Efficacy of Levodopa/Carbidopa/Entacapone vs Levodopa/Carbidopa in Parkinson's Disease Patients...
Parkinson's DiseaseThe study evaluated the efficacy of levodopa/carbidopa/entacapone vs levodopa/carbidopa in patients with Parkinson's disease and early wearing-off with levodopa
A Non-Blinded Study Demonstrating the Effectiveness and Safety of Azilect Alone or in Combination...
Parkinson's DiseasePatients with Parkinson's Disease (PD) will be divided into 2 groups at each study center at their first visit based on the drugs they are taking for their PD: Group 1 Patients using Azilect and no other therapy. Group 2 Azilect in combination with other medications like Levodopa, Mirapex, or Requip.
Study to Evaluate the Safety and Tolerability of Rasagiline in Advanced Parkinson's Disease Patients...
Parkinson's DiseaseThis is a study to look at the effectiveness, tolerability, and safety of one dose of rasagiline in advanced Parkinson's disease (PD) patients who have been treated with Levodopa/Carbidopa therapy.
Study of KW-6002 (Istradefylline) in Parkinson's Disease in Patients With Motor Response Complications...
Parkinson's DiseaseThe purpose of this study is to confirm the long term tolerability and safety of oral 20 or 40 mg/d doses of Istradefylline.
A Study of Istradefylline (KW-6002) for the Treatment of Parkinson's Disease
Parkinson's DiseaseThe purpose of this study is to evaluate the efficacy of 40 mg a day of istradefylline (KW-6002) for reducing the percentage of awake time spent in the OFF state in patients with advanced Parkinson's disease treated with levodopa.
Effects of Carbidopa/Levodopa/Entacapone on Motor Function and Quality of Life in Patients With...
Parkinson's Disease With End of Dose Wearing OffTo assess motor function and quality of life (QoL) in Parkinson's disease (PD) subjects with end-of-dose wearing off, comparing immediate and delayed switch to carbidopa/levodopa and entacapone.
Phase 2 Clinical Study of KW-6500 in Parkinson's Disease Patients With Motor Response Complication...
Parkinson's DiseaseThe purpose of this study is to evaluate the efficacy of KW-6500 versus placebo when administered as a subcutaneous injection at the individualized maintenance dose level in an OFF state in Parkinson's disease patients with motor response complications on levodopa therapy.
A Study of MK0657 in Parkinson's Disease Patients (0657-006)
Parkinson's DiseaseIn this clinical trial, the safety of MK0657 when given with levodopa will be assessed in patients with Parkinson's Disease. This study will also measure the effectiveness of MK0657, when given in combination with levodopa, to improve motor symptoms and ameliorate dyskinesias (uncontrolled movements of a part of the body) as compared to placebo.
Investigational Parkinson's Disease In Patients Not Well Controlled On L-dopa
Parkinson DiseaseThe purpose of this double-blind, placebo controlled study is to evaluate the safety and effectiveness of an investigational Parkinson's disease drug in patients with advanced disease who are not well-controlled on their L-dopa medication.
Study of Efficacy, Safety and Tolerability of Levodopa-Carbidopa Intestinal Gel in Levodopa-Responsive...
Advanced Parkinson's DiseaseThe primary objective of this study was to demonstrate the superiority of levodopa - carbidopa intestinal gel over treatment with optimized oral levodopa/carbidopa during 12 weeks.