
Efficacy, Safety, Tolerability of Vabomere Compared to Best Available Therapy in Treating Serious...
Urinary Tract Infection ComplicatedAcute Pyelonephritis4 moreVabomere™, (meropenem-vaborbactam) is being compared to the Best Available Therapy in the treatment of adults with selected serious infections due to Carbapenem Resistant Enterobacteriaceae

Trial of Colistin Versus Meropenem in Ventilator-associated Pneumonia (VAP) (CR-GNB)
Ventilator-associated Bacterial PneumoniaTo demonstrate that colistin iv. is not inferior to meropenem in empiric treatment of VAP regarding the final point of primary efficacy: mortality in the 28 subsequent days and clinical healing in patients clinically evaluated. To compare the safety of treatment with colistin vs meropenem in VAP. To compare microbiological efficacy of treatment with colistin vs meropenem in VAP

The Study of Unasyn-S 12g/Day for Community Acquired Pneumonia (CAP)
PneumoniaBacterialUnasyn-S 12g/day (3 g four times a day) is the commonly used dosage depending on the severity for US, EU, China, Taiwan and Korea for over 20 years, however, Unasyn-S 12g/day has not yet been approved in Japan. The purpose of this trial is to evaluate the clinical efficacy and safety in Japanese adult subjects with community acquired pneumonia receiving ampicillin sodium/sulbactam sodium, 12g/day (3 g four times a day ) IV.

Comparative Study of Ceftaroline vs. Ceftriaxone in Adult Subjects With Community-Acquired Pneumonia...
Bacterial PneumoniaThe purpose of this study is to determine whether ceftaroline is effective and safe in the treatment of Community-Acquired Pneumonia

A Safety and Tolerability Study of Doripenem in Patients With Abdominal Infections or Pneumonia...
PneumoniaVentilator-Associated5 moreThe purpose of this study is to assess the safety and tolerability of doripenem compared to imipenem in Ventilator-assisted pneumonia and complicated Intra-abdominal Infection. The study population will include hospitalized patients (or patients resident in a chronic health care facility) who have a diagnosis of either Ventilator associated pneumonia or complicated Intra-abdominal Infection.

Comparison of Telavancin and Vancomycin for Hospital-acquired Pneumonia Due to Methicillin-resistant...
Bacterial PneumoniaStudy 0015 (NCT00107952) compares the safety and effectiveness of an investigational drug, telavancin, with vancomycin for the treatment of hospital-acquired pneumonia.

Comparison of Telavancin and Vancomycin for Hospital-acquired Pneumonia Due to Methicillin-resistant...
Bacterial PneumoniaStudy 0019 (NCT00124020) compares the safety and effectiveness of an investigational drug, telavancin, with vancomycin for the treatment of hospital-acquired pneumonia.

Study to Evaluate the PK of PO Omadacycline in Adults With Community-Acquired Bacterial Pneumonia...
Community-acquired PneumoniaThe purpose of this study is to evaluate the pharmacokinetics of an oral omadacycline dosing regimen in the treatment of adults with CABP.

Search for Biomarkers of Infection and Inflammation in Patients With Acute Stroke.
StrokeAcute2 moreThis study will look for new biomarkers of infection and evaluate current biomarkers of infection in stroke patients. Patients with acute stroke will be monitored with daily blood samples for seven days and by clinical examination to detect infections for 10 days.

Study to Evaluate the Efficacy and Safety of Intravenous Sulbactam-ETX2514 in the Treatment of Patients...
Acinetobacter Baumannii-calcoaceticus ComplexHospital-acquired Bacterial Pneumonia3 moreThis is a 2-part study, with Part A being the randomized, controlled portion of the study in patients with ABC hospital-acquired bacterial pneumonia (HABP), ventilator-associated bacterial pneumonia (VABP), or bacteremia. Part B is the single-group portion of the study and includes ABC infections that are resistant to or have failed colistin or polymyxin B treatment, as detailed in the inclusion criteria.