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Active clinical trials for "Sarcoma"

Results 1381-1390 of 1445

AIDS and Cancer Specimen Bank (ACSB)

Kaposi's Sarcoma AIDS RelatedKaposi's Sarcoma Classical4 more

The purpose of this study is to obtain clinical specimens from pathologists and physicians involved in the diagnosis and care of patients with AIDS and non-AIDS associated malignancies. The National Cancer Institute has set up a Bank for tissues and biological fluids from HIVpositive and HIV-negative individuals in order to have specimens available for scientists studying malignancies associated with HIV disease.

Completed5 enrollment criteria

GENSARC 2008 : Medical Economic Evaluation of the Molecular Detection by FISH (Fluorescent in Situ...

Sarcoma

The clinical and histological diagnosis of sarcomas is often very difficult. The identification of chromosomal and molecular anomalies, such as amplifications, deletions or fusion genes is a powerful help for establishing a correct diagnosis of sarcomas and their benign counterparts. However, the cost of the cytogenetic and molecular techniques for the detection of these alterations is often a limitation to their use. The aim of our study is to evaluate the direct cost of the molecular techniques in comparison to the cost that would be generated by an appropriate therapy and care management of the patient in case of an erroneous diagnosis.

Completed5 enrollment criteria

A Study to Provide Access to Trabectedin in Participants With Locally Advanced or Metastatic Soft...

Sarcoma

The purpose of this study is to facilitate access to trabectedin for eligible previously treated patients with soft tissue sarcoma (STS), who cannot be expected to benefit from currently available therapeutic options but who may benefit from treatment with trabectedin. The safety profile of trabectedin will be evaluated to further assess the potential risks of trabectedin treatment.

No longer available10 enrollment criteria

US-Guided Biopsy in the Diagnosis of Musculoskeletal Soft-Tissue Tumors

Soft Tissue NeoplasmSoft Tissue Sarcoma2 more

A retrospective evaluation of soft tissue tumors that have undergone core needle biopsy with US guidance (US-CNB)

Completed2 enrollment criteria

Patient Directed Intervention to Improve the Quality of Life for Patients With Soft Tissue Sarcoma...

Soft Tissue Sarcoma

The primary objective of the study is to compare quality of life (QoL) between patients suffering from soft tissue sarcoma, receiving a multidimensional intervention with those receiving standard treatment.

Completed17 enrollment criteria

Assessment of MGMT Promoter Methylation in Advanced Ewing Sarcoma Treated With Temozolomide and...

Ewing Sarcoma Family of Tumors

This is a biological study in patients with advanced Ewing Sarcoma who received, according, clinical practice, temozolomide and irinotecan The O6-methylguanine-DNA methyltransferase (MGMT) methylation status, will be correlated with the disease clinical data and with the disease response

Completed5 enrollment criteria

Development of Serologic Assays for Human Herpes Virus-8

Kaposi SarcomaHIV Infection

Dr. Burbelo and colleagues have developed a technique for rapidly and quantitatively detecting antibody responses in sera to a variety of pathogens using recombinant proteins. We would like to apply this technique to develop an assay for detecting antibodies to HHV-8 (KSHV, the etiologic agents of Kaposi's sarcoma, an AIDS-defining condition). We initially plan to examine samples from patients with Kaposi's sarcoma, since all those patients are almost certainly infected with HHV-8. We are thus using samples from patients with previously diagnosed Kaposi's sarcoma. The samples in question are stored at the NCI FCRF repository operated by SAIC Frederick or in Rockville, MD.

Completed1 enrollment criteria

Seroprevalence of Kaposi's Sarcoma Herpes Virus in the United States

Kaposi's SarcomaHerpesviridae Infection

This study will investigate patterns of Kaposi's sarcoma herpes virus (KSHV) in the United States and its potential impact on the U.S. population. KSHV is a newly discovered virus that is strongly associated with Kaposi's sarcoma and primary effusion lymphoma. The high prevalence of KS and KSHV among HIV-infected homosexual men suggests sexual contact as a primary mode of transmission. Reports of non-sexual transmission in parts of Africa and the Mediterranean where Kaposi's sarcoma is endemic, and the identification of viral DNA in saliva and other bodily fluids, however, indicate the virus is also transmitted non-sexually. This study will: Compare the prevalence of KSHV among different demographic groups in the United States Examine the association between KSHV and high risk behaviors such as drug use (marijuana and cocaine), sexual behavior (age at first sexual intercourse and number of sexual partners), and medical risk factors (herpes simplex virus II, hepatitis B and hepatitis C) Estimate the prevalence of KSHV in the United States. Data and blood samples for the study will be taken from the NHANES III survey. NHANES is a program of periodic surveys conducted by the Centers for Disease Control and Prevention's National Center for Health Statistics. The survey is designed to provide national estimates of health status for the United States non-institutionalized civilian population by means of household interviews, standardized physical examinations, and blood sample collection and testing. NHANES III-the seventh in a series of national examination studies-was conducted from 1988 to 1994. This study will use the HANES data to identify risks associated with a KSHV-positive blood test in the survey population. The study plans to include all 19,754 participants (67% of the 29,314 participants originally examined) for whom blood samples were collected and remain available.

Completed1 enrollment criteria

Perioperative Residual Adrenal Function After Extended Resection for Retroperitoneal Soft Tissue...

Adrenal; Functional DisturbanceRetroperitoneal Sarcoma1 more

Early recognition of adrenal function deficit in patients undergoing multivisceral surgery including adrenalectomy for primitive retroperitoneal sarcomas

Completed10 enrollment criteria

Chemotherapy-induced Necrosis in Ewing Sarcoma

Ewing Sarcoma of Bone

This is single institution cases series review of histological and clinical data

Completed6 enrollment criteria
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