A Study of Baricitinib (LY3009104) in Children From 6 Years to Less Than 18 Years of Age With Alopecia...
Areata AlopeciaAlopecia5 moreThe main purpose of this study is to determine the efficacy and safety of baricitinib for the treatment of severe or very severe alopecia areata (hair loss) in children from 6 years to less than 18 years of age. The study is divided into 4 periods, a 5-week Screening period, a 36-week Double-Blind Treatment Period, an approximately 2-year Long-term Extension Period, and a 4-week Post-treatment Follow-up period.
Impact of Postprandial 'Exercise Snacks' on Protein and Glucose Metabolism Following a Period of...
InactivityPhysical10 moreThe purpose of this study is to assess the impact of 3-days reduced physical activity (<1500 steps/day) with/without 'exercise snacks' (15 chair stands with calf raises every 30 min) on skeletal muscle metabolic health.
3D Resin Printed Fracture Models for Anatomy Education
Educational ProblemsAnatomical Pathological ConditionResin printing is an emerging technology with a wide array of applications. This research seeks to assess the practicality of incorporating 3D resin printed models into anatomy education while investigating how fractured models impact students' decision-making and quiz scores.
T-GENVIH-003 LTFU (Long Term Follow Up) Study
HerniaHernia5 moreThe T-GENVIH-003 study will collect additional, longer term performance data of Gentrix® Surgical Matrix used for reinforcement of ventral hernia repairs from a subset population (i.e., the twenty-one minimally invasive surgical approach cases) from the prior T-GENVIH-002 study.
Mitroflow DL Post Approval Study- North America
Aortic StenosisAortic Regurgitation8 moreProspective, non-randomized, multicenter post-approval study to collect long term clinical and echographic data on Mitroflow DL patients.
Comparison of Amnion Chorion Membrane vs. Dense Polytetrafluoroethylene Membrane in Ridge Preservation...
Alveolar Bone LossPathological Conditions1 moreThe purpose of this study is to examine if a biologically active commercially available amnion chorion membrane (ACM) is as effective as the commercially available inert dense polytetrafluoroethylene membrane (D-PTFE) in preserving jaw bone dimensions and whether it provides the added benefit of reducing post-operative discomfort after dental surgery
'TOTAL' (Tracheal Occlusion To Accelerate Lung Growth) Trial
HerniaHernia11 moreThis trial will test whether temporary fetoscopic endoluminal tracheal occlusion (FETO) rather than expectant management during pregnancy, followed by standardized postnatal management, increases survival at discharge and decreases oxygen need at 6 months in case of survival till discharge.
GORE Flow Reversal System and GORE Embolic Filter Extension Study
Carotid StenosisConstriction11 moreThe objective of this study is to provide an ongoing evaluation of clinical outcomes associated with the GORE Flow Reversal System and the GORE Embolic Filter when used for embolic protection during carotid artery stenting.
BowelScope: Accuracy of Detection Using ENdocuff Optimisation of Mucosal Abnormalities
Colorectal NeoplasmsColonic Polyp14 moreThis study aims to assess the effect, if any, on the adenoma detection rate of BowelScope bowel cancer screening flexible sigmoidoscopies by using the Endocuff Vision device.
Visualization of the Extrahepatic biliaRy Tree Trial
CholecystitisAcute10 moreThis study is a prospective randomized controlled trial evaluating the use of a fluorescent dye, indocyanine green (ICG), in the identification of important bile duct anatomy during emergent same-admission cholecystectomy. Participants will be randomized into either the control arm, which uses the standard of care white light during laparoscopy or the intervention arm, which will use ICG fluorescent cholangiography as an adjunct to white light to visualize the biliary anatomy. The investigators hypothesize that the use of fluorescent cholangiography will increase the rates of identification of important biliary anatomy during laparoscopic cholecystectomy. The effectiveness, feasibility, and safety will be compared between the two groups using a post-operative survey form the surgeons will complete prior to exiting the operating room.