search

Active clinical trials for "Intracranial Aneurysm"

Results 71-80 of 331

Aspirin Treatment for Small Unruptured InTracranial Aneurysms With Ischemic cereBrovascuLar diseasE...

Intracranial AneurysmCerebrovascular Disease

The management of small unruptured intracranial aneurysms (UIA) with ischemic cerebrovascular disease (ICVD) has been a very controversial topic in neurosurgery. Thus, we initiated a multicenter, prospective, randomized controlled trial (PROBE) design to elucidate in UIA patients with ICVD who do not qualify for preventive endovascular or neurosurgical intervention whether aspirin treatment decreases the risk of aneurysm growth and rupture.

Not yet recruiting20 enrollment criteria

Aneurysm Treatment Using Intrasaccular Flow Diversion With the ARTISSE™ Device

Intracranial Aneurysm

The purpose of this study is to assess the safety and effectiveness of the Artisse™ Intrasaccular Device in the treatment of bifurcating saccular intracranial aneurysms.

Not yet recruiting15 enrollment criteria

Transradial Access for Ruptured Intracranial Aneurysms Embolization

Transradial Access

The goal of this clinical trail is to compare the difference between transradial access (TRA) and transfemoral access(TFA) for ruptured intracranial aneurysms embolization. The main question it aims to answer is: whether is TRA not inferior to TFA? In the experimental group, the transradial access (TRA) was used, which was to puncture the radial artery and insert a radial sheath to establish a surgical pathway for embolization of the aneurysm; In the control group, transfemoral access (TFA) was used to embolize the aneurysms, which was to puncture the femoral artery and insert the femoral sheath to establish a surgical pathway for embolizing the aneurysms.The two groups of patients received an oral loading dose of aspirin (300mg) plus clopidogrel (300mg) on the day of surgery, while patients who were unable to take orally were given nasal feeding. During the operation, systemic heparinization was performed with a starting dose of 75U/kg intravenous injection, and the injection was halved every 1h until 1000U. After the operation, protamine neutralizing heparin (1mg protamine neutralizing 100U heparin) was used.

Not yet recruiting12 enrollment criteria

Effect of Different Heparinization Schemes on Prognosis of Intracranial Aneurysm

Intracranial Aneurysm

The goal of this clinical trial is to compare intracranial aneurysm patients. The main question it aims to answer are: Which heparinization regimen is most beneficial to patients during surgery for intracranial aneurysms. Participants will be randomized to different intraoperative heparinization regimens: (i) 50 U/kg intravenous (IV) at 1-h intervals reduced by half to a minimum of 1000 u/h; (ii) 60 U/kg IV at 1-h intervals reduced by half to a minimum of 1000 u/h; (iii) 70 U/kg IV at 1-h intervals reduced by half to a minimum of 1000 u/h. MRI will be performed within 72 h after surgery, and the DWI sequence of MRI will be analyzed. If there is a comparison group: Researchers will compare different intraoperative heparinization protocol groups to see which dose of intraoperative heparin has the best prognosis for use.

Not yet recruiting5 enrollment criteria

Dimethyl Fumarate Treatment for Intracranial Unruptured Aneurysms.

Intracranial AneurysmAneurysm2 more

This study was designed to identify whether there is a measurable reduction in inflammation in walls of intracranial aneurysms with oral dimethyl fumarate.

Not yet recruiting12 enrollment criteria

Aneurysmal Subarachnoid Hemorrhage Trial RandOmizing Heparin

Aneurysmal Subarachnoid HemorrhageNeurobehavioral Manifestations4 more

A Blind-adjudication Multi-center Phase II Randomized Clinical Trial of Continuous Low-dose Intravenous Heparin Therapy in Coiled Low-grade Aneurysmal Subarachnoid Hemorrhage Patients with Significant Hemorrhage Burden. - STUDY IS TEMPORARILY SUSPENDED WITH PLAN TO RESUME SOON. NO SAFETY CONCERNS

Suspended33 enrollment criteria

Post-Market Surveillance Study to Evaluate the Long-Term Safety and Effectiveness of the LVIS Device...

Intracranial Aneurysms

The proposed study is a multi-center single arm retrospective and prospective data collection, of patients treated with the LVIS device of specific sizes of 3.5mm, 4.0mm, 4.5mm, 5.5mm with up to 5 years follow-up. Information collected during the study will be standardized across centers to include pre-treatment baseline characteristics of patients including aneurysm(s) symptoms, procedural information, prespecified clinical safety events of interest, and follow-up imaging, clinical visits or telephone calls.

Enrolling by invitation10 enrollment criteria

Treatment Strategies for Unruptured Intracranial Aneurysms in the Chinese Population China Treatment...

Unruptured Intracranial Aneurysm

The goal of this prospective observational cohort study is to learn about treatment strategies for unruptured intracranial aneurysms in the Chinese population. The main questions it aims to answer are: To establish a cohort of patients with intracranial unruptured aneurysm and explore the optimal clinical treatment strategy. To establish clinical management path for patients with unruptured intracranial aneurysm. According to the treatment of all patients with unruptured intracranial aneurysm, they were divided into the following groups: 1. Conservative treatment group; 2. Intracranial aneurysm clipping group; 3. Coil embolization or stent-assisted coil embolization group; 4. Flow diversion group.

Recruiting10 enrollment criteria

Florida Cerebrovascular Disease Biorepository and Genomics Center

Cerebrovascular DiseaseIschemic Stroke17 more

The purpose of this study is to create a state-wide biorepository and resource center for cerebrovascular diseases in Florida, which will include collecting medical history information and blood from families affected by cerebrovascular disease. The information and blood samples collected may be used in future research for the study of cerebrovascular disease and to learn about, prevent or treat other health problems.

Recruiting10 enrollment criteria

Swiss Study on Subarachnoid Hemorrhage

Subarachnoid HemorrhageIntracranial Aneurysm

This registry was created to assess management parameters of patients treated for aneurysmal subarachnoid hemorrhage in Switzerland. All Swiss hospitals with a neurosurgery department, an intensive care unit and an interventional neuroradiology team that treat neurovascular emergencies participate in the registry. Clinical parameters are entered into a common database. This database will provide (1) a nationwide assessment of the current standard of care and (2) the outcomes for patients in Switzerland including neuropsychological assessments.

Recruiting2 enrollment criteria
1...789...34

Need Help? Contact our team!


We'll reach out to this number within 24 hrs