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Active clinical trials for "Nociceptive Pain"

Results 51-60 of 74

Guiding Sufentanil Administration With Skin Conductance in Mechanically Ventilated Intensive Care...

Nociceptive Pain

Opioid administration in mechanically ventilated patients in the intensive care unit (ICU) is essential to maintaining patient respiratory and hemodynamic stability. Mechanical ventilation is a persistently nociceptive event that can continuously causes discomfort in the trachealy intubated patient. This can lead to patient-ventilator dyssynchrony, tachycardia, hypertension, and their associated complications. Opioids blunt respiratory drive, which facilitates mechanical ventilation, and decrease the sympathetic response to nociception. However, excessive opiate administration is associated with many adverse events, including respiratory depression, delirium, ileus, nausea, and vomiting. Currently, the standard administration in our institution of sufentanil, a potent opiate, consists of continuous infusions of 0.15µg/kg/h to 0.3µg/kg/h. Mechanically ventilated patients are unable to speak and are often sedated. This greatly impacts the patient's capacity to communicate pain. The use of a nociceptive monitor may be a possible solution. Skin conductance monitoring (Pain Monitor, Med-Storm, Norway), measures the peaks per second of electrical conduction. This non hemodynamic monitor uses skin conduction as a surrogate to nociception (i.e., the patient's unconscious response to a noxious stimulus). It may consequently guide opioid administration in ICU patients towards and avoid the consequences of excessive or inadequate antinociception.

Unknown status4 enrollment criteria

Monitoring Analgesia by ANI (Analgesia The Nociception Index)

Nociceptive PainSurgical Procedure1 more

The objective of this research is to study the variations of the ANI(Analgesia The Nociception Index) according to 2 periods: the "NoStim" period before surgical incision under general anesthesia and the period of hemodynamic reactivity "ReactHemo" peroperative. This period is defined by a 20% increase in FC and / or PAS (the only gold standard today).

Completed11 enrollment criteria

Preanesthetic Analgesia/Nociception Index (ANI) and Propofol Injection Pain

PainAcute2 more

Recently, Analgesia Nociception Index (ANI) has been evaluated for objectively measuring peri-operative pain and to guide intra-operative opioid administration during various surgeries. Propofol injection pain (PIP) is a common problem and can be very distressing to the patient.

Completed3 enrollment criteria

Pain Assessment by Pupil Dilation Reflex (PDR) and Pupillary Pain Index (PPI) in Response to Noxious...

Nociceptive PainMonitoring1 more

After conduction a pilot study, pupillary dilation reflex (PDR) is measured in response to nociceptive stimulation perioperatively.

Completed9 enrollment criteria

Radicle Relief 1: A Study of Health and Wellness Products on Pain and Other Health Outcomes

PainNociceptive Pain1 more

A randomized, blinded, placebo-controlled study assessing the impact of health and wellness products on pain and other health outcomes

Completed13 enrollment criteria

The Correlation Between Sevoflurane and qNOX

Analgesic Adverse ReactionNociceptive Pain1 more

This study purpose to observation the sevoflurane analgesia effect, and using nociception real-time monitoring NOX to test the correlation between the sevoflurane and NOX index.

Completed9 enrollment criteria

Comparation Analgesia Efficiency With Propofol Combine Sevoflurane vs Propofol

Nociceptive PainAnalgesic Adverse Reaction1 more

This study purpose to compare analgesia efficiency of propofol combine with sevoflurane with propofol only using index of Nociception (NOX)

Completed23 enrollment criteria

NoL, HR and MABP Responses to Tracheal Intubation Performed With MAC Blade Versus Glidescope

IntubationNociceptive Pain2 more

Prospective, randomized and controlled who will be conducted in Maisonneuve-Rosemont hospital and whose objectives are: To observe if the alterations of the NoL index and the standard monitoring (Mean Arterial Blood Pressure and Heart Rate) (using the variability of NoL index and standard monitoring, peak NoL index and peak standard monitoring values, and number of time passed over their respective threshold for nociceptive response) are more accentuated after laryngoscopy using the classical MAC blade versus single-use disposable blade of the Glidescope. To observe the nociceptive response (using the variability of NoL index and standard monitoring, peak NoL index and peak standard monitoring values, and number of time passed over their respective threshold for nociceptive response) related to the insertion of endotracheal tube between vocal cords during the intubation. Study plans to enroll 50 adult patients scheduled to undergo either general, gynecological, neurological, orthopedic, plastic or urological surgery under general anesthesia and who necessitate endotracheal intubation.

Completed24 enrollment criteria

C2-C4 Compartment Block Versus Block of Costagliola, in TEAC

Somatic PainNeuropathic Pain

C2-C4 compartment block compared to the Costaiola block, in the control of persistent postoperative pain (somatic and neuropathic) in patients undergoing carotid thromboendarterectomy

Completed10 enrollment criteria

Profile of Pain and Unpleasant Sensations in Patients With Referred Pain

Referred PainSomatic Pain1 more

This feasibility study primarily aimed to assess the technology acceptance and usability of a pain tracking software in patients with spinally referred chronic pain. The secondary aim was to assess the fluctuations in pain intensity and distribution, using the pain tracking software during a 3-month period. Additionally, the study aimed to explore the patients' behavior when self-reporting pain when given the opportunity to use a variety of pain quality descriptors, such as tingling, burning and stabbing. Patients with spinally referred chronic pain will be recruited to participate. Participants will be asked to use a pain tracking software to create weekly pain reports for a 3-month period. These pain reports consist of pain drawings and intensity scales. Additionally, patients will complete baseline disability and pain catastrophizing online questionnaires. The project does not affect treatment or does not offer any intervention.

Completed5 enrollment criteria
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