Bioavailability of Vagantin® Coated Tablets Relative to an Oral Methantheline Bromide Solution
Neurogenic BladderThe primary objective of the study is: •To describe extent and rate of absorption of methantheline after single oral dose administration of Vagantin® coated tablets (Test) in comparison to a methantheline bromide solution (Reference) The secondary objectives of the study are: To determine elimination the half-life of methantheline bromide To describe the effects of Test and Reference on salivation, accommodation, pupil response, blood pressure and heart rate to assess frequency and intensity of adverse drug reactions
Connected Catheter Clinical Feasibility Study( CFS)
Urinary BladderNeurogenicThe objective of this study is to evaluate the safety and essential performance of the Connected Catheter System in males with neurogenic lower urinary tract dysfunction (NLUTD), both in an acute clinical setting, and during and extended period (up to 29 days) of home use.
Bilateral vs. Unilateral Stimulation in Neurological Bladder Disroders
Neurogenic Urinary BladderSpasticThis study evaluates the effectiveness of bilateral stimulation of the tibial nerve compared to unilateral stimulation in neurological bladder disorders.
Effect of Tamsulosin vs Prazosin in Treatment of Female Voiding Dysfunction
Neurogenic BladderThe purpose of this study is to determine whether Tamsolusin or Prazosin are effective in the treatment of female voiding dysfunction(BOO)
Mirabegron and Oxybutynin Safety and Efficacy Trial in Spinal Cord Injury
Spinal Cord InjuriesUrinary Bladder1 moreThe purpose of this research study is to determine the effectiveness and safety of mirabegron compared to oxybutynin chloride immediate release (oxybutynin IR) for a condition called neurogenic detrusor overactivity in individuals with chronic spinal cord injury (SCI).
Treatment of Neurogenic Incontinence by Surgery to Cut the Filum Terminale
Neurogenic IncontinenceDysfunctional VoidingThe target population of this study is children with primary or secondary daytime urinary incontinence, who have failed to improve adequately despite compliance with at least 6 months of standard medical therapy. The study hypothesis is that patients who under go cutting the filum terminale - the string-like lower end of the spinal cord - will have improved bladder function at 6-month follow up. Bladder function and its effects on quality of life will be measured before surgery and at 6-month follow up.
Antiseptic-coated Intermittent Urinary Catheter
Neurogenic BladderCatheter-Related InfectionsStudy design is a prospective, randomised, double-blind, and interventional. Primary aim of the study is to investigate efficacy of antiseptic-coated intermittent hydrophilic urinary catheters in prevention and reduction of catheter-associated urinary tract infections in children with neurogenic bladder. Secondary aim is to assess feasibility of antiseptic-coated intermittent hydrophilic urinary catheters in neurogenic bladder management. Octenidine chloride will be used as antiseptic.
Can Dynamic Ultrasonography Replace Urodynamics in Follow-up of Patients With Myelomeningocele
Neurogenic BladderMyelomeningocelePatients with neurogenic bladder need periodic evaluation with urodynamic study, a invasive and uncomfortable procedure. Aim: To evaluate the accuracy of dynamic ultrasonography as a feasible and noninvasive alternative diagnostic method to identify detrusor overactivity in patients with neurogenic bladder
Incidence of Urinary Tract Infection After Urodynamic Investigation
Neurogenic BladderThe purpose of this study is to evaluate the incidence of urinary tract infection after urodynamic investigation and to identify the involved germs.
Reduction of Bladder Injection Pain With Belladonna Opiate Suppository
Overactive BladderUrinary Urge Incontinence3 moreThe purpose of this study is to test whether using belladonna & opiate suppositories (B&Os) can improve patient discomfort during Onabotulinumtoxin A (BoNT) injection into the bladder for treatment of overactive bladder, neurogenic detrusor overactivity, or interstitial cystitis.