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Active clinical trials for "Cardiomyopathies"

Results 1091-1100 of 1105

A Study of Impact of Anemia on Morbidity and Mortality in Children With Dilated Cardiomyopathy

Pediatric Dilated Cardiomyopathy

Dilated cardiomyopathy is a heart muscle disorder characterized by systolic dysfunction and dilation of the left or both ventricles.Dilated cardiomyopathy can develop in people of any age or ethnicity, although it is more common in male than female persons occurring at a ratio of about three to one in male to female persons. Dilated cardiomyopathy is the predominant cause of cardiomyopathy in pediatric populations. Annual incidence in pediatric populations has been reported to be much lower than one to one hundred seventy thousand in the United States and one to one hundred forty thousand in Australia. Although pediatric dilated cardiomyopathy has a lower annual incidence than adult dilated cardiomyopathy, the outcome for pediatric dilated cardiomyopathy patients is particularly severe. Dilated cardiomyopathy is the most frequent cause of heart transplantation in pediatric patients. Data from international pediatric dilated cardiomyopathy registries indicate that the rates of death or heart transplantation over one and five year periods were thirty one percent and forty six percent, respectively. Onset of dilated cardiomyopathy is usually insidious but may be acute in as many at twenty five percent of patients. Approximately fifty percent of patients with dilated cardiomyopathy have a history of preceding viral illness.

Unknown status4 enrollment criteria

Molecular Genetic Screening and Identification of Congenital Arrhythmogenic Diseases

Long QT SyndromeHypertrophic Cardiomyopathy1 more

The aim of this study is the identification of familial congenital arrhythmogenic disorders and their clinical follow-up.

Unknown status7 enrollment criteria

Comparison of Data Obtained by Echocardiography and Magnetic Resonance Imaging in Hypertrophic Cardiomyopathy...

Hypertrophic Cardiomyopathy

Compare data (structural and functional) obtained by transthoracic rest echocardiography and magnetic resonance imaging (with gadolinium) in 30 patients with hypertrophic cardiomyopathy

Unknown status7 enrollment criteria

Risk Stratification in Children and Adolescents With Primary Cardiomyopathy

Primary CardiomyopathyDilated Cardiomyopathy4 more

RIKADA is a prospective study performing systematic family screening including clinical and genetic testing in pediatric patients with primary cardiomyopathy and their first-degree relatives with the aim to facilitate risk stratification.

Unknown status16 enrollment criteria

Assessment of Myocardial Injury in Simultaneous Pancreas and Kidney Transplantation

Simultaneous Pancreas-kidney TransplantationDiabetic Cardiomyopathy

Diabetic cardiomyopathy( DCM) is a major complication of diabetes and is a common cardiovascular complication independent of coronary artery disease and hypertension.Trial to assess of myocardial injury in recipients of simultaneous pancreas and kidney transplantation by nuclear magnetic T2 mapping technology.

Unknown status2 enrollment criteria

A Registry of Peripartum Cardiomyopathy in Turkey

Peripartum Cardiomyopathy

Peripartum cardiomyopathy (PPCM) is a global disease with significant morbidity and mortality of young women. Its' etiology, epidemiology and treatment is not yet well described. This will be a retrospective, national, multicenter observational study, conducted in Turkey. It is expected that approximately 50 women with PPCM will be recorded.

Unknown status4 enrollment criteria

Unmasking the Prevalence of AC in an Unselected Echocardiographic Population

Amyloid Cardiomyopathy

This study will investigate the prevalence of echocardiographic red-flags of amyloid cardiomyopathy (AC) in patients undergoing clinically-indicated echocardiography (observational phase) and the prevalence of AC among AC-suggestive echocardiograms (interventional phase).

Unknown status16 enrollment criteria

Role of Endothelial Function, Muscular Fitness and Metabolism in Functional Activity in Patients...

Chronic Heart FailureCoronary Disease1 more

Shortness of breath, fatigue, and exercise intolerance are clinical symptoms of chronic heart failure (CHF). Recent studies suggested that peripheral impairment was the major cause of clinical symptoms, and mechanism may be related to neuroendocrine impairment and vascular smooth muscle dysfunction. It results in increased peripheral resistance that may influence limb blood flow, muscle fitness and activities of daily.The purposes of this study are to compare muscular strength, endurance, and perfusion of quadriceps between CHF patients and healthy controls by isokinetic test and near-infrared spectroscopy (NIRS) and difference in activities of daily living to compare endothelium function between CHF patients and healthy control subjects the relationship between endothelium function, muscular strength, endurance, perfusion, and metabolism of quadriceps.

Unknown status5 enrollment criteria

Implementation of Work in Progress (WIP) Sequences in Magnetic Resonance Imaging (MRI)

Ischemic CardiomyopathyNonischemic Cardiomyopathy

Trial of new work in progress (WIP) sequences in MRI.

Unknown status3 enrollment criteria

The Cardiovascular Genetic and Therapeutic Implications of Muscular Dystrophy

Muscular DystrophyDilated Cardiomyopathy1 more

This study will have significant impact on muscular dystrophy patients as it promotes early screening for heart disease. With early identification, beneficial medical therapy can be started sooner, resulting in restoring and maintaining normal heart function. This is critical to the survival of these patients. We have reported previously that heart failure in all patients may have common mechanisms, the "final common pathway". Heart failure is a significant health problem with 5 million people in the US carrying the diagnosis and accounting for 12-15 million office visits and 6.5 million hospital days per year. The number of deaths from heart failure continues to increase. The data from this study could impact patients worldwide with heart failure by offering new insight into an ever-growing disease population and lead to significant changes in how they are currently treated.

Unknown status2 enrollment criteria
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