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Active clinical trials for "Glaucoma"

Results 451-460 of 1636

Efficacy of Changing to TRAVATAN® From Prior Therapy

Open-angle GlaucomaOcular Hypertension

The purpose of this study was to assess the efficacy and tolerability of TRAVATAN® solution without BAK (benzalkonium chloride) after changing from prior latanoprost 0.005% ophthalmic solution monotherapy in subjects with open-angle glaucoma or ocular hypertension due to tolerability issues.

Completed21 enrollment criteria

Assessment of Intraocular Pressure (IOP) Control in Subjects With Open-Angle Glaucoma or Ocular...

GlaucomaOcular Hypertension1 more

The purpose of this study was to assess efficacy and tolerability of travoprost 0.004% vs. bimatoprost 0.01% during the after office hour period (4 pm to 8 pm) in subjects with open-angle glaucoma or ocular hypertension after 6 weeks of treatment.

Completed20 enrollment criteria

Multicenter Investigation of the Glaukos® Suprachoroidal Stent Model G3 In Conjunction With Cataract...

Primary Open-angle Glaucoma

Evaluate the safety and efficacy of the Glaukos® Suprachoroidal Stent Model G3 in conjunction with cataract surgery, compared to cataract surgery only, in subjects with mild to moderate primary open-angle glaucoma.

Completed5 enrollment criteria

NT-501 CNTF Implant for Glaucoma: Safety, Neuroprotection and Neuroenhancement

GlaucomaPrimary Open Angle

Ciliary Neurotrophic Factor (CNTF) has been demonstrated in multiple pre-clinical models to enhance survival and regeneration of retinal ganglion cells, the retinal neurons injured in diseases like glaucoma. We hypothesize that CNTF delivery to the human eye will provide neuroprotection (prevent loss of vision) and neuroenhancement (improve vision indices) in glaucoma. Patients in the trial will receive an NT-501 CNTF implant (made by Neurotech) into one eye, and will be carefully followed to evaluate safety and efficacy.

Completed10 enrollment criteria

Bimatoprost/Timolol Versus Travoprost/Timolol

Glaucoma

The purpose of this study is to compare 2 fixed combination medications in intraocular pressure lowering.

Completed2 enrollment criteria

A Phase 1/2 Multicenter, Randomized, Study to Evaluate the Safety and Efficacy of VS101 Subconjunctival...

Open Angle GlaucomaOcular Hypertension

Slow release formulation of latanoprost is compared for safety and pressure-lowering efficacy with topically administration of commercially available latanoprost in patient with glaucoma and ocular hypertension

Completed4 enrollment criteria

An Open-Label Extension Study to Evaluate the Safety of the ForSight VISION5 Product

Primary Open-Angle GlaucomaOcular Hypertension

This study evaluates the long-term (13-months) safety of the Bimatoprost Ocular Insert in participants with Glaucoma or Ocular Hypertension who completed study FSV5-002. All participants received Bimatoprost Ocular Insert and wore it for approximately 7 months, then had the Insert removed and a new insert placed for another 6 months.

Completed6 enrollment criteria

Efficacy and Safety of Bimatoprost Sustained-Release (SR) in Patients With Open-Angle Glaucoma or...

GlaucomaOpen-Angle1 more

This study will evaluate the efficacy and safety of bimatoprost sustained-release (SR) in patients with open-angle glaucoma or ocular hypertension. The study includes a 12-month treatment period with an 8-month extended follow-up.

Completed5 enrollment criteria

Transconjunctival Needling Revision Versus Medical Treatment

Primary Open Angle Glaucoma

When the glaucoma filtering surgery failures (intraocular pressure rises again), the options is start to use the hypotensive eye drops again (medical treatment). However, in some cases (encapsulated blebs), there is a simple surgical revision that can revival the primary failure surgery. It calls transconjunctival needling revision. In this study, the investigators compare the efficacy of this revision versus medical treatment in 12-month follow up in eyes with encapsulated blebs.

Completed2 enrollment criteria

Multi-center Study Assessing the Safety and Efficacy of DE-117 Ophthalmic Solution in Subjects With...

Open-angle Glaucoma or Ocular Hypertension

The purpose of this study is to investigate the safety and efficacy of four concentrations of DE-117 ophthalmic solution.

Completed17 enrollment criteria
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