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Active clinical trials for "Kidney Failure, Chronic"

Results 891-900 of 1823

More Frequent Dialysis (>3 Treatments Per Week)

End Stage Renal DiseaseChronic Kidney Disease

The study compares the benefits of short daily hemodialysis six days a week, nocturnal (night time) hemodialysis six days a week, every other day and every other night hemodialysis to traditional three days a week hemodialysis.The hypothesis is that increasing hemodialysis treatment time and/or frequency will improve outcomes.

Completed9 enrollment criteria

Effects of Oral Cholecalciferol (Vitamin D3) on Bone Health, Neuromuscular Function, and Quality...

End Stage Renal Disease

Will oral vitamin improve strength, bone quality, pain and quality of life. This is a double blind, randomized placebo controlled study using 10,000 IU of cholecalciferol vs placebo.

Completed5 enrollment criteria

A Research Study for Patients With End-Stage Renal Disease (ESRD)

End Stage Renal Disease

The purpose of this study is to evaluate the ability of a treatment strategy, that includes cinacalcet for the management of secondary hyperparathyroidism, to control parathyroid hormone (PTH) compared with the standard of care.

Completed9 enrollment criteria

Effects of Cyclosporine A on Pancreatic Insulin Secretion

Chronic Renal Failure

Our primary aim is to investigate if cyclosporine A reduces insulin secretion.

Completed11 enrollment criteria

Muscle Status to Oral Nutritional Supplementation in Hemodialysis Patients With Protein Energy Wasting...

Muscle WastingEnd Stage Renal Disease on Dialysis

This multi-centred randomized, open label-controlled trial consists of hemodialysis (HD) patients identified with protein energy wasting (PEW) using the International Society of Renal Nutrition and Metabolism criteria. Intervention provided was oral nutritional supplementation (ONS) for 6 months and changes in muscle status in response toward the treatment was measured using ultrasound imaging method pre- and post-intervention.

Completed8 enrollment criteria

Home-based vs Intradialysis Exercise Guided by Nursing Staff

End Stage Renal Disease on Dialysis

Participants will be randomized either to home-based exercise or to intradialysis exercise guided by nurses of the renal unit. The programs will last 16 weeks. The intradialysis exercise consists of combined aerobic and resistance training exercise. The home-based exercise consists of resistance exercise and walking.

Completed8 enrollment criteria

Can Dietitians Reduce Interdialytic Weight Gain in at Risk Hemodialysis Patients Through Tailored...

End Stage Renal Disease Requiring Hemodialysis

The purpose of this project is to understand if more frequent education of dialysis patients (patients with kidney failure who get their blood cleaned and fluid removed by a machine instead of their kidneys) on reducing sodium intake reduces the amount of fluid weight that patients gain between dialysis sessions. Patients who usually gain more fluid than is considered ideal will be recruited for this project. Because all patients gain different amounts to start, data will be collected for 3 months while the patients receive their usual amount of dietitian education. Then the patients will receive intensive (2x/month) education on reducing sodium intake from the dietitian and the same data will be collected to see if they gain less after the education. After 3 months of intensive education, data will be collected for one more month to see if patients keep gaining less or if they go back to their old patterns.

Completed10 enrollment criteria

Coronary Artery Disease Screening in Kidney Transplant Candidates

End Stage Renal DiseaseCoronary Artery Disease

Kidney transplant candidates are at very high risk for coronary artery disease (CAD). The optimal strategy to monitor and maintain the cardiac fitness of patients awaiting kidney transplantation is unknown. Currently patients undergo annual testing; however, screening for CAD may increase morbidity and mortality by: exposing patients to the risk of angiography and revascularization procedures delaying or excluding patients from life saving transplantation. Before proceeding with a definitive study to determine whether screening is necessary, feasibility will be determined in this pilot study.

Completed9 enrollment criteria

Use Of Fragmin In Hemodialysis

Chronic Renal Failure

The study will determine if the Fragmin dose can be adjusted to suit the clinical needs of patients during dialysis.

Completed2 enrollment criteria

Solute Removal With High Volume Hemodiafiltration Versus Long High Flux Hemodialysis

End-stage Renal Disease

This is a prospective cross-over study including 10 stable hemodialysis patients with chronic kidney disease stage 5. The cross-over study lasts 2 weeks with the study dialysis sessions at midweek. During one session, the patient will be dialyzed during 4 hours with high volume post dilution hemodiafiltration (HDF) with an FX800 hemodialyzer (Fresenius Medical Care) and a blood flow of 300mL/min, dialysate flow of 500mL/min, and substitution flow of 75mL/min. During the other midweek session, the patient will be dialyzed during 8 hours with high flux hemodialysis (HD) with an FX80 hemodialyzer (Fresenius Medical Care) and a blood flow of 200mL/min and a dialysate flow of 500mL/min. The HDF and HD sessions will be randomized. Blood samples will be drawn pre and post dialysis from the arterial blood line, and after 30min after dialysis start, a blood sample will be drawn from the inlet and outlet line. At the dialysate outlet line, partial dialysate collection is performed at the outlet line. Blood and dialysate samples will be analyzed for a broad range of retention solutes like small and water soluble solutes, middle molecules, and protein bound solutes. These data will be further used to calculate solute removal and evaluate any differences between the solute removal during high volume post dilution HDF and high flux HD.

Completed10 enrollment criteria
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