
Efficacy of Changing to TRAVATAN® From Prior Therapy
Open-angle GlaucomaOcular HypertensionThe purpose of this study was to assess the efficacy and tolerability of TRAVATAN® solution without BAK (benzalkonium chloride) after changing from prior latanoprost 0.005% ophthalmic solution monotherapy in subjects with open-angle glaucoma or ocular hypertension due to tolerability issues.

Assessment of Intraocular Pressure (IOP) Control in Subjects With Open-Angle Glaucoma or Ocular...
GlaucomaOcular Hypertension1 moreThe purpose of this study was to assess efficacy and tolerability of travoprost 0.004% vs. bimatoprost 0.01% during the after office hour period (4 pm to 8 pm) in subjects with open-angle glaucoma or ocular hypertension after 6 weeks of treatment.

Multicenter Investigation of the Glaukos® Suprachoroidal Stent Model G3 In Conjunction With Cataract...
Primary Open-angle GlaucomaEvaluate the safety and efficacy of the Glaukos® Suprachoroidal Stent Model G3 in conjunction with cataract surgery, compared to cataract surgery only, in subjects with mild to moderate primary open-angle glaucoma.

NT-501 CNTF Implant for Glaucoma: Safety, Neuroprotection and Neuroenhancement
GlaucomaPrimary Open AngleCiliary Neurotrophic Factor (CNTF) has been demonstrated in multiple pre-clinical models to enhance survival and regeneration of retinal ganglion cells, the retinal neurons injured in diseases like glaucoma. We hypothesize that CNTF delivery to the human eye will provide neuroprotection (prevent loss of vision) and neuroenhancement (improve vision indices) in glaucoma. Patients in the trial will receive an NT-501 CNTF implant (made by Neurotech) into one eye, and will be carefully followed to evaluate safety and efficacy.

Bimatoprost/Timolol Versus Travoprost/Timolol
GlaucomaThe purpose of this study is to compare 2 fixed combination medications in intraocular pressure lowering.

A Phase 1/2 Multicenter, Randomized, Study to Evaluate the Safety and Efficacy of VS101 Subconjunctival...
Open Angle GlaucomaOcular HypertensionSlow release formulation of latanoprost is compared for safety and pressure-lowering efficacy with topically administration of commercially available latanoprost in patient with glaucoma and ocular hypertension

An Open-Label Extension Study to Evaluate the Safety of the ForSight VISION5 Product
Primary Open-Angle GlaucomaOcular HypertensionThis study evaluates the long-term (13-months) safety of the Bimatoprost Ocular Insert in participants with Glaucoma or Ocular Hypertension who completed study FSV5-002. All participants received Bimatoprost Ocular Insert and wore it for approximately 7 months, then had the Insert removed and a new insert placed for another 6 months.

Efficacy and Safety of Bimatoprost Sustained-Release (SR) in Patients With Open-Angle Glaucoma or...
GlaucomaOpen-Angle1 moreThis study will evaluate the efficacy and safety of bimatoprost sustained-release (SR) in patients with open-angle glaucoma or ocular hypertension. The study includes a 12-month treatment period with an 8-month extended follow-up.

Transconjunctival Needling Revision Versus Medical Treatment
Primary Open Angle GlaucomaWhen the glaucoma filtering surgery failures (intraocular pressure rises again), the options is start to use the hypotensive eye drops again (medical treatment). However, in some cases (encapsulated blebs), there is a simple surgical revision that can revival the primary failure surgery. It calls transconjunctival needling revision. In this study, the investigators compare the efficacy of this revision versus medical treatment in 12-month follow up in eyes with encapsulated blebs.

Multi-center Study Assessing the Safety and Efficacy of DE-117 Ophthalmic Solution in Subjects With...
Open-angle Glaucoma or Ocular HypertensionThe purpose of this study is to investigate the safety and efficacy of four concentrations of DE-117 ophthalmic solution.