Effect of a Single Colecalciferol Dose on Insulin Resistance
Insulin ResistanceGlucose IntoleranceA Prospective Double-Blinded, Placebo Controlled, Randomized Trial comparing a single dose of Vitamin D (Colecalciferol) 300.00UI to placebo on patients with insulin resistance. Primary Outcome: Blood glucose and homeostasis model assessment for insulin resistance (HOMA-R) after 90 days. Study hypothesis: Vitamin D treatment may improve insulin resistance and decrease glucose level, since there is an association between hypovitaminosis D and increased insulin resistance.
Actos Now for Prevention of Diabetes (ACT NOW)
Impaired Glucose ToleranceType 2 DiabetesThe purpose of this study is to examine whether pioglitazone versus placebo can reduce the conversion rate of impaired glucose tolerance (IGT) to type 2 diabetes mellitus
Effective Endurance Training in Metabolic Syndrome
Impaired Glucose ToleranceOverweight2 moreTo see how fast and how much physical training can reduce risk factors related to metabolic syndrome
18F-FDOPA PET/CT Imaging in Patients Undergoing Metabolic Surgery
Diabetes MellitusType 22 moreThe aim of the study is to compare the endocrine function of pancreas between pre and post metabolic surgery in patients with type 2 diabetes or prediabetes. The study will examine the endocrine function of pancreas using 18F-FDOPA PET/CT imaging and various biochemical laboratory tests
Continuous Glucose Monitoring in Diabetes and Prediabetes
Diabetes MellitusType 22 moreEvaluate the use of brief serial real time continuous monitoring (RT-CGM) as a behavior modification tool in obese patients with prediabetes and diabetes. After receiving RT-CGM, nutrition and exercise education, participants will be able to monitor their blood sugar in real time for 2 sessions . Education on how to interpret CGM in the setting of food choices and exercise coupled with nutrition and exercise information should lead to improved weight and other nutritional and exercise changes.
Maternal Health Diabetes Prevention Study
Gestational DiabetesPreDiabetes2 moreThe aim of this project is to use the Exploration, Preparation, Implementation, Sustainment (EPIS) framework to collect pilot data on the implementation of a Diabetes Prevention Program-like intervention in the Women, Infants, and Children (WIC) program.
Evaluation of a Lifestyle Intervention for Employees With Prediabetes
PrediabetesOverweight1 moreThe purpose of this study is to evaluate the impact of a worksite lifestyle intervention for diabetes prevention among employees with prediabetes.
Multi-Channel Automated Diet and Physical Activity Intervention for Pre-Diabetics
Pre-diabetesDiabetes1 moreThe trial will test whether the Alive multi-channel delivery health behavior program can positively affect weight and glucose level in pre-diabetics.
Effects of Rosiglitazone on the Metabolic Phenotype of Impaired Glucose Tolerance in Youth
ObesityImpaired Glucose Tolerance1 moreThe purpose of the study is to determine whether treatment of children and adolescents with Impaired Glucose Tolerance (IGT) with rosiglitazone will lead to improvements in insulin sensitivity and glucose tolerance.
Impact of a Diabetes Risk Score on Lifestyle Education and Patient Adherence
Pre-diabetesDiabetes Risk Score1 moreThe purpose of this randomized, controlled study is to evaluate whether the knowledge of a personalized diabetes risk score affects adherence to a 12-week diet and exercise lifestyle change program in prediabetic patients. The intervention group will receive diabetes risk score results at the beginning of the twelve weeks, and the control group will not receive these results. Both groups will review their baseline and 12-week diabetes risk score results at the conclusion of the program and will be followed for an additional twelve weeks. Attendance rates and changes in weight, BMI, abdominal circumference, blood pressure, HgA1c, fasting blood glucose, cholesterol, and diabetes risk score will be compared between the groups.