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Active clinical trials for "Psoriasis"

Results 881-890 of 1714

Efficacy and Safety Study of Guselkumab in the Treatment of Participants With Moderate to Severe...

Psoriasis

The purpose of the study is to evaluate the efficacy, safety, pharmacokinetics, immunogenicity, usability, and acceptability of guselkumab delivered using SelfDose device in participants with moderate to severe plaque-type psoriasis.

Completed10 enrollment criteria

An Open Label, Safety Study to Assess the Potential for Adrenal Suppression

Plaque Psoriasis

An Open Label, Safety Study to Assess the Potential for Adrenal Suppression Following Treatment with DSXS (Taro Pharmaceuticals U.S.A., Inc.) in Patients with Plaque Psoriasis

Completed2 enrollment criteria

A Study to Evaluate the Efficacy and Safety of Bimekizumab in Adult Subjects With Moderate to Severe...

Chronic Plaque PsoriasisModerate to Severe Plaque Psoriasis

This is a study to compare the efficacy of bimekizumab versus adalimumab in the treatment of subjects with moderate to severe chronic plaque psoriasis (PSO).

Completed14 enrollment criteria

Brodalumab in Subjects With Moderate to Severe Plaque Psoriasis Who Have Failed IL-17A Therapies...

Psoriasis

This study will evaluate the safety and efficacy of brodalumab in the treatment of moderate-to-severe psoriasis in patients who have previously failed treatment with interleukin (IL)-17A therapies. Forty patients will be enrolled in this 16-week open-label study. Patients will receive 210 mg of brodalumab subcutaneous injection at weeks 0, 1, and 2, followed by 210 mg every 2 weeks. The primary efficacy endpoint will be the proportion of patients achieving a score of "0-clear" or "1-almost clear" in the sPGA score after 16 weeks of treatment. After completion of the 16-week trial, patients may desire to continue treatment with brodalumab.

Completed30 enrollment criteria

Risankizumab Therapy Versus Placebo for Subjects With Psoriasis in the Russian Federation

Psoriasis

The purpose of this study is to assess the safety and efficacy of risankizumab compared to placebo in subjects with moderate to severe chronic plaque psoriasis in the Russian Federation.

Completed5 enrollment criteria

Effect of Vitamin D Supplementation on Metabolic Parameters of Patients With Psoriasis

PsoriasisMetabolic Syndrome1 more

The purpose of this study is to determine whether supplementation with oral vitamin D (cholecalciferol) improves metabolic parameters in patients with moderate to severe psoriasis.

Completed7 enrollment criteria

Study to Assess the Immunogenicity and Safety of Etanercept Produced Using a Modified Process in...

Plaque Psoriasis

The purpose of this study is to learn more about the immune response to etanercept produced using a modified process in patients with plaque psoriasis.

Completed22 enrollment criteria

A Study in Japanese Participants With Moderate-to-Severe Psoriasis

Psoriasis

This study will assess the safety and efficacy of ixekizumab in participants with moderate to severe psoriasis in Japan.

Completed15 enrollment criteria

Safety and Efficacy Study of Adalimumab in the Treatment of Plaque Psoriasis

Plaque Psoriasis

A study to evaluate the safety and efficacy of adalimumab in Chinese subjects with moderate to severe plaque psoriasis.

Completed10 enrollment criteria

A Study in Participants With Moderate to Severe Psoriasis (UNCOVER-3)

Psoriasis

This study will assess the safety and efficacy of ixekizumab (LY2439821), compared to etanercept and placebo in participants with moderate to severe chronic plaque psoriasis.

Completed17 enrollment criteria
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