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Active clinical trials for "Joint Diseases"

Results 541-550 of 701

Evaluation Of Efficacy Of Liquid Platelet Rich Fibrin In Temporomandibular Joint Disorders

Temporomandibular Joint Disorders

This randomized clinical trial aims to evaluate the efficacy of liquid platelet-rich fibrin administration at different Wilkes stages.

Unknown status10 enrollment criteria

A Combined Nerve Block in Elderly Patients Subjected to Total Hip Replacement

Arthropathy of Hip

The purpose of this study is to validate the hypothesis that a combined nerve block produces better outcomes including intraoperative stress, hemorrheological indexes, postoperative immune function, and incidence of postoperative complications than general anesthesia.

Unknown status14 enrollment criteria

Myofascial Therapy in Patients With Hemophilic Arthropathy

Hemophilia

Designing a treatment protocol using myofascial therapy for the treatment of pain and restrictions on mobility in patients with hemophilic arthropathy of the knee and ankle. Pilot with a small number of patients for assessment the effectiveness and safety of the treatment protocol created. Randomized clinical trial to assess the effectiveness of treatment with myofascial therapy in patients with hemophilia. Describe the differences in terms of the dependent variables (range of motion, pain and flexibility) in patients with hemophilia who have carried out the treatment. Report the relationship between the clinical characteristics of patients and the results obtained after the treatment period.

Unknown status9 enrollment criteria

Multi-Site, Post-Market Study of the ICONACY I-Hip System

Degenerative Joint Disease

The purpose of this study is to evaluate the use and efficacy of the I-Hip for primary total hip replacement surgery.

Unknown status25 enrollment criteria

Effect of the Use of an Occlusal Plate on the Postural Alignment

Temporomandibular Joint Disorders

The possible relationship between posture and instability of the masticatory muscles related to occlusion thus becomes the reason, the objective of this study. In this way, it will be possible to evaluate both postural alignment and postural balance in patients with signs and symptoms of temporomandibular joint disorder before and after the use of an occlusal plate. Our research will take place at the School of Odontology of the University of São Paulo in the clinics of the Occlusion and TMJ Services (SOA) and of the Envelhecer Sorrindo program, and the data will be collected in the Biophysics Laboratory of the School of Physical Education and Sports of the University of São Paulo. The population studies will be made up of 120 patients, 60 being part of the sample and the other 60 in the control group. All the patients in this study are over 20 years of age and are of both genders; the research criteria will be diagnosed by way of filling out the questionnaire of the RDC-TMD and complemented by way of diagnostic imaging via MRI of the temporomandibular joint. The study will be a clinical, randomized, controlled, prospective study and intervention. After the subjects' alignment is evaluated by way of photographs and their postural balance by way of a force platform, the group will the randomized; the sample group will receive an occlusal plate with criteria for occlusal stability (simultaneous, bilateral contacts with an absence of interference in the canine and anterior guides). The occlusal plate will be made from "Vacuum Form" acetate with a thickness of 1.5 mm; the simultaneous, bilateral, occlusal contacts and the canine and anterior guides will be obtained by way of autopolymerizable, acrylic resin with the mandible in a centric relationship. The occlusal plate will be controlled weekly. The control group will only receive orientation to do physiotherapeutic exercises seeking to correctly position the mandible in the resting position (maxillar teeth should be approximately 2 mm away from the mandibular teeth) while the tip of the tongue is positioned and accommodated on the roof of the mouth over the incisive papilla on the hard palate (without touching the teeth). The exercise will consist of repeatedly opening the mouth with the tongue cleaving to the roof of the mouth, 3 times per day, each period consisting of 3 sets with 15 repetitions. After 3 months, the two groups will be re-evaluated in terms of postural alignment and balance.

Unknown status14 enrollment criteria

Stimulation of the Proprioceptive Trigeminocardiac Reflex

Temporomandibular Joint Disorders

Study over muscular stretching to reduce pain the oral cavity.

Unknown status2 enrollment criteria

Study of Adalimumab to Lower Cardiovascular Risk in RA Patients With Well Controlled Joint Disease...

Rheumatoid ArthritisCardiovascular Disease

Rheumatoid arthritis patients are at increased risk of cardiovascular disease because of systemic inflammation that can persist even in patients with well-controlled joint disease. We hypothesize that adding an anti-tumor necrosis factor medication, adalimumab, to standard non-biologic therapy for rheumatoid arthritis will improve endothelial function (reduce cardiovascular risk) in these patients. The design of the trial is as follows: 18 month prospective, randomized, double-blind crossover trial comparing the addition of adalimumab to the addition of placebo. The primary endpoint is a change in endothelial cell function, as detected by brachial artery FMD, at 6 months of adalimumab treatment compared to 6 months of placebo.

Completed45 enrollment criteria

Study to Evaluate the Use of Ultrasound in the Diagnosis of Hemophilic Joint Disease

Inherited Bleeding Disorders

The purpose of this study is to see whether power Doppler sonography (PDS) can be used to diagnose synovitis in patients with inherited bleeding disorders.

Completed11 enrollment criteria

Intraosseous Vancomycin in Primary Total Hip Arthroplasty - Designing a Protocol

Prosthetic Joint InfectionVancomycin1 more

The objective of this study is to evaluate a novel vancomycin intraosseous administration protocol vs a standard IV vancomycin administration protocol for primary total hip arthroplasty patients.

Completed10 enrollment criteria

Magnetic Resonance Imaging of Medial Meniscal Posterior Root Tear

Medial MeniscusPosterior Horn Derangement

The aim of this study is to evaluate and analyze the role of magnetic resonance imaging in the diagnosis of medial meniscal posterior root tears, including the normal variations in meniscal anatomy that may resemble a meniscal tear, and identifying the causes or nature of posterior medial meniscal root tear(degenerative versus traumatic) and correlate the results with the standard reference knee Arthroscopy.In addition to identifying and estimating the suspected cases of meniscal extrusion by making MRI with stress varus overloading simulating weight bearing.

Completed2 enrollment criteria
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