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Active clinical trials for "Mania"

Results 21-30 of 78

Open Label Extension Study of Licarbazepine in the Treatment of Manic Episodes of Bipolar I Disorder...

Bipolar Disorder

This extension study is designed to assess the long-tem tolerability and safety of licarbazepine in patients who completed the 6-week double-blind study CLIC477D2303.

Completed5 enrollment criteria

Methylphenidate for the Treatment of Acute Mania

Mania

This study aims at evaluating the efficacy and safety of methylphenidate in the initial treatment of acute mania in patients with bipolar affective disorders.

Completed21 enrollment criteria

Effects of Pentazocine Versus Lorazepam on Manic Symptoms

Bipolar DisorderSchizoaffective Disorder3 more

Pilot data indicates that pentazocine decreases manic symptoms in hospitalized individuals. To follow up these initial findings, we plan to conduct a larger, more rigorous, double-blind study. We will examine whether pentazocine, an agent with kappa-opiate activity, decreases manic symptoms.

Completed12 enrollment criteria

Study of Licarbazepine in the Treatment of Manic Episodes of Bipolar Disorder

Bipolar Disorder

This purpose of this study is to evaluate the safety and efficacy of Licarbazepine for the treatment of manic episodes of bipolar disorder.

Completed8 enrollment criteria

Quetiapine for Mania In Preschool Children 4 to 6 Years of Age With Bipolar Disorder

Bipolar DisorderMania

This is an 8-week open-label study aimed at assessing the effectiveness and tolerability of Quetiapine, in the treatment of preschool children aged 4 to 6 years with bipolar and bipolar spectrum disorder. This is an exploratory, pilot study, seeking to determine whether Quetiapine is efficacious and well tolerated in the treatment of preschoolers with pediatric bipolar and bipolar spectrum disorder in this age group. The study results will be used to generate hypotheses for a larger randomized controlled clinical trial with explicit hypotheses and sufficient statistical power.

Completed20 enrollment criteria

Risperidone Versus Olanzapine for Mania in Preschool Children 4 to 6 Years of Age With Bipolar Disorder...

Bipolar DisorderMania

The objectives of this study are to study the safety, effectiveness, tolerability and dosing regimen of risperidone, and olanzapine, in the treatment of mania in Bipolar Disorder I and Bipolar II Disorder in preschool children over an 8 week period. We hypothesize that these atypical neuroleptics may be effective in treating pediatric mania, with a lower risk of extrapyramidal side effects.

Completed18 enrollment criteria

Six Month Trial of Lamotrigine vs. Sodium Valproate for Treatment of Mixed Mania

Mixed Mania Bipolar Disorder

We are comparing the efficacy of Lamotrigine to that of Standard of Care Sodium Valproate for the treatment of Mixed Mania. The study hypothesis is that Lamotrigine will be more efficative for treating mixed mania in patients with Bipolar Disorder.

Completed10 enrollment criteria

A Study of Aerobic Exercise for Adolescents With Subthreshold Mood Syndromes

Depressive SymptomsHypomania Nos Single Episode or Unspecified

This study will investigate the effects of aerobic exercise on mental states, cognition, and long-term outcomes in adolescents with subthreshold depressive and/or hypomanic syndromes and in non-clinical school children

Completed13 enrollment criteria

Safety and Efficacy of Cariprazine for Bipolar I Disorder

ManiaBipolar I Disorder

The objective of this study is to evaluate the efficacy, safety, and tolerability of cariprazine monotherapy versus placebo for the treatment of acute manic or mixed episodes associated with bipolar I disorder.

Completed5 enrollment criteria

Aripiprazole for the Treatment of Mania in Children and Adolescents With Bipolar Disorder

Bipolar DisorderMania

This is an open-labeled study of Aripiprazole, testing its efficacy in the treatment of mania in children and adolescents with Bipolar I, Bipolar II and Bipolar Spectrum Disorder over 8 weeks. This is an exploratory, pilot study, seeking to determine whether Aripiprazole is efficacious and well tolerated in the treatment of youth with pediatric bipolar and bipolar spectrum disorder. The study results will be used to generate hypotheses for a larger randomized controlled clinical trial with explicit hypotheses and sufficient statistical power.

Completed21 enrollment criteria
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