
Precision Medicine in Anesthesia
Respiratory DepressionThis study is designed to look at how often a decrease in the rate of breathing occurs after being given a routinely used intravenous (IV) pain medication. This pain medication (Fentanyl) is given in the research procedure room by the anesthesiologist. In addition to relieving pain, in some patients it has been observed that this medication may decrease the rate of breathing. Different pieces of one's genetic makeup (also known as genes) can affect how well this medication relieves pain. The investigators do not know if these same genes influence how large the effect of the medication has on breathing rate. The purpose of this study is to determine if the presence or alteration of these same genes may be associated with a decrease in rate of breathing.

A Study to Assess the Efficacy and Safety of REL-1017 as Monotherapy for Major Depressive Disorder...
Major Depressive DisorderThis is an outpatient, 2-arm, Phase 3, multicenter, randomized, double-blind, placebo-controlled study to assess the efficacy and safety of REL-1017 once daily (QD) as a monotherapy for Major Depressive Disorder.

Asynchronous Techniques for the Delivery of Empirically Supported Psychotherapies
Depressive SymptomsAnxiety2 moreThe aim of this study is to test the feasibility, acceptability and efficacy of methods for delivering mental health support when real-time communication is not possible (e.g. on long duration space flights where communication lags of up to 45 minutes are anticipated). The investigators hypothesize that the two enhanced treatment conditions (i.e., those with therapist support) will outperform the online self-management program without support. The investigators also predict that outcomes for the two enhanced conditions will be comparable to those reported in the literature for in-person psychotherapy programs.

Digital Therapeutic vs Psychoeducation for Management of Mild to Moderate Depression in Adolescents...
DepressionTeenThe purpose of the present randomized controlled study is to investigate if there is a difference in depression symptoms at 4-weeks among adolescents ages 16-17 years assigned to W-GenZD, a digital therapeutic, as compared to a psychoeducational control group.

Assessing Effectiveness of ThoughtFullChat Application in Improving Mental Well-Being
AnxietyDepression2 moreTo determine the state of mental health among house officers, IMU corporate staff, IMU students and IMU faculty To find out the effectiveness and user experience of text-based mental health coaching applications among house officers, IMU corporate staff, IMU students and IMU faculty IMU - International Medical University

Effect of Yoga on Postpartum Depression
YogaThis study was conducted to investigate the effect of yoga on postpartum depression. Subjects: Forty primipara women with postpartum depression (PPD) selected randomly from Kasr El Ainy University Hospital in Cairo complaining of postpartum depression at least one month after childbirth shared in this study.

Efficacy of Edupression.Com® in Depressive Patients
Depressive; EpisodeMajor4 moreThe aim of the study is to investigate the efficacy and adherence of the digital self-help programme edupression.com®.

Feasibility of a Novel Process-based Treatment for Patients With Psychosis
SchizophreniaSchizotypal Disorder20 moreThe purpose of this single-arm feasibility study is to develop and pilot test a novel process-based and modular group therapy approach for patients with acute psychotic symptoms in an inpatient setting.

Evaluation of the Efficacy of Internal Family Systems (IFS) Therapy
PTSDDepressionStudy examining the effectiveness of 16 weeks of Internal Family Systems (IFS) therapy for adults with posttraumatic stress disorder (PTSD).

Abdominal Breathing for Depression, Anxiety, Heart Rate Variability in Obstructive Sleep Apnea Patients...
Obstructive Sleep ApneaThe research topic is to explore the effectiveness of abdominal breathing on improving of depression, anxiety, and heart rate variability in obstructive sleep apnea patients with depressive symptoms. This study method adopts an experimental research design and divided into experimental group and control group by random sampling. Experimental group receives abdominal breathing training, whereas control group without receiving abdominal breathing training.