Incisional Negative Pressure Wound Therapy for Prevention of Postoperative Infections Following...
Surgical Wound InfectionInfection; Cesarean Section8 moreThe purpose of this study is to examine whether obese women (BMI >= 30) who give birth by caesarean section have a reduced incidence of wound infection and dehiscence when incisional Negative Pressure Wound Therapy is applied prophylactically following caesarean section.
A Safety and Efficacy Trial of Multiple Dosing Regimens of ABT-719 for the Prevention of Acute Kidney...
Acute Kidney InjuryThis study will evaluate the safety and efficacy of ABT-719 in preventing acute kidney injury in patients undergoing high risk cardiac surgery.
Cethrin in Acute Cervical Spinal Cord Injury
Spinal Cord InjuryThis is a multicenter, randomized, double-blind, placebo-controlled Phase IIb/III study designed to evaluate the efficacy and safety of Cethrin as a treatment for acute cervical spinal cord injury. During the trial, high and low doses of Cethrin will be compared with placebo.
PCORI-1306-02918 Evaluation of Parent-based Programs to Support Children After Traumatic Injury...
Psychological TraumaDepression1 moreChildren presenting to the University of Iowa Health Care System (UIHC), Blank Children's Hospital (Blank), Children's Hospital of Minneapolis, and Kansas City Mercy Children's Hospital with an injury resulting in admission will be the sample population. A child will be included if they are 10-17 years old with an unintentional injury. Consenting children and their parents will be asked to complete a series of four questionnaires: before hospital discharge, at 1-month post discharge, 3-months and 6-months post discharge. The parent-child dyads will be randomized (1:1) to receive 1) training in Link for Injured Kids or 2) Trauma Education. The survey completed in the hospital will be a paper survey or online via an iPad, and follow-up surveys can be completed on paper or online. Aim #1: Assess the feasibility of Link for Injured Kids through qualitative research with parents and providers of previously injured children from UI Children's Hospital. Aim #2: Through a randomized trial, determine the range of potential psychosocial and behavioral health indicators possibly impacted by Link for Injured Kids. This will identify the types of outcomes which could include post-traumatic stress disorder (PTSD), depression, nonspecific distress, quality of life, absenteeism, school performance, coping skills, communication skills, and access to mental health.
Effects of Foot Strengthening on the Incidence of Injuries in Long Distance Runners
Leg InjuriesThe main objective of this trial is to investigate the effects of a training protocol for the foot and ankle complex on the prevalence of running related injuries on long distance runners.
Compatibility of Different Injury Prevention Exercises in Athletes
Injury PreventionThis investigation is aimed to examine the effects of two different exercise-oriented protocols on the knee torque-angle relationship of the knee flexors. Thirty two young soccer players were be randomly assigned to three groups: hamstring-eccentric (ECC, n=11), unstable-squatting (UNS, n=11) or control (C, n=10). The ECC and UNS groups performed eighteen sessions over 6 weeks of an injury prevention protocol, using only 3 hamstring-eccentric or unstable-squatting exercises. The angle-torque relationship was measured before and after the training intervention. Voluntary isometric torque was recorded at six test angles, with participants prone (35º-100º; 0º on full extension).
The Use of a Silver Containing Dressing (Acticoat) on Wound Complication Rates Post Elective Cesarean...
Surgical Wound InfectionThe purpose of this study is to determine the effect of a silver containing dressing (Acticoat Post-Op) compared to a standard dressing (OpSite PostOp) on post elective cesarean section wound complications in obese women (BMI >35).
Effectiveness of CelluTome Epidermal Harvesting System in Autologous Skin Grafting of Chronic Wound...
Wounds and InjuriesThis is multi-center prospective, longitudinal case series with comparison to historical controls.
Ultrasound vs Palpation for Infant Lumbar Puncture
Spinal; PunctureComplicationsThe purpose of this study is to determine if performing an ultrasound to identify the space to insert the needle before performing a lumbar puncture will improve success of the procedure and patient safety.
The Emergency Department Stopping Elderly Accidents, Deaths and Injuries Program
Accidental FallsFalling Injury1 moreThis study aims to determine if a bedside decision aid used in the ED for mechanical fall prevention can increase patient participation in management options that decrease their fall risk. Additionally, the investigators aim to determine if there are gender differences in patient choices in management options and accomplished goals inspired by the decision tool.