Safety/Efficacy Study: OPA-6566 Ophthalmic Solution in Subjects With Primary Open-Angle Glaucoma...
Primary Open-angle GlaucomaOcular HypertensionThis is a study of the safety, tolerability, pharmacokinetics (measurement of drug levels in the blood), and intraocular pressure lowering effects of OPA-6566 ophthalmic solution in subjects with primary open-angle glaucoma or ocular hypertension.
Latanoprost Versus Tafluprost: 24-hour Intraocular Pressure (IOP)
Primary Open Angle GlaucomaOcular HypertensionMain objective is to compare the ability of Latanoprost 0.005% preservative-added ophthalmic solution versus Tafluprost 0.0015% preservative-free ophthalmic solution, both given once a day at the evening, in reducing 24-hour intraocular pressure (IOP) in patients with primary open angle glaucoma (POAG) and/or ocular hypertension (OHT) at first diagnosis. First efficacy variable will be the difference between mean nocturnal IOP values after three months of treatment: nocturnal IOP is defined as the mean value between 2AM and 6AM measurements. Secondary objectives will be the comparison between Latanoprost 0.005% and Tafluprost 0.0015% ophthalmic solution about: Mean 24-hour IOP values after three months of treatment IOP values at these time-points: 10AM (± 1 hour), 2PM (± 1 hour), 6PM (± 1 hour), 10PM (± 1 hour), 2AM (± 1 hour) and 6AM (± 1 hour) after three months of treatment
Additive Intra-ocular Pressure Reduction Effect of Fixed Combination of Maleate Timolol 0.5%/Dorzolamide...
GlaucomaThe purpose of this study is to evaluate the additive effect of dorzolamide/timolol fixed combination in patients undergoing monotherapy with latanoprost.
DuoTrav® Eye Drops As Replacement Therapy Program
Open-angle GlaucomaOcular HypertensionTo evaluate the effectiveness of DuoTrav Eye Drops in gaining or maintaining control of target Intraocular Pressures (tIOP) in patients diagnosed with, and being treated for, open-angle glaucoma (OAG) or ocular hypertension (OH).
Patient Satisfaction With Timolol in Subjects With Open-Angle Glaucoma or Ocular Hypertension
GlaucomaOpen Angle1 moreThis study compares patient symptoms and anterior segment safety in patients treated with timolol hemihydrate, generic timolol gel forming solution or timolol maleate.
Examination of Ocular Surface Effects With Administration of Travatan Z and XALATAN
Open-angle GlaucomaOcular HypertensionThe purpose of this study is to compare two ophthalmic solutions in patients with open-angle glaucoma or ocular hypertension.
A Study of Open Angle Glaucoma or Ocular Hypertension in Patients Within Scandinavia
Open Angle GlaucomaOcular HypertensionPhXA41 is not inferior to timolol in reducing intra-ocular pressure
Safety and Efficacy of Bimatoprost Compared With Latanoprost in Patients With Glaucoma or Ocular...
Ocular HypertensionGlaucomaThe study will compare the safety and efficacy of Bimatoprost and Latanoprost in patients with glaucoma or ocular hypertension
Evaluation of Hyperemia With the Use of Ocular Prostaglandin Analogues
Open Angle GlaucomaOcular HypertensionThis study will evaluate hyperemia and ocular surface tolerability in patients on prostaglandin analogues
Adjunctive Study of AL-37807 Ophthalmic Suspension
Open-Angle GlaucomaOcular HypertensionThe purpose of the study is to compare the safety and intraocular pressure-lowering efficacy of AL-37807 ophthalmic suspension vs. Timolol gel forming solution vs. AL-37807 vehicle, all dosed concomitantly with Xalatan, in patients with open-angle glaucoma or ocular hypertension.