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Active clinical trials for "Myopia"

Results 681-690 of 694

Advanced Surface Ablation (ASA) vs Laser-Assisted In Situ Keratomileusis (LASIK)

NearsightednessFarsightedness1 more

The purpose of this combined retrospective and prospective chart review analysis is to investigate the safety, efficacy, and predictability obtained via Laser-Assisted In Situ Keratomileusis (LASIK) and Advanced Surface Ablation (ASA) over a wide range of refractive errors The working hypothesis is that there will be no difference in clinical outcomes between patients treated with LASIK or ASA.

Unknown status2 enrollment criteria

Study on the Effect of Mitomycin C 0.02% on the Corneal Endothelial After Photorefractive Keratectomy...

Myopia

In this study 126 eyes in 63 patients with moderate bilateral myopia and astigmatism between -3 and -5 (SE difference between two eyes should not be more than 0.75 and the residual corneal thickness>350 μ ) were entered in the study. One eye went randomly under PRK with mitomycin C 0.02% in 15 min and then the other eye went under the operation without MMC. UCVA,BCVA, refractory error after the operation and the number of endothelial cells before and after the surgery would be compared in 6 months.

Unknown status11 enrollment criteria

Real Life Study in Myopic Neovascularization

Myopic Choroidal Neovascularisation

This is a multi centre, single arm, prospective observational phase 4 study in naive or pretreated patients with myopic neovascularization. The patients will be treated with intravitreal injections of Aflibercept following a real life protocol. This sudy aims to evaluate the visual acuity during a 36 months period of time.

Unknown status10 enrollment criteria

The Collaborative Longitudinal Evaluation of Ethnicity and Refractive Error (CLEERE) Study

Myopia

To compare and contrast normal eye growth, ocular component development, and refractive error development in Hispanic, African-American, and Asian schoolchildren with what happens in Caucasian children from the Orinda Longitudinal Study of Myopia. To investigate risk factors for the development of myopia. To conduct DNA-based studies on nearsighted children and their families.

Unknown status1 enrollment criteria

Macular Hemorrhage in Myopic Eyes

Macula Lutea HemorrhageHigh Myopia

Visual impairment in high myopic eyes is mainly due to the different types of myopic maculopathies, such as diffuse or patchy atrophy, lacquer cracks and choroidal neovascularization. Macular hemorrhage was one of those complications. Despite choroidal neovascularization, simple hemorrhage from rupture of Bruch's membrane and choroidal microcirculation is also the cause of hemorrhage. The prognosis of those eyes with simple hemorrhage is generally good. However, some patients had persistently poor vision after the absorption of the hemorrhage. In the literature, the visual prognosis in those patients was reported to be associated with the microstructure change under the optical coherent tomography (OCT) or the presentation of the autofluorescence. The investigators will collect the patients with high myopia and presenting with macular hemorrhage. High resolution OCT and autofluorescence imaging will be used to analyze the change of the microstructure of retina and its correlation with the visual prognosis.

Unknown status5 enrollment criteria

Does Pupil Size Matters in Refractive Surgery?

Myopia

To determine the influence of pupil size in refractive surgery. If any influence exist.

Unknown status2 enrollment criteria

Development and Pathological Changes of High Myopia Among Children and Adolescents in China

High Myopia

The study aims to observe the relationship between the changes of ocular structure parameters and pathological changes among children and adolescents with high myopia. Environmental factors and family history will also be collected to explore their impacts on high myopia progression.

Unknown status8 enrollment criteria

Evaluation of Visual Acuity in Myopic Cataract Patients Using Trifocal Intraocular Lens

CataractMyopia1 more

The PanOptix trifocal IOL is a new trifocal intraocular lens which is proved to provide good range of vision for distance, intermediate and near and good visual quality in cataract patients with normal axial length. But whether it can get the same visual quality in myopia is still unknown

Unknown status10 enrollment criteria

Genomewide Screening of Pathological Myopia

Pathological Myopia

The purpose of this study is to evaluate the possible candidate gene of pathological myopia

Unknown status2 enrollment criteria

Zhaoqing Myopia Study

Myopia

Myopia is a common cause of vision loss, being particularly prevalent in children in East and Southeast Asia. The investigators will assess prevalence and incidence of myopia, identify digital biomarkers associated with myopia, and validate algorithms for the detection and/or predition of myopia and other ocular abnormalities in school-aged children in both urban and rural settings in Southern China.

Unknown status2 enrollment criteria
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