Study to Evaluate Safety and Efficacy of PreCrea® on Subjects With Higher Than Normal Blood Sugar...
Diabetes MellitusPre-Diabetes2 moreThe purpose of the study is to evaluate the efficacy and safety of PreCrea® on subjects with higher than normal blood sugar levels.
Safety & Effectiveness on Vascular Structure and Function of ACZ885 in Atherosclerosis and Either...
Diabetes MellitusType 22 moreThis study will evaluate the effect of ACZ885 on vascular function in patients with documented atherosclerotic disease and T2DM or IGT.
Physical Exercise Versus Rosiglitazone in CAD and Prediabetes
Impaired Glucose ToleranceThe aim of this study is to prospectively assess the relative benefits of either treatment with rosiglitazone or physical exercise on endothelial function in patients with impaired fasting glucose or impaired glucose tolerance and coronary artery disease (CAD).
A Study to Evaluate the Effects of Vildagliptin on the Insulin Response to Glucose in Subjects With...
Pre-diabetesThis is an exploratory study to assess whether vildagliptin, an unapproved drug, can increase insulin secretion in subjects with pre-diabetes who have a defect in the insulin response and elevated levels of fasting glucose.
Chromium Picolinate for the Treatment of Metabolic Syndrome
Metabolic Syndrome XPrediabetic State3 moreThe purpose of this study is to determine whether chromium supplements can reduce symptoms of metabolic syndrome, a collection of symptoms that increase one's risk for developing heart disease, stroke, and diabetes.
Efficacy and Safety of Vildagliptin in Subjects With Impaired Glucose Tolerance
Prediabetic StateThe purpose of this study is to assess the safety and effectiveness of vildagliptin, an unapproved drug, compared to placebo in lowering post-meal blood glucose levels in people with pre-diabetes who have high blood sugar levels after meals.
Treating the Endothelium to Restore Insulin Sensitivity
ObesityInsulin Resistance2 moreA study of 12 weeks' treatment with losartan or placebo, to test the hypothesis that RAS inhibition will improve insulin' vascular actions and therefore improve insulin sensitivity in skeletal muscle.
Stanford Kids CAMP Study
Pre-diabetesObesity1 moreThe Stanford Kids CAMP study aims to evaluate the feasibility of enrolling minority participants in school age children (5-13 years old) in a community summer camp setting along with the efficiency by which each participant's biologic specimens are collected. Using remote monitoring technologies and through partnering with community-based organizations, the investigators hypothesize that an increase in underrepresented minority participation in a clinical trial that is greater than the national average is possible.
Emotional Awareness and Expression Therapy for Prediabetes
PreDiabetesThis feasibility study seeks to develop and pilot test Emotional Awareness and Expression Therapy as a possible treatment for people with prediabetes.
Linagliptin Response to OGTT in Prediabetes and Type 2 Diabetes Mellitus
PreDiabetesType 2 DiabetesThere are studies that suggest glycemic response to incretin-based therapies differs between Asians and Caucasians, whereby Asians have better response compared to Caucasians. Hence, the therapeutic response could also be augmented by difference in incretin system among various ethnicities. This study is carried out to study the effect of dipeptidyl-peptidase IV (DPPIV) inhibitors in prediabetes and T2DM patients who have different levels of GLP-1 and to determine the effect on glycemic profiles, insulin resistance/sensitivity, beta-cell functon.