Delafloxacin Versus Vancomycin and Aztreonam for the Treatment of Acute Bacterial Skin and Skin...
Skin and Subcutaneous Tissue Bacterial InfectionsThis study was designed to evaluate the efficacy of delafloxacin patients with acute bacterial skin and soft tissue infections (ABSSSI).
A Study to Assess the Relative Bioavailability of Three Formulations and Food Effect on GSK1322322...
InfectionsBacterialThis study is an open-label, randomized, single dose, four period, balanced crossover study to assess in eligible healthy male or female subjects.
A Study to Assess Objective Endpoint Measurements of Response in Bacterial Skin Infections
Skin and Subcutaneous Tissue Bacterial InfectionsThe purpose of this study is to compare clinical response to the measurement techniques of several objective measures of clinical efficacy for use in future ABSSSI (Acute Bacterial Skin and Skin Structure Infection) clinical trials
Efficacy and Safety Study of Finafloxacin Used in Helicobacter Pylori Infected Patients
Gram-Negative Bacterial InfectionsHelicobacter Infections1 moreThe primary objective of this study is to compare the H. pylori eradication rates with Finafloxacin in combination with Amoxicillin or Esomeprazole. The secondary objective is to evaluate and compare the safety and tolerability of multiple oral doses of Finafloxacin plus Amoxicillin versus Finafloxacin plus Esomeprazole.
A Safety and Tolerability Study of Doripenem in Patients With Abdominal Infections or Pneumonia...
PneumoniaVentilator-Associated5 moreThe purpose of this study is to assess the safety and tolerability of doripenem compared to imipenem in Ventilator-assisted pneumonia and complicated Intra-abdominal Infection. The study population will include hospitalized patients (or patients resident in a chronic health care facility) who have a diagnosis of either Ventilator associated pneumonia or complicated Intra-abdominal Infection.
Azithromycin Level in Tears and in Conjunctiva in 36 Healthy Volunteers
Eye InfectionsBacterialTo evaluate azithromycin ocular conjunctiva concentrations 7 and 14 days after treatment initiation. To assess ocular and systemic tolerance/safety and azithromycin tear concentrations on Day 7
Ocular Tolerance, Safety and Ocular Pharmacokinetics After 1 Drop of T1225 0.5, 1.0, 1.5% in 48...
Eye InfectionsBacterialTo compare the ocular tolerance, the safety and the ocular pharmacokinetics of 3 concentrations (0.5% - 1.0% - 1.5%) and the vehicle of T1225 after one drop instillation
Safety and Ocular Pharmacokinetics After 1 Drop of T1225 0.5, 1 and 1.5% in 48 Healthy Volunteers...
Eye InfectionsBacterialTo compare the ocular tolerance, safety and ocular pharmacokinetics of 3 concentrations (0.5% - 1.0% - 1.5%) and the vehicle of T1225.
Study of the Safety and Effectiveness of Rabeprazole in Treatment of Helicobacter Pylori Infection...
Helicobacter InfectionsBacterial InfectionsThe purpose of the study is to confirm the safety and effectiveness of rabeprazole in the treatment of adult patients with Helicobacter pylori (H. pylori) infection in routine clinical practice.
Topical SB-275833 Ointment, 1% For The Treatment Of Impetigo
Skin InfectionsBacterialThe goal of this study is to determine if topical SB-275833 ointment, 1% is as safe and effective as topical sodium fusidate ointment, 2% for the treatment of impetigo in adults and children as young as 9 months of age.