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Active clinical trials for "Gastroesophageal Reflux"

Results 821-830 of 878

Near Focus NBI-Driven Artificial Intelligence for the Diagnosis of Gastro-Oesophageal Reflux Disease...

Gastro Esophageal Reflux

Gastro-oesophageal reflux disease (GORD) is a chronic condition with symptoms arising secondary to the reflux of stomach contents (Vakil et al., 2006). It is divided into four phenotypes: Erosive Oesophagitis (EO), Non-Erosive Reflux Disease (NERD), Reflux Hypersensitivity (RH), Functional Heartburn (FH) (Nikaki, Woodland and Sifrim, 2016). The definition of these phenotype have evolved with the addition of diagnostic tests and methods of their interpretation, the most recent being the Lyon Consensus Statement (Gyawali et al., 2018). The majority of patients presenting with symptoms suggestive of GORD have no mucosal lesion seen at endoscopy (Nikaki, Woodland and Sifrim, 2016). Studies have shown a relation of increased IPCL numbers with GORD. This study aims to build a fully autmoated AI model using Near-Focus NBI images on patients with symptoms suggestive of GORD phenotyped in accordance with the Lyon Consensus.

Completed8 enrollment criteria

Anthropometric Measures and Severity of Gastroesophageal Reflux Disease

Gastroesophageal Reflux Disease

evaluate the impact of different anthropometric measures on clinical and endoscopic severity of GERD and its relation to serum leptin.

Completed6 enrollment criteria

Mucosal Impedance in Pediatric Population

Gastroesophageal Reflux Disease (GERD)Eosinophilic Esophagitis (EoE)1 more

Our hypothesis is that patients with GERD and/or Eosinophilic Esophagitis (EE) have lower esophageal impedance measurements when compared to patients who do not have GERD or EE.

Completed4 enrollment criteria

Analysis of Biopsies From the Upper Gastrointestinal Tract

Gastroesophageal Reflux DiseaseGastritis

Multicenter study to correlate histological findings in the upper gastrointestinal tract with endoscopic and clinical data.

Completed2 enrollment criteria

Confocal Endomicroscopy for Permeability of Esophageal Wall in Refractory Gastroesophageal Reflux...

Gastro Esophageal RefluxBarrett Esophagus1 more

Confocal Endomicroscopy for Permeability of Esophageal Wall in Refractory Gastroesophageal Reflux Disease (GERD)

Unknown status8 enrollment criteria

Nexium Capsules S-CEI for Justification of Esomeprazole in Acid Related Disease for Reflux Symptom...

Reflux Esophagitis

The objective of this investigation is to collect following data in patients given NEXIUM capsule (NEXIUM) in usual post-marketing use.

Completed11 enrollment criteria

Pepsin As A Biomarker For Aspiration

AspirationGastroesophageal Reflux

Evaluation of tracheal pepsin as a biomarker for aspiration

Completed3 enrollment criteria

Survey to Describe Impact of Reflux Disease on Everyday Life in GERD Patients Before and After 4...

Gastroesophageal Reflux Disease

To describe the change of impact of reflux symptoms on the everyday life perceived by patients before and after 4 weeks treatment by using GERD Impact Scale questionnaire (GIS) by total GERD patient population and by treatment group; and to describe the concordance between patient-reported and physician-reported symptom load.

Completed4 enrollment criteria

Partial Response to PPI Treatment: The Cost to Society and the Burden to the Patient - a Study in...

Gastroesophageal Reflux Disease

The purpose of this study is to describe common treatment pathways, to collect health care utilization data and to assess symptom load as well as impact of symptoms on daily life in GERD patients who are partial-responders to PPI treatment.

Completed8 enrollment criteria

Gastroesophageal Reflux Disease (GERD) Segmentation: Document How Swiss General Practitioners (GPs)...

GERD

Document how Swiss GPs allocate their GERD patients to the three GERD patient segments (according to King et al.) and how treated GERD patients are affected by their GERD treatment

Completed3 enrollment criteria
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