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Active clinical trials for "Ocular Hypertension"

Results 121-130 of 587

Evaluation of Hyperemia With the Use of Ocular Prostaglandin Analogues

Open Angle GlaucomaOcular Hypertension

This study will evaluate hyperemia and ocular surface tolerability in patients on prostaglandin analogues

Completed5 enrollment criteria

Adjunctive Study of AL-37807 Ophthalmic Suspension

Open-Angle GlaucomaOcular Hypertension

The purpose of the study is to compare the safety and intraocular pressure-lowering efficacy of AL-37807 ophthalmic suspension vs. Timolol gel forming solution vs. AL-37807 vehicle, all dosed concomitantly with Xalatan, in patients with open-angle glaucoma or ocular hypertension.

Completed7 enrollment criteria

Safety and Efficacy of PF-04217329 in Patients With Glaucoma or Elevated Eye Pressure.

Primary Open-Angle GlaucomaOcular Hypertension

To evaluate the safety and efficacy of PF-04217329.

Completed4 enrollment criteria

Safety and Efficacy Study of Brimonidine/Timolol Fixed Combination in Patients With Glaucoma or...

GlaucomaOcular Hypertension

This study evaluates the safety and efficacy of brimonidine 0.2%/timolol 0.5% fixed combination ophthalmic solution compared with concurrent brimonidine 0.2% and timolol ophthalmic solutions

Completed4 enrollment criteria

Safety and Efficacy Study of DE-104 Ophthalmic Solution to Treat Open-angle Glaucoma or Ocular Hypertension...

Open-Angle GlaucomaOcular Hypertension

To investigate the dose-response relationship of DE-104 ophthalmic solution in lowering intraocular pressure (IOP) in subjects with Primary Open-Angle Glaucoma or Ocular Hypertension

Completed6 enrollment criteria

Travoprost New Formulations in Patients With Open-Angle Glaucoma or Ocular Hypertension

Ocular HypertensionOpen-angle Glaucoma

The purpose of this study was to describe the safety and IOP-lowering efficacy of Travoprost New Formulations compared to TRAVATAN® and to vehicle in patients with open-angle glaucoma or ocular hypertension.

Completed16 enrollment criteria

Patient Preference Comparison of AZARGA Versus COSOPT

Open-Angle GlaucomaOcular Hypertension

The purpose of this study was to assess patient preference regarding ocular comfort of AZARGA® compared to COSOPT® after one week instillation of each study medication.

Completed20 enrollment criteria

Latanoprost Versus Tafluprost: 24-hour Intraocular Pressure (IOP)

Primary Open Angle GlaucomaOcular Hypertension

Main objective is to compare the ability of Latanoprost 0.005% preservative-added ophthalmic solution versus Tafluprost 0.0015% preservative-free ophthalmic solution, both given once a day at the evening, in reducing 24-hour intraocular pressure (IOP) in patients with primary open angle glaucoma (POAG) and/or ocular hypertension (OHT) at first diagnosis. First efficacy variable will be the difference between mean nocturnal IOP values after three months of treatment: nocturnal IOP is defined as the mean value between 2AM and 6AM measurements. Secondary objectives will be the comparison between Latanoprost 0.005% and Tafluprost 0.0015% ophthalmic solution about: Mean 24-hour IOP values after three months of treatment IOP values at these time-points: 10AM (± 1 hour), 2PM (± 1 hour), 6PM (± 1 hour), 10PM (± 1 hour), 2AM (± 1 hour) and 6AM (± 1 hour) after three months of treatment

Completed10 enrollment criteria

DE-111 Against Tafluprost Ophthalmic Solution 0.0015% Alone and Concomitant Use of Tafluprost Ophthalmic...

Open Angle GlaucomaOcular Hypertension

DE-111 ophthalmic solution will be evaluated for superiority in comparison with Tafluprost 0.0015% ophthalmic solution, or for non-inferiority in comparison with Tafluprost 0.0015% and Timolol ophthalmic solution 0.5% used concomitantly, in IOP(intraocular pressure) -lowering effect in primary open-angle glaucoma or ocular hypertension patients, in a multicenter, randomized, double-masked, parallel-group comparison study. Safety will be compared and evaluated as well.

Completed6 enrollment criteria

A 12-Month Study to Evaluate the Efficacy and Safety of Once-Daily Instillation of Combination Glaucoma...

GlaucomaOpen-angle1 more

The purpose of this study is to evaluate the intraocular pressure(IOP)-lowering efficacy of a combination IOP-lowering therapy in patients with open-angle glaucoma or ocular hypertension.

Completed2 enrollment criteria
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