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Active clinical trials for "Diabetes Mellitus"

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Safety Study of Using Symlin Alongside Insulin in a Multiple Injection Port

Type 1 DiabetesType 2 Diabetes

The purpose of this study is to determine whether injecting Symlin and insulin through a multiple injection port is safe and effective. This will be measured by HbA1c values taken at the beginning of the study and at the final visit. The secondary objective of the study is to measure patient satisfaction toward using the multiple injection port.

Terminated18 enrollment criteria

Using Sitagliptin as a Treatment to Prevent New Onset Diabetes After Kidney Transplantation

Type 2 DiabetesEnd Stage Renal Disease

This study is designed to see if the use of the drug Sitagliptin (used to reduce insulin resistance) will delay or prevent kidney transplant patients from getting diabetes.

Terminated6 enrollment criteria

Effectiveness and Safety of Two Approaches to the Management of Type 2 Diabetes Mellitus in Australian...

Diabetes MellitusType 2

The primary objective is to demonstrate the improvement in glycosylated haemoglobin (HbA1c) levels after general practitioner (GP) initiation and management of type 2 diabetes mellitus (T2DM) with insulin glargine compared with their usual clinical practice. The secondary objective is to demonstrate the importance of GP initiation of insulin glargine for the treatment of T2DM.

Terminated28 enrollment criteria

Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of Oral Insulin (IN-105) in Type 1 Diabetes...

Type 1 Diabetes Mellitus

The purpose of this study is to see whether IN-105 (oral insulin) is able to control increase in blood glucose after eating a meal. This study will also tell whether single tablet of IN-105 is safe for patients with Type 1 diabetes mellitus who are currently taking insulin injections.

Terminated24 enrollment criteria

Efficacy and Safety of TAK-379 in Adult Subjects With Type 2 Diabetes Mellitus

Diabetes Mellitus

The purpose of this study is to evaluate the safety and effectiveness of multiple doses of TAK-379, once daily (QD), in subjects with type 2 diabetes mellitus.

Terminated46 enrollment criteria

Safety and Efficacy of TAK-559 in Combination With Metformin in Patients With Type 2 Diabetes Mellitus....

Diabetes Mellitus

The purpose of this study is to evaluate the safety and efficacy of TAK-559, once daily (QD), taken in combination with metformin in treating subjects with type 2 diabetes mellitus

Terminated42 enrollment criteria

Intravenous Insulin in Patients With Diabetes After Percutaneous Coronary Intervention (PCI)

Diabetes MellitusPercutaneous Coronary Intervention

The purpose of this study is to evaluate the effects of intravenous insulin/24 hours to normalize glycemia upon markers of oxidative stress (protein oxidation and total antioxidant defense) and inflammation (C-reactive protein (CRP) and sCD40L) in diabetic patients submitted to PCI with stent.

Terminated7 enrollment criteria

Safety and Efficacy of Dutogliptin in Patients With Type 2 Diabetes Mellitus (T2DM) on Background...

Diabetes MellitusType II

This study will evaluate the safety and efficacy of dutogliptin in patients with type 2 diabetes mellitus (T2DM) who are receiving background therapy of glimepiride with or without metformin.

Terminated6 enrollment criteria

GALLEX 1 - Long Term Extension Study in Patients With Type 2 Diabetes

Type 2 Diabetes

This is a 107-week open-label, multi-center long-term extension study from GALLANT studies 2/22, 5, 7, 8 and 14 to monitor the safety and tolerability of oral tesaglitazar 1 mg in patients with type 2 diabetes during up to 104 weeks of treatment. The total duration, including treatment and follow-up, is 107 weeks.

Terminated13 enrollment criteria

Clinical Effects of Pulsatile Insulin Delivery on Cognitive Function- Phase 1

Diabetes Mellitus

To determine if restoring normal metabolic function in patients with either Type I or Type II Diabetes can improve overall cognitive function. Patients are treated once a week with pulsatile intravenous insulin therapy mimicking normal insulin secretion and high amounts of oral glucose consumption.

Terminated14 enrollment criteria
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