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Active clinical trials for "Low Back Pain"

Results 241-250 of 2244

Spinal Manipulation With Laser Therapy Versus Dry Needling in Chronic Lower Backache

Low Back Pain

To determine the effectiveness of spinal manipulation with laser therapy versus dry needling for pain, disability and fear of movement in chronic low backache

Recruiting3 enrollment criteria

Effect Virtual Reality Fully Immersive Based Exercise Game on Reducing Fear of Movement in People...

CLBP - Chronic Low Back Pain

Low back pain is one of the most common problems among adults and a leading cause of disability worldwide including in Saudi Arabia (Buchbinder et al., 2018) (Awaji, 2016) . Studies have shown that 80% of adults would experience low back pain at least once in their lifetime (Awaji, 2016). Research has shown that physical exercises are the most effective rehabilitation method. However, some CLBP patients have fear of movement and fear of increasing the pain (Alamam et al., 2019b), which will lead to inactivity and more disability. Moreover, low adherence to the prescribed exercise program is very common, which could be due to complexity of the program, boredom or lack of supervision and follow up(Elbur, 2015). VR fully-immersive -based exercise game can be used to enhance CLBP rehabilitation by keeping the patients engaged in the virtual environment distracting them from pain and stopping the cycle of fear of movement. Based on the previous problem our research questions are: Will the VR fully immersive based exercise game improve patient outcomes (fear, pain, reduce disability and improves physical function and adherence)? Aims of the Study. To assess the effectiveness of the VR fully immersive-based exercise game in the rehabilitation program for patients with CNSLBP with kinesiophobia, in reducing fear of movement, pain-related to disability, and improving physical function. To assess the adherence of the VR-based exercise, which has entertainment aspect is better than adherence to the conventional paper-based exercise.

Active10 enrollment criteria

A Prospective Study of Clinical Outcomes Following a Single Intradiscal Injection of Bone Marrow...

Degenerative Disc DiseaseSpine Degeneration

This single-institution prospective case series (single arm) study will assess the clinical outcomes of patients diagnosed with 1 or 2 level level discogenic low back pain following an intradiscal injection of bone marrow aspirate concentrate (BMAC).

Active26 enrollment criteria

Biofreeze® vs. a Placebo on Chronic Low Back Pain Walking Gait Characteristics and Pain

Chronic Low Back Pain

The purpose of this study is to determine the effect of Biofreeze® versus a placebo on walking gait characteristics and pain during walking in individuals with cLBP.

Active2 enrollment criteria

Cryoneurolysis Outcome on Pain Experience (COPE) in Patients With Low-back Pain

Chronic Low-back PainFacet Joint Pain3 more

This study will provide information on the effectiveness of cryoneurolysis for patients with facet joint pain syndrome, and help to establish whether cryoneurolysis should be implemented in clinical practice for this patient population.

Active9 enrollment criteria

Cooled RFA vs Conventional RFA to Manage Chronic Facetogenic Low Back Pain

Chronic Low-back Pain

This study is being conducted to assess the relative effectiveness of radiofrequency neurotomy in subjects with chronic axial low back pain originating in the lumbar facet joints using the COOLIEF* Cooled Radiofrequency Probe as compared to the same procedure conducted using a Standard Radiofrequency Probe.

Active37 enrollment criteria

Acupuncture for Chronic Low Back Pain in Older Adults

Chronic Low-back Pain

The main goal of the BackInAction research study is to determine the effectiveness of a standard course of acupuncture (15 sessions of acupuncture over 3 months) and an enhanced course of acupuncture (an additional 6 sessions of acupuncture over months 4-6) in improving back-related disability in older adults (65+ years) with chronic low back pain compared to usual care alone. Key secondary aims are to determine the effectiveness of acupuncture in improving a composite score of pain intensity and pain interference.

Active20 enrollment criteria

Medtronic Closed-Loop Spinal Cord Stimulation System

Low Back PainLeg Pain1 more

The purpose of the study is to further understand the closed-loop feature in chronically implanted patients by characterizing the efficacy of the next generation, spinal cord stimulator.

Active16 enrollment criteria

Combining Non-invasive Brain Stimulation and Exercise to Treat Low Back Pain

Chronic Low-back Pain

The aim of this study is to evaluate the efficacy of repetitive transcranial magnetic stimulation alone and in combination with motor control exercises on pain and disability for patients with chronic non-specific low back pain.

Active10 enrollment criteria

Efficacy of Intradiscal Injection of BM-MSC in Subjects With Chronic Low Back Pain (LBP) Due to...

Recurrent Low Back PainDegenerative Disc Disease (DDD)

This will be a multicenter, prospective, double blind, randomized phase 2/3 trial comparing culture-expanded allogeneic adult BM-MSCs with sham-treated controls. This trial will evaluate the efficacy of intradiscal injection of BM-MSCs in chronic low back pain due to lumbar degenerative disc disease (DDD) unresponsive to conventional therapy . Visual analog scale (VAS) and functional status (by Oswestry Disability Index - ODI) will be evaluated 12 months after treatment, defining responders in case of improvement of VAS for pain of at least 20% and 20 mm between baseline and month 12, or improvement of ODI of 20% between baseline and month 12.

Active23 enrollment criteria
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