Provocative Testing Using LHRH and hCG of the Pituitary-Gonadal Axis in Persons With Spinal Cord...
HypogonadismSpinal Cord InjuryThere is evidence that has shown that serum testosterone levels are low in persons with chronic spinal cord injury (SCI). The question arises as to whether the defect in testosterone production is from the hypothalamic pituitary system (part of the brain that plays a role in testosterone release) or from the male testes. Studies to date are inconclusive. This study, will examine if persons with SCI has a normal hormonal regulation of the male hormone testosterone in comparison to persons who are able-bodied. This will help understand the physical and metabolic changes that occur in persons with SCI.
Measuring the Feasibility and the Effects of Chair Massage on Pain and Discomfort in the Cardiac...
Overuse InjuryRepetitive Strain InjuryThe purpose of this study is to determine whether the effects of chair massage and/or chair massage with stretching may reduce musculoskeletal pain and discomfort related symptoms associated with the job duties of a cardiac sonographer.
Magnesium Administration in Liver Transplantation and Reperfusion Injury
Living Donor Liver TransplantationReperfusion InjuryThe purpose of this study is to evaluate the effect of intravenous magnesium infusion before reperfusion with employing some clinical parameters including blood lactate levels, because the intraoperative changes in the blood lactate levels after hepatic allograft reperfusion served as an accurate predictor of the initial graft function in living donor liver transplantation.
Prophylactic Antibiotics for Prevention of Wound Complications Following Vulvectomy
Wound InfectionThis randomized prospective study will specifically investigate the efficacy of a 24 hour post-operative course of broad-spectrum prophylactic antibiotics - namely Cefazolin - in preventing wound infection and wound breakdown following vulvectomy.
Preventing Pneumonia and Other Respiratory Problems in Persons With Spinal Cord Injury
Spinal Cord InjuryIt is known that individuals with spinal cord injury are at increased risk for respiratory tract infections like pneumonia. Part of this risk is due to weakened chest and abdominal muscles that are vital to deep breathing and the ability to cough. The purpose of this study is to look at the effectiveness of two different treatments in preventing pneumonia and other respiratory problems in persons with SCI. This is a randomized controlled trial investigating the effectiveness of two different treatments. Participants will be randomly assigned to one of the two treatment groups. They will not be told the details of the other intervention since this could influence or change their activities during the study.
TETRAM 2. Treatment With Erythropoetin in Patients With Spinal Trauma With Neurological Deficit,...
Spinal Trauma With Neurological DeficitThe social, psychological, economic burden of Spinal trauma with deficit is great, and there is no curative treatment. Erythropoetin (EPO) is promising, due to its neuroprotective effects demonstrated in vitro, in vivo in animal models and in a preliminary study including patients with stroke. The study primary end point is to find out the maximum tolerated dose of EPO. This is based on the occurrence of pulmonary embolism during a 14 day delay following EPO injection. Secondary end points include comparisons of EPO kinetics in blood and cerebrospinal fluid (CSF), study of EPO effects on several inflammatory and apoptotic bio markers and blood cell counts. The experimental design is a dose scale study (600 to 2400 UI/Kg), using a single dose of rHuEPO, (EPREX®). The EPO dose is defined using a Bayesian continuous reassessment Method (CRM). The sample size is expected for less than 20 patients. Eligible patients are patients aged 15 to 65 years, able to receive the EPO injection within 12 hours of a spinal trauma, without vital blood loss or associated diseases. The follow-up lasts 6 months.
The Effect of Mild Traumatic Brain Injury on Recovery From Injury
Traumatic Brain InjuryTrauma2 moreMild traumatic brain injury (TBI) is a common injury that can produce significant functional sequelae and ongoing disabling symptoms. Predicting who will have an uncomplicated recovery and who will suffer ongoing symptoms is difficult. This protocol evaluates the use of neuropsychologic testing after mild TBI in injured patients to attempt to objectively establish predictors of long term disability and functional recovery.
Epidural Blood Patch on the Resolution of Postdural Puncture Headache (PDPH)
Post-Lumbar Puncture HeadacheThe purpose of this study is to address the question, "What is the volume of blood for injection at epidural blood patch that most effectively relieves post-dural puncture headache?"
Transcranial Doppler Measurement and Prognosis in Moderate Head Injury
Head InjuryThe purpose of this study is to determine whether Transcranial Doppler measurements have correlation with neuropsychological test (Galvestone Orientation Amnesia Test), TC image (Marshall Scale) and prognosis (DRS and GOS) in moderate head injury
Effectiveness of Glove Changing in Reducing Wound-related Complications
Wound ComplicationThis study aimed to investigate the effectiveness of glove changing in reducing complications of cesarean deliveries in Vietnam.