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Active clinical trials for "Macular Degeneration"

Results 1271-1280 of 1337

Online Validation of Dietary Intake Food Frequency Questionnaire Over Four Weeks, and Electronic...

Lutein and Zeaxanthin Dietary IntakeAge Related Macular Degeneration2 more

Tools to investigate dietary lutein and zeaxanthin (L/Z) intake and electronic device (ED) use are important to progress research that investigates the role of ED blue light (BL) exposure, and dietary L/Z intake on macular health. This project aims to validate two questionnaires developed by our research group: The L/Z FFQ, and the Electronic Device Use Questionnaire (EDUQ). The L/Z FFQ aims to investigate dietary intake of L/Z over the prior week or month. The EDUQ aims to investigate usual hours and behaviours surrounding ED use over the prior three months. This aims of this project are to: Validate a L/Z FFQ recalling over a weekly and monthly timeframe against multiple 24-hour diet recalls over four weeks. Validate the EDUQ against multiple 24-hour ED use diaries over eight weeks. A cohort of 100 adults will be invited to participate to validate the FFQ and EDUQ. Participants will be offered to choose to participate in one or both the questionnaire validations (L/Z FFQ and EDUQ).

Completed4 enrollment criteria

Observational Study of Vision Improvement in Patients With Retinal Disorders

Age-related Macular DegenerationDiabetic Macular Edema

The purpose of this study is to assess the vision improvement achieved by patients with retinal disorders who received corneal treatments by a low vision aid device.

Completed9 enrollment criteria

Prediction of Progression of Age-Related Macular Degeneration

Macular DegenerationMacular Degeneration3 more

The goal for this study is to initiate a randomized, controlled clinical trial to test the viability of personalized AMD progression prediction models. Early and intermediate AMD patients will be recruited and randomly assigned them to a control or test group. The test group will include patients who will receive personalized follow-up care based on their predicted risk, and collect baseline and follow-up data. This work will advance the AMD field by improving the identification of high-risk patients as candidates for more frequent screening and earlier treatment, leading to better clinical outcomes.

Unknown status6 enrollment criteria

Patient's Feelings After Receiving a Diagnosis of Age-related Macular Degeneration

Age Related Macular Degeneration

Age-related macular degeneration (AMD) is the leading cause of blindness in the elderly population of the industrialized world. AMD is a progressive degenerative disease affecting the central area of the retina, responsible for distinct vision. Vision loss arises from aberrant new vessel growth which causes the accumulation of blood or fluid within the retina's thickness and eventually leads to permanent scarring. The two major forms of AMD are exudative, or neovascular or "wet", and non-exudative, or "dry". Vascular endothelial growth factor (VEGF) represents the key modulator of the angiogenetic process and is involved in the pathophysiology of AMD. Anti VEGF therapies are used to treat wet-AMD. After diagnosis and explanations of the practionner, the patients and their close relatives have still frequently many questions about the intravitreal injections, the prognosis, the risk of visual impairment, etc. Few teams have studied the modalities of diagnosis announcement and the understanding of the patients on the disease course. The aim of this study is to evaluate the feelings after the AMD diagnosis announcement as well as the understanding of the possibilities of treatment and the clinical surveillance.

Completed8 enrollment criteria

Vitrectomy and Scleral Shortening for Macular Hole Retinal Detachment or Myopic Traction Maculopathy...

Macular Hole Retinal DetachmentMyopic Traction Maculopathy

The medical records of 16 eyes of 16 patients with macular hole retinal detachment or myopic traction maculopathy who received viterctomy including internal limiting membrane peeling and scleral shorting surgery were reviewed. Best-corrected visual acuity, axial length, retinal reattachment and macular hole closure, the shape of staphyloma determined by optical coherence tomography and 3-dimensional magnetic resonance imaging were assessed.

Completed2 enrollment criteria

Genetic Load and Phenotype in Aggressive AMD

Age-related Macular Degeneration

Patients with AMD will provide cheek cell samples to determine if their is a correlation between genotype (DNA markers) and phenotype (the type of AMD the patient has).

Completed7 enrollment criteria

Measurement and Analysis of Macular Retinal Pigment Epithelium (RPE) Elevations With Cirrus HD-OCT...

Drusen Stage Macular Degeneration

The objective of this study is to compare the areas designated as elevated retinal pigment epithelium (RPE) by the Cirrus HD-OCT versus those designated as drusen on color fundus photographs (CFPs).

Completed10 enrollment criteria

Epidemiological Study of the Prevalence of Age-Related Macular Degeneration in Portugal

Age-Related Macular Degeneration

This is an epidemiological study to assess the the prevalence of Age-Related Macular (ARM) Degeneration in Portugal.

Completed2 enrollment criteria

Home Vision Monitoring Using the ForeseeHome Device Following Treatment of Neovascular Age Related...

Age Related Macular DegenerationChoroidal Neovascularization

ForeseeHome, an FDA-approved home device, was specifically designed for unsupervised Preferential-Hyperacuity-Perimeter (PHP) testing of Age Related Macular Degeneration (AMD) patients at home by characterizing central and paracentral metamorphopsia . The purpose of the current study is to evaluate if, in post-treatment patients, PHP parameters as measured with the ForeseeHome are in agreement with clinical decisions and retinal characteristics as measured with optical coherence tomography (OCT).

Completed18 enrollment criteria

Age-Related Macular Degeneration (AMD) - Beta Study Telemedicine Assessment

Age-Related Macular Degeneration

The purpose of this study is to evaluate the compliance of the Foresee Home device in intermediate AMD patients.

Completed3 enrollment criteria
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