
Studying Protein Expression in Tissue Samples From Younger Patients With Rhabdomyosarcoma
Alveolar Childhood RhabdomyosarcomaEmbryonal Childhood Rhabdomyosarcoma3 moreThis research trial studies protein expression in tissue samples from younger patients with rhabdomyosarcoma. Studying samples of tissue from patients with cancer in the laboratory may help doctors learn more about changes that occur in DNA and identify biomarkers related to cancer. It may also help doctors find better ways to treat cancer.

Evaluation, Treatment, and Natural History of Children and Young Adults With Cancer or Rare Diseases...
Ewing's SarcomaLeukemia3 moreThis protocol is designed to evaluate children with cancer who appear to be probable candidates for future protocol entry or have disease manifestations that are of unique scientific importance or educational value.

Collecting Tumor Samples From Patients With Gynecological Tumors
Borderline Ovarian Clear Cell TumorBorderline Ovarian Serous Tumor85 moreThis laboratory study is collecting tumor tissue and blood samples from patients with gynecologic tumors. Collecting and storing samples of tumor tissue and blood from patients with cancer to study in the laboratory may help in the study of cancer.

Elucidating the Genetic Basis of the Pleuropulmonary Blastoma (PPB) Familial Cancer Syndrome
Pleuropulmonary BlastomaCystic Nephroma8 morePleuropulmonary Blastoma (PPB) is a rare lung tumor which develops in childhood. The underlying genetic factors which contribute to the development and progression of PPB are not defined. We are working to identify the genetic factors which may contribute to the development of this rare tumor.

EpSSG (European Soft Tissue Sarcoma Study Group) Protocol for Non-Metastatic Rhabdomyosarcoma in...
RhabdomyosarcomaThe purpose of the study is achieve standardization treatment of low and intermediate risk rhabdomyosarcoma patients, with an attempt to improve treatment results in high and very high risk patients by the addition of doxorubicin as induction treatment and at the maintenance phase.

Trabectedin and Irinotecan for Refractory Pediatric Sarcomas
Recurrent Childhood Soft Tissue SarcomaRecurrent Ewing Sarcoma1 moreThe purpose of the study is to evaluate patients with refractory childhood sarcomas, who have been treated with a combination therapy of trabectedin and irinotecan (within compassionate use), to determine, if this is a promising treatment option with acceptable toxicity and if the results warrant a prospective study.