Evaluation of Regulation Focused Psychotherapy for Children
Oppositional Defiant DisorderOppositional Defiant Disorder in ChildrenThe main objective of this project is to conduct a study of RFP-C for children with disruptive behaviors. Regulation Focused Psychotherapy for Children (RFP-C) is a twice a week, play therapy intervention.
Task-Based Grounding Program
AggressiveDefiant Disorder2 moreThe purpose of this study is to improve the availability of brief interventions to help children with defiant, aggressive and disruptive behaviors by creating a brief scalable intervention for parents delivered via telehealth. As phase 1 study, we are conducting a 2-arm pilot feasibility RCT in order the intervention, measures, and procedures to be used in a larger efficacy trial. The first arm will include a 3-session behavioral therapy treatment we call Task-Based Grounding and the second arm will be an enhanced treatment as usual comparison group.
Supplements and Social Skills Intervention Study
Conduct DisorderAttention Deficit Hyperactivity Disorder1 moreThis is a 36-week, randomised, double-blind, placebo-controlled trial. The overarching aim of this study is to assess whether a nutritional intervention (Omega-3 supplement), when combined with a more traditional treatment approach to conduct disorder and Attention Deficit Hyperactivity Disorder (ADHD), is more effective than either approach alone in treating these conditions in children and adolescents. The research questions cannot be answered through alternative means because disruptive behaviour disorders are primarily childhood disorders.
A Study of the Safety and Effectiveness of Risperidone for the Treatment of Conduct Disorder and...
Conduct DisorderOppositional Defiant Disorder1 moreThe purpose of the study is to assess the safety and effectiveness of oral risperidone (an antipsychotic medication) in the treatment of conduct disorder and other disruptive behavior disorders in children ages 5 to 12 with mild, moderate, or borderline mental retardation.
Divalproex Sodium (Depakote) for Explosive Tempers in Adolescents and Adults
Attention Deficit and Disruptive Behavior DisordersMarijuana AbuseThe purpose of this study is to compare the effectiveness of divalproex sodium (Depakote) versus placebo in treating disruptive behavior disorder and explosive tempers in adolescents and adults.
Metabolic Effects of Antipsychotics in Children
AggressionAttention Deficit-Hyperactivity3 moreThe project aims to describe and compare the outcome of 12 weeks of prospective, randomized treatment with olanzapine, risperidone or aripiprazole on insulin action in skeletal muscle, liver and adipose tissue, abdominal fat mass, total body and fat-free mass, efficacy for symptoms of aggression and non-metabolic adverse events. Children aged 6-18 will be studied, exploring effects of stimulant therapy and age-related differences in vulnerability to treatment-induced adverse metabolic changes. Aims are addressed by measuring glucose and lipid kinetics with stable isotope tracers, body composition with dual energy x-ray absorptiometry and magnetic resonance imaging (MRI), and standardized assessments of efficacy and adverse events. Relevant data are critically needed to target clinical therapy and basic research, identify medical risks, and guide regulatory decisions in this vulnerable population.
Multi-Family Group Therapy for Reducing Behavioral Difficulties in Youth
Oppositional Defiant DisorderConduct DisorderThis study will examine the effectiveness of a multiple family group mental health service delivery strategy in improving mental health service use and outcome for urban, low income children of color, ages 7-11 years old with disruptive behaviors and their families.
Comparison of Two Psychosocial Therapies for Treating Children With Oppositional-Defiant Disorder...
Oppositional-Defiant DisorderThis study will evaluate the effectiveness of two different psychosocial therapies, parent management training and collaborative problem solving, in treating children with oppositional-defiant disorder.
The Effect of Occupational Therapy on Subthreshold Attention Deficit Hyperactivity Disorder
Attention Deficit and Disruptive Behavior DisordersThe purpose of this study is to investigate the effectiveness of occupational therapy in subthreshold attention deficit hyperactivity disorder.
Addressing Behaviour and Treatment Effectiveness Project (A.B.A.T.E. Project)
Disruptive Behavior DisorderThis study investigates the effectiveness of a clinic-adapted version of the Coping Power program compared to individualized child and family treatment for children with disruptive behaviour and their parents.