Active clinical trials for "Liver Diseases"

Hepatitis C virus (HCV) infection causes different disease spectrum ranging from minimal progressive liver disease to cirrhosis or hepatocellular carcinoma. Evidence indicates that host genetic factor may play a role in determining disease progression. It is known that many cytokine polymorphisms affect disease progressin via increasing hepatic fibrosis that are key factors in progressing liver injury. By combinations of fibrosis-relating gene polymorphisms, this study aims to identify patients with high risk for progressive liver disease. These patients need intensive therapy to decrease morbidity and mortality of chronic HCV-related liver disease.

This research study is a randomized trial to evaluate a training program that is designed to improve the communication skills of clinicians. The training program focuses on care for patients with serious illnesses and their family members, and assesses effectiveness using patient and family outcomes. The long term goal of this research is to improve communication skills of doctors and nurses, thereby improving patient and family outcomes.

This study is designed to assess the effect of hepatic impairment on the pharmacokinetics, safety and tolerability of udenafil in subjects with hepatic impairment compared to healthy subjects.

The purpose of this study is to evaluate and establish whether lorcaserin dose adjustment is required in patients with mild or moderate hepatic impairment.

The primary objective for this study is to assess safety and performance of the Kronos Electrocautery Device for electrocautery procedures following coaxial biopsy procedures on areas that include, but are not limited to, liver, kidney, lungs, breasts, soft tissue, etc.

The primary purpose of this study is to compare the pharmacokinetics (PK) of a single oral dose of mitapivat in participants with moderate hepatic impairment to that in matched healthy control participants with normal hepatic function.

This study will assess the effect of hepatic impairment on the pharmacokinetics (PK), safety and tolerability of ZSP1273.

Due to Prolonged diseased Condition, Patients are not able to care for themselves and even avoid movement their range of motion is limited which may develop frailty among Liver disease Patients. This Study aims at assessing Engagement, Competency and Physical Performance of Physical Frail Chronic Liver disease Patients before and after Nurse led Physical therapy. Besides these Parameters effect of Intervention on Physical frailty will also be assessed.

A single blind randomized controlled trial was conducted to compare the effect of counselling and visual aid on the anxiety levels in patients undergoing endoscopy and to investigate the superiority of visual aid over psychological counselling and preparation for the procedure in an informed patient.

Impact of Teach Back of Discharge Information in term of patient Recall of Information and patient Engagement in self-care among Chronic Liver Disease patients admitted in selected wards of ILBS, New Delhi Primary objectives To evaluate the impact of teach back on patient recall of discharge information among Chronic Liver Disease patients. To evaluate the impact of teach back on engagement in self care among Chronic Liver Disease patients. Secondary objectives To find the association of health literacy with patient recall in experimental group after discharge information. To find the association of health literacy with patient engagement in experimental group after discharge information. To find the association of patient recall with selected demographic and clinical variable in experimental group after discharge information. To find the association of engagement in self-care with selected demographic and clinical variable in experimental group after discharge information. Assumptions The current study is conceptualized on the basis of the following assumptions It is assumed that the patients health information need to be focused on individual needs to improve their health literacy (Yen&Leasure,2019). It is assumed that teach back method will improve patient's immediate and short term recall of discharge information(Mahajan et al,2020). It is assumed that teach back will support self management and promote health outcome(Yen & Leasure, 2019).