Protein S and Myocardial Infarction
Cardiovascular DiseasesHeart Diseases1 moreTo test the hypothesis that low levels of free protein S, a natural anticoagulant protein in plasma, were associated with an increased incidence of myocardial infarction in middle aged men and women.
Mediators of Social Support in Coronary Disease
Cardiovascular DiseasesCoronary Disease3 moreTo determine prospectively the extent to which structural and functional aspects of social support influences 'hard' cardiac events such as death and non-fatal myocardial infarction in patients with coronary artery disease (CAD) and to identify the behavioral and biological mediators of these influences.
Effect of Drug Therapy on Reinfarction Risk in Women
Cardiovascular DiseasesMyocardial Infarction1 moreTo evaluate the safety of calcium-channel blockers in the secondary prevention of myocardial infarction in women.
Compliance in the Physicians' Health Study
Cardiovascular DiseasesHeart Diseases2 moreTo evaluate the relationships of compliance in taking aspirin or aspirin placebo with the risk of major cardiovascular endpoints, using data collected in the Physicians' Health Study.
Predictors of Cardiovascular Disease in the Elderly
Cardiovascular DiseasesHeart Diseases4 moreTo evaluate factors associated with cardiovascular morbidity and mortality in a cohort of 795 men and women aged 75 years or older at the time of a comprehensive examination conducted between 1984 and 1987.
Homocyst(e)Ine, Vitamin Status, and CVD Risk
Cardiovascular DiseasesCerebrovascular Accident4 moreTo test the hypotheses that the risk of myocardial infarction and/or stroke is associated with elevated plasma levels of homocysteine, and low plasma levels of folate, vitamins B12 and B6.
Observational Aspirin Use and CVD in the Physicians' Health Study
Cardiovascular DiseasesCoronary Disease3 moreTo analyze existing data from the Physicians Health Study (PHS), a randomized primary prevention trial of low-dose aspirin and beta carotene conducted among 22,071 U.S. male physicians, to address questions concerning aspirin and cardiovascular (CV) disease that could not adequately be addressed during the randomized aspirin period.
Using Higher Cut-off Values to Diagnose Acute Myocardial Infarction in Patients With Elevated Hs-cTnT...
Acute Myocardial InfarctionHigh-sensitive cardiac troponin T (hs-cTnT) is a cornerstone for diagnosing acute myocardial infarction (AMI). However, it is often challenging to diagnose AMI in patients with elevated hs-cTnT before a rise or fall of hs-cTnT can be observed. The elevations of hs-cTnT are caused not only by AMI, but also by other cardiac or even non-cardiac diseases. Thresholds above the 99th percentile have been proposed to improve the specificity and to accelerate the rule in of myocardial infarction. This study aimed to find a more accurate cut-off value to rule in AMI in patients with elevated hs-cTnT.
Prediction of Primary Cardiovascular Events Using the Multimarker Approach
Cardiovascular DiseasesStroke3 moreThe study of biochemical risk factors for cardiovascular diseases is important not only for analysis, but also for preventive measures, given that changes in the level of biomarkers can be detected before the first clinical manifestations of CVD. Accordingly, patients at high CV risk may have additional motivation to lead a healthy lifestyle. In addition, information on biochemical risk markers can be used to optimize the clinical management of patients.
In-hospital Versus After-discharge Complete Revascularization
STEMI - ST Elevation Myocardial InfarctionMultivessel Coronary Artery DiseasePatients with STEMI and multivessel disease in whom the culprit lesion has been successfully revascularized during prmimary PCI, will be randomized to in-hospital or after-discharge complete revascularization. The purpose of this study is to evaluate the impact of these two different strategies in terms of hospital stay.