AR-12286 Fixed Dose Combination to Lower Elevated Intraocular Pressure
GlaucomaOcular HypertensionThis is a double-masked, randomized, controlled study assessing the safety and ocular hypotensive efficacy of two AR 12286/travoprost fixed-dose combination products compared to Travatan® Z in patients with elevated intraocular pressure
A Dose Evaluation Study of the Effect of Plug Placement on the Efficacy and Safety of the Latanoprost...
GlaucomaOcular Hypertension (OH)The purpose of this study is to determine the effect of plug placement on the efficacy, safety and duration of effect of the L-PPDS (latanoprost punctal plug delivery system).
Subjects With Open-angle Glaucoma, Pseudoexfoliative Glaucoma, or Ocular Hypertension Naïve to Medical...
Open-angle GlaucomaEvaluation of the intraocular pressure (IOP) lowering effect of two iStent devices versus medical therapy in eyes of subjects with primary open-angle glaucoma, pseudoexfoliative glaucoma, or ocular hypertension naïve to medical and surgical therapy.
Multiple Dose-escalation Study of AMA0076 in Patients With Ocular Hypertension or Primary Open-angle...
GlaucomaOcular Hypertension1 moreThe objective of this dose-escalation study is to evaluate the safety, tolerability and efficacy of AMA0076 in reduction of intraocular pressure in subjects with ocular hypertension or primary open-angle glaucoma.
Safety and Efficacy of Different Formulations of Bimatoprost Ophthalmic Solution in Patients With...
GlaucomaOcular HypertensionThis study will evaluate the safety and efficacy of bimatoprost 0.03% formulation B ophthalmic solution with LUMIGAN® (bimatoprost ophthalmic solution 0.03%) once daily for 12 weeks in patients with glaucoma or ocular hypertension
A Study of Open Angle Glaucoma or Ocular Hypertension in Patients Within the United Kingdom
Ocular HypertensionOpen Angle GlaucomaStudy PhXA41 for its non-inferiority compared with timolol in lowering intra-ocular pressure
A 6 Month Study Comparing Latanoprost With Timolol in Patients With Open Angle Glaucoma or Ocular...
GlaucomaOpen Angle Glaucoma1 morePhXA41 is not inferior to timolol
Phase IV Randomised Double-masked Clinical Trial: Assessing Morning Versus Evening Dosing of a Fixed...
Open-angle GlaucomaOcular HypertensionThe purpose of this study is to assess the IOP-lowering efficacy of a combination of Travoprost / Timolol maleate, dosed in the morning or in the evening, in patients with open-angle glaucoma or ocular hypertension, who have an insufficiently controlled IOP (mmHg), and are using prostaglandin analogue monotherapy.
Phase 1-2 Evaluation of OT-730 Eye Drops in Reducing the Intraocular Pressure in Patients With Ocular...
GlaucomaOpen-Angle1 moreThe purpose of this study is to evaluate the safety and potential efficacy of a new drug, OT-730 ophthalmic solution (eye drops), in reducing intraocular pressure in the eyes of patients with open angle glaucoma or ocular hypertension. It will be compared with commercial timolol and placebo eye drops.
Oral Acetazolamide, Brimonidine Tartarate, and Anterior Chamber Paracentesis for Ocular Hypertension...
Age Related Macular DegenerationDiabetic RetinopathyThe purpose of this study is to evaluate the effects of anterior chamber paracentesis, brimonidine and oral acetazolamide to reduce intra-ocular pressure variations after intravitreal bevacizumab injection.