Medial-Wedge Insole is Highly Effective in the Treatment of Valgus Knee Osteoarthritis
OsteoathritisTo assess the efficacy of medial-wedge insole in valgus knee osteoarthritis (OA). We hypothesized that medial-wedged insoles are biomechanically effective and should reduce lateral compartment loading in persons with valgus knee osteoarthritis with a consequent symptomatic improvement.
Study of Ampion for the Treatment of Pain and Function in Patients With Severe Osteoarthritis of...
Severe Osteoarthritis of the KneeThe purpose of this study is to confirm the safety and efficacy of Ampion for the treatment of pain and function in patients with severe osteoarthritis of the knee.
Vanguard Rocc Post Market Surveillance
OsteoarthritisKnee7 moreThe objective of this project is to obtain prospective, multi-center, long term (10 year) clinical data on the Vanguard Rocc knee prosthesis. Patient and knee function will be collected along with knee stability, the knee motion, functional recuperation, radiographic and survivorship data.
Routine Application of Ostenil® in Patients With Gonarthrosis
GonarthrosisPMCF study to observe the routine application of Ostenil® in the treatment of pain and restricted mobility in degenerative and traumatic changes of the knee joint.
Study to Evaluate Long Term Performance and Safety of the Knee Prosthesis (HLS KneeTec Deep Dish)...
Total Knee ArthroplastyKnee Disease2 moreThe aim of this study is to assess the long-term performance and safety of HLS KneeTec Deep Dish knee prosthesis when used in standard medical practice
Evaluate the Efficacy and Safety of ACP-044 in Subjects With Pain Associated With Osteoarthritis...
Osteoarthritis PainTo evaluate the efficacy of ACP-044 compared with placebo in the treatment of pain associated with osteoarthritis of the knee
Gait Modification for Knee Osteoarthritis
OsteoarthritisKneeThis randomized clinical trial will compare the changes in performance, biomechanical and clinical outcomes before and after a six-week gait modification intervention. Participants with knee osteoarthritis will attend in-lab assessments and practice, while also performing daily, at-home walking tracked using a custom sensorized shoe.
FibroFix Cartilage P Knee Implant Study
OsteoarthritisKneeThis is a multi-center first-in-human prospective clinical investigation to evaluate the safety and performance of the FibroFix™ Cartilage P Implant and Drill Set. The Implant is a medical device designed by Orthox Ltd. to repair a damaged area of cartilage within the knee joint. The aim is to 75 participants over two Stages: In STAGE I, up to a total of 6 subjects will be recruited and safety assessed after 6 months of follow-up. In Stage II an additional 69 subjects. The subjects will be followed up for 2 years with MRI imaging, then a further 8 years with patient outcome questionnaires.
Axial Alignment in Patients Operated Using the Visionaire Patient Matched Cutting Blocks
Osteoarthritis of the Knee- Title: PATIENT-MATCHED INSTRUMENTATION VS. STANDARD INSTRUMENTATION: A RANDOMIZED CLINICAL TRIAL COMPARING POSTOPERATIVE AXIAL ALIGNMENT and COMPONENT POSITION Short Title: Visionaire Alignment Methodology: Monocentric, Single Blinded, Randomized Controlled Trial Study Duration: November 2010 to July 2014 Study Centres: Leicester General Hospital, United Kingdom (UK)
A Safety and Tolerability Study of JNJ-42160443 in Patients With Moderate to Severe, Chronic Knee...
OsteoarthritisOsteoarthritis4 moreThe purpose of this study is to evaluate pain relief, safety, and tolerability of a new treatment (JNJ-42160443) for moderate to severe pain of osteoarthritis of the knee in comparison to a standard pain treatment and placebo.