Exploratory Trial to Assess the Functionality of an Integrated Call Center for the Digital Medicine...
SchizophreniaMajor Depressive Disorder1 moreThis study will assess the helpfulness of the integrated call center in optimizing use of the Digital Medicine System in adult subjects with Schizophrenia, Major Depressive Disorder, or Bipolar Disorder taking oral aripiprazole.
Psychoeducation for Vietnamese Families With a Patient With Schizophrenia
SchizophreniaFamilies with a patient with schizophrenia and the patient are randomly assigned to receive either a 3 session psychoeducation program, or no psychoeducation. Other treatment for schizophrenia and other mental illness are provided as usual.
Study of Repetitive Transcranial Magnetic Stimulation in the Treatment of Cognitive Impairment in...
SchizophreniaExploration of repetitive transcranial magnetic stimulation(rTMS)on working memory and cognitive impairment symptoms of schizophrenia treatment and mechanism. Analysis of high-frequency repetitive transcranial magnetic stimulation stimulation to the improvement of negative symptoms and psychotic symptoms.
A Safety, Tolerability, PK and PD Study of Multiple Oral Doses of SKL15508 in Subjects With Stable...
SchizophreniaThis is a single-site, randomized, double-blind, placebo-controlled, multiple dose, flexible dosage range, PK and PD study of SKL15508 as monotherapy in subjects with stable schizophrenia.
Long-term Study of Asenapine in Participants With Residual Subtype, Receiving Multiple or/and High...
SchizophreniaThis is a multi-site, open-label fixed-flexible dose long-term study of asenapine in participants with schizophrenia. Participants in this study consist of schizophrenia with residual subtype or receiving high dose/multiple antipsychotic drugs, treatment refractory, or elderly participants with schizophrenia. The treatment period is up to 52 weeks.
Neural Oscillations as Genetic and Functional Biomarkers in Normal and Disease States
SchizophreniaSchizoaffective Disorder1 moreThe principle aim of the project is to analyze brain electrical activity and genetic information that will help identify the nature and cause of the disease schizophrenia. This effort should lay the groundwork for future treatment in schizophrenic patients.
Multifamily Psychoeducation and Cognitive Remediation for Recent-Onset Psychosis
Recent-Onset PsychosisSchizophrenia4 moreThe goal of this study is to determine whether pairing multifamily group psychoeducation with cognitive remediation may facilitate improved outcomes among individuals with recent-onset psychosis.
Efficacy and Safety of SEROQUEL Extended Release (XR) in Acute Schizophrenia
SchizophreniaThe purpose of the study is to determine whether treatment with quetiapine XR (Seroquel XR) tablets for 3 weeks will improve their agitation when they have acute psychosis.
Oxytocin Treatment of Schizophrenia
ParanoiaSchizophrenia1 morePurpose: Test whether intranasal administration of the neuropeptide, oxytocin, improves social cognition, social functioning and decreases paranoia and other psychotic symptoms in schizophrenia. Participants: Up to 80 adults with schizophrenia for at least one year and with a high rating for paranoia. Procedures (methods): Oxytocin or placebo will be administered twice daily in an intranasal spray (6 insufflations/dose or 24 IU) for 6 weeks. Before, during and at the end of the trial, each subject will undergo social cognitive measures (primary outcomes) and psychiatric symptom ratings (secondary outcomes).
Cannabidiol Treatment of Cognitive Dysfunction in Schizophrenia
SchizophreniaSchizoaffective DisorderThis study is a six-week, randomized, placebo-controlled, fixed dose trial comparing cannabidiol Vs. placebo added to a stable dose of antipsychotic medications in patients diagnosed with schizophrenia.