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Active clinical trials for "Ocular Hypertension"

Results 111-120 of 587

Safety/Efficacy Study: OPA-6566 Ophthalmic Solution in Subjects With Primary Open-Angle Glaucoma...

Primary Open-angle GlaucomaOcular Hypertension

This is a study of the safety, tolerability, pharmacokinetics (measurement of drug levels in the blood), and intraocular pressure lowering effects of OPA-6566 ophthalmic solution in subjects with primary open-angle glaucoma or ocular hypertension.

Completed4 enrollment criteria

Latanoprost Versus Tafluprost: 24-hour Intraocular Pressure (IOP)

Primary Open Angle GlaucomaOcular Hypertension

Main objective is to compare the ability of Latanoprost 0.005% preservative-added ophthalmic solution versus Tafluprost 0.0015% preservative-free ophthalmic solution, both given once a day at the evening, in reducing 24-hour intraocular pressure (IOP) in patients with primary open angle glaucoma (POAG) and/or ocular hypertension (OHT) at first diagnosis. First efficacy variable will be the difference between mean nocturnal IOP values after three months of treatment: nocturnal IOP is defined as the mean value between 2AM and 6AM measurements. Secondary objectives will be the comparison between Latanoprost 0.005% and Tafluprost 0.0015% ophthalmic solution about: Mean 24-hour IOP values after three months of treatment IOP values at these time-points: 10AM (± 1 hour), 2PM (± 1 hour), 6PM (± 1 hour), 10PM (± 1 hour), 2AM (± 1 hour) and 6AM (± 1 hour) after three months of treatment

Completed10 enrollment criteria

Additive Intra-ocular Pressure Reduction Effect of Fixed Combination of Maleate Timolol 0.5%/Dorzolamide...

Glaucoma

The purpose of this study is to evaluate the additive effect of dorzolamide/timolol fixed combination in patients undergoing monotherapy with latanoprost.

Completed2 enrollment criteria

DuoTrav® Eye Drops As Replacement Therapy Program

Open-angle GlaucomaOcular Hypertension

To evaluate the effectiveness of DuoTrav Eye Drops in gaining or maintaining control of target Intraocular Pressures (tIOP) in patients diagnosed with, and being treated for, open-angle glaucoma (OAG) or ocular hypertension (OH).

Completed2 enrollment criteria

Patient Satisfaction With Timolol in Subjects With Open-Angle Glaucoma or Ocular Hypertension

GlaucomaOpen Angle1 more

This study compares patient symptoms and anterior segment safety in patients treated with timolol hemihydrate, generic timolol gel forming solution or timolol maleate.

Completed23 enrollment criteria

Examination of Ocular Surface Effects With Administration of Travatan Z and XALATAN

Open-angle GlaucomaOcular Hypertension

The purpose of this study is to compare two ophthalmic solutions in patients with open-angle glaucoma or ocular hypertension.

Completed16 enrollment criteria

A Study of Open Angle Glaucoma or Ocular Hypertension in Patients Within Scandinavia

Open Angle GlaucomaOcular Hypertension

PhXA41 is not inferior to timolol in reducing intra-ocular pressure

Completed16 enrollment criteria

Safety and Efficacy of Bimatoprost Compared With Latanoprost in Patients With Glaucoma or Ocular...

Ocular HypertensionGlaucoma

The study will compare the safety and efficacy of Bimatoprost and Latanoprost in patients with glaucoma or ocular hypertension

Completed4 enrollment criteria

Evaluation of Hyperemia With the Use of Ocular Prostaglandin Analogues

Open Angle GlaucomaOcular Hypertension

This study will evaluate hyperemia and ocular surface tolerability in patients on prostaglandin analogues

Completed5 enrollment criteria

Adjunctive Study of AL-37807 Ophthalmic Suspension

Open-Angle GlaucomaOcular Hypertension

The purpose of the study is to compare the safety and intraocular pressure-lowering efficacy of AL-37807 ophthalmic suspension vs. Timolol gel forming solution vs. AL-37807 vehicle, all dosed concomitantly with Xalatan, in patients with open-angle glaucoma or ocular hypertension.

Completed7 enrollment criteria
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