Active clinical trials for "Pancreatic Diseases"

The objectives of this project are to test whether alteration in DNA hypermethylation in plasma is: a diagnostic marker for pancreatic cancer a prognostic marker for pancreatic cancer a marker for recurrence of pancreatic cancer changing during the course of chronic pancreatitis, with the purpose of finding patients with high risk of developing pancreatic cancer

Distal pancreatectomy is the surgical technique performed to treat many pancreatic diseases located in neck and tail of the pancreas. Laparoscopic approach is the gold standard but in many centres the percentage of laparoscopic approach is still low. This technique has low mortality but 30% morbidity mostly related to pancreatic fistula. Some new devices (linear stapler, energy devices and patches) seem to decrease pancreatic fistula but there is not evidence based medicine that confirm the results published usually in unicentric studies.