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Active clinical trials for "Leg Ulcer"

Results 41-50 of 287

A Clinical Investigation to Follow the Progress of Exuding Chronic Venous Leg Ulcers Using a Non-Bordered...

WoundsWound of Skin2 more

The goal of this clinical trial to follow the progress of wounds in those with chronic venous leg ulcers while using a non-bordered foam dressing. The main objective is to follow the progress of these wounds over time from initial visit to each follow-up visit. Participants will be asked to wear the dressing for up to 6 weeks of treatment or until healed, changed at every one-week interval.

Recruiting12 enrollment criteria

A Research Study to Evaluate the Safety and Potential Efficacy of ON101 Cream for the Treatment...

Venous Leg Ulcers (VLU)

A Research Study to evaluate the safety and potential efficacy of ON101 cream for the treatment of venous leg ulcers.The objectives of the study are to determine the safety and to explore the potential efficacy of ON101 cream in patients with venous leg ulcers.

Recruiting33 enrollment criteria

A Clinical Investigation to Follow the Progress of Exuding Chronic Wounds Using Mepilex® Up as the...

WoundsWound of Skin4 more

The goal of this clinical trial is to follow the progress of wounds in those with venous leg ulcers and diabetic foot ulcers while using an absorbent dressing called Mepilex Up. The main objective is to follow the progress of these wounds over time from initial visit to each follow-up visit. Participants will be asked to wear Mepilex Up dressing for up to 6 weeks of treatment or until healed, changed at every one-week interval.

Recruiting12 enrollment criteria

Developing Strategies for Effective Debridement in Patients for Venous Leg Ulcers

Venous Leg Ulcer

The goal of this project is to use genomic profiling, candidate genes and proteins to develop guided surgical debridement to improve healing in chronic non-healing venous leg ulcers (VLUs) and to test the efficacy of this approach.

Recruiting25 enrollment criteria

Open Label Single Arm Proof of Concept Trial to Evaluate the Efficacy and Safety of Cytori Celution...

Venous Leg UlcerAutologous Adipose Stromal Vascular Fraction2 more

To evaluate the efficacy and safety of Cytori Celution System in Hungarian patients with chronic non-healing venous leg ulcers.

Recruiting29 enrollment criteria

Open Label Single Arm Proof of Concept Trial to Evaluate the Efficacy and Safety of Cytori Celution...

Diabetic Foot UlcerLeg Ulcer3 more

To evaluate the efficacy and safety of Cytori Celution System in Hungarian patients with diabetic leg ulcers.

Recruiting30 enrollment criteria

A Multicentre European Study to Evaluate Granulox® Used in the Treatment Pathway of Predominantly...

Venous Leg Ulcer

The investigation is designed as an open label, randomized, prospective, assessor blinded, multi centre investigation. 254 evaluable subjects will be randomized to either standard of care group or standard of care with Granulox added as an adjunct therapy in predominantly venous leg ulcer subjects. Standard of care wound management will be completed, including wound cleansing, debridement if necessary and application of a suitable dressing and compression system until complete wound closure. The study will be divided into two phases. Firstly, a two week run-in period to ensure compliance to compression therapy followed by a 20 weeks treatment period starting with randomization and allocation of treatment.

Active27 enrollment criteria

Effect of rhGM-CSF on the Healing of Venous Leg Ulcers

Venous Leg Ulcer

The objective of this study is to examine whether local administration of the growth factor rhGM-CSF incorporated into a hydrogel, can accelerate wound healing when applied to venous leg ulcers, and whether this is safe.

Active46 enrollment criteria

Comparing a Synergistic Antimicrobial Cleanser and Gel to Normal Saline and an Amorphous Gel in...

Wound of Skin

The study is a randomized double-blind controlled clinical trial designed to compare healing rates between normal saline wash in combination with an amorphous gel (NSS-HG) versus the grouping of a synergistic antimicrobial cleanser (AMC) and antimicrobial gel (AMG) in chronic lower extremity ulcers. After consenting, the ulcers of eligible subjects are measured, photographed and undergo the MolecuLight imaging procedure (MiX). The subject is then randomized to one of two arms: target ulcer cleansed saline wash and an amorphous gel (NSS-HG) or synergistic antimicrobial cleanser (AMC) and antimicrobial gel (AMG). After cleansing the wound a second MiX is performed. The subject is given a four-week supply.

Active23 enrollment criteria

Comparison of Zero- and Two-centimeter Distance From Sapheno-femoral Junction in Laser Ablation...

Varicose VeinsVenous Reflux2 more

EVLA is used in in treating refluxing veins, commonly the GSV. The tip of catheter is usually placed 2-2.5 cm distal to the sapheno-femoral junction. This technique theoretically provides the lowest risk for endothermal heat-induced thrombosis (EHIT). In the present study we aimed to evaluate the zero-distance technique (the kissing technique) compared to 2-cm distance from SFJ valve in ablating incompetent GSV.

Active2 enrollment criteria
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