of this study is to compare the diagnostic value of SENC to that provided by conventional wall motion analysis for the detection of inducible ischemia during DS-MRI.High-dose dobutamine stress magnetic resonance imaging (DS-MRI) is safe and feasible for the diagnosis of coronary artery disease (CAD) in humans. However, the assessment of cine scans relies on the visual interpretation of regional wall motion, which is subjective. Recently, Strain-Encoded MRI (SENC) has been proposed for the direct color-coded visualization of myocardial strain.
Genotype Information and Functional Testing Study
Coronary Artery DiseaseThis study is a sub-study of GRAVITAS (clinicaltrials.gov identifier NCT00645918). The purpose of this study is to assess which genes influence residual platelet reactivity on standard dose clopidogrel therapy, and also to determine whether certain genes influence the incremental change in platelet reactivity with high-dose clopidogrel maintenance dosing in patients who have high residual platelet reactivity on standard dosing.
Adenosine Dual Source Computed Tomography (CT) Versus Adenosine Single Photon Emission Computed...
Coronary Artery DiseaseResearchers hope that this new non-invasive multi-detector scanner (DSCT) will provide diagnostic information comparable to the combination of traditional SPECT (for function and blood flow) and CT imaging (for a precise anatomical view).
Vascular Inflammation in Adolescents With Type 1 Diabetes
Type 1 Diabetes MellitusCoronary Artery DiseaseThe purpose of this study is to find out if diabetes damages the blood vessels of adolescents with good diabetes control compared to adolescents with less optimal control.
Same Day Discharge After Coronary Stenting Trial
Coronary Artery DiseaseIn comparison to delayed hospital discharge, a strategy of early hospital discharge of patients who undergo single and multivessel stenting for type A, B, and C lesion(s) using thienopyridine and a hemostatic femoral closure device, is associated with similar clinical outcomes, but greater patient satisfaction and similar cost.
Discovery of New Circulating Biomarkers of Coronary Atherosclerosis
Coronary Artery DiseaseAcute Coronary Syndromes2 moreThe study hypothesis is that differential proteomic techniques can be used to discover new circulating biomarkers of coronary atherosclerosis in the blood of patients suffering from coronary artery disease (either stable or unstable) who will be compared to a group of patients without coronary artery disease
T Wave Alternans in Hemodialysis
End Stage Renal DiseaseCoronary Heart Disease1 moreThe purpose of this study is to determine if the hemodialysis procedure changes the risk for cardiac arrest in patients.