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Active clinical trials for "Persistent Vegetative State"

Results 41-50 of 56

The Use of LIFUP in Chronic Disorders of Consciousness

Disorder of ConsciousnessVegetative State9 more

When patients survive a severe brain injury but fail to fully recover, they often enter a Disorder of Consciousness (DoC) --that is, a set of related conditions of decreased awareness and arousal including the Vegetative State (VS) and the Minimally Conscious State (MCS). When these conditions become chronic, there are no approved treatments to help bolster any further recovery. In prior work, we have shown the clinical feasibility and potential of Low Intensity Focused Ultrasound Pulsation (LIFUP) as a remarkably safe form of non-invasive brain stimulation in these conditions.

Completed13 enrollment criteria

Effectiveness of Sensory Stimulation for Person in a Coma or Persistent Vegetative State After Traumatic...

Brain Injuries

Appraised the empirical evidence of effectiveness of sensory stimulation to improve arousal and alertness for persons in a coma or persistent vegetative state after traumatic brain injury (TBI). Databases were searched and nine articles met inclusion criteria.

Completed2 enrollment criteria

Analysis of Vital, Facial and Muscular Responses Front to Music or Message in Coma, Vegetative State...

Consciousness DisordersCommunication1 more

Objectives: (1) To check music or voice message influence on vital signs, facial expressions or muscular tonus of coma, vegetative or sedated patients; (2) To connect the existence of patient's responsiveness with the Glasgow Coma Scale or with the Ramsay Sedation Scale; (3)To evaluate the relation between the response and the score of Glasgow Outcome Scale.

Completed5 enrollment criteria

The Role of Music Stimulation in Disorders of Consciousness State: an fMRI Study

Vegetative StateMinimally Conscious State

The aim of the present study was to evaluated the neural effect of music on the cerebral activation in unresponsive wakefulness syndrome (UWS) and minimally conscious state (MCS) by using functional magnetic resonance imaging (fMRI).

Completed7 enrollment criteria

Transcranial Direct Current Stimulation Effects in Patients With Chronic Consciousness Disorders...

Minimally Conscious StateTBI

Chronic consciousness disorders have high level of impact on public health and its costs.

Completed5 enrollment criteria

Behavioral Assessment of Nociception on NCS-R

Disorder of ConsciousnessUnresponsive Wakefulness Syndrome1 more

The aim of this study was to investigate the relationship between behaviorally assessed consciousness levels and responsiveness to nociception in patients with disorders of consciousness (DOC)

Completed7 enrollment criteria

Neural, Behavioural, and Clinical Effects of tDCS in PDOC; Feasibility Study

Consciousness DisorderBrain Injuries2 more

This study evaluates the feasibility of an experimental protocol that combines advanced multi-modal imaging of the brain with clinical and behavioural scales to characterise the neural, behavioural, and clinical effects of transcranial direct current stimulation (tDCS) for rehabilitation in PDOC

Unknown status8 enrollment criteria

Target Behaviours to Identify Minimally Conscious State Patients

Disorder of ConsciousnessMinimally Conscious State

To analyse the frequency of the consciousness behaviour response for patients with minimally conscious state of Coma Recovery Scale-Revised items, as well as the necessary items for obtaining higher accuracy. In addition, providing target behaviours for Coma Recovery Scale-Revised assessment of minimally conscious state diagnosis and evidence for the simplification of Coma Recovery Scale-Revised in the future.

Completed2 enrollment criteria

Eye Tracking Technology in the Diagnosis of Neurological Patients

Postcomatose Unawareness StateMinimally Conscious State8 more

Demonstrating that diagnostics of the state of consciousness and cognitive functions of patients with consciousness disorders performed using C-Eye X (based on eye-tracking technology) allows a more objective assessment of state of patients who were wrongly diagnosed based on popular methods using in a clinical practice (like behavioural scales on paper forms).

Completed11 enrollment criteria

The Initiation of Swallowing Can Indicate the Prognosis of DOC

Minimally Conscious StateVegetative State

This study is aimed to detect the initiation of swallowing act in DOC patients, to find if it is a good item as a stimulus and to detect the relationship between the initiation of swallowing act and the prognosis of DOC patients.

Completed9 enrollment criteria
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