
Study of Repetitive Transcranial Magnetic Stimulation in the Treatment of Cognitive Impairment in...
SchizophreniaExploration of repetitive transcranial magnetic stimulation(rTMS)on working memory and cognitive impairment symptoms of schizophrenia treatment and mechanism. Analysis of high-frequency repetitive transcranial magnetic stimulation stimulation to the improvement of negative symptoms and psychotic symptoms.

A Safety, Tolerability, PK and PD Study of Multiple Oral Doses of SKL15508 in Subjects With Stable...
SchizophreniaThis is a single-site, randomized, double-blind, placebo-controlled, multiple dose, flexible dosage range, PK and PD study of SKL15508 as monotherapy in subjects with stable schizophrenia.

Early Prediction of Clinical Response in Patients With Schizophrenia Treated by Paliperidone ER...
SchizophreniaSchizoaffective DisorderPaliperidone ER is a new psychotropic medication for schizophrenia treatment. The studies of 6-week acute treatment and 52-week maintenance treatment showed positive results in patients with schizophrenia and its clinical improvement may start at Day 4. Some second-generation antipsychotics have been found that using the first 2 weeks' treatment results to predict the fourth or sixth week's treatment response is acceptable. The primary aim of this study is to investigate: . whether the early prediction model used in other atypicals could also be applied in paliperidone ER. . The changes of metabolic parameters and pharmacokinetics after paliperidone ER treatment in this study

Olanzapine Pamoate Depot Versus Oral Olanzapine on Treatment Outcomes in Outpatients With Schizophrenia...
SchizophreniaTo compare the health outcome of patients with schizophrenia, who are at risk for relapse, when treated with a long acting injection form of olanzapine versus treatment with oral olanzapine.

A Study of the Cataractogenic Potential of Seroquel and Risperdal in the Treatment of Participants...
SchizophreniaSchizoaffective DisorderThis Phase IV, randomized, parallel-group study is designed to evaluate the cataractogenic potential of quetiapine fumarate (SEROQUEL) compared with that of a putative non-cataractogenic antipsychotic medication risperidone (RISPERDAL). This study is being conducted to fulfill the SEROQUEL Phase IV commitment regarding evaluation of cataractogenic potential.

Comparing the Effect of Under the Tongue Olanzapine Versus Swallowed Olanzapine on Body Mass Index...
SchizophreniaSchizoaffective Disorder1 moreThis study is testing if under the tongue olanzapine for schizophrenia, related psychosis, schizoaffective disorder or bipolar disorder will have less weight gain than olanzapine that is swallowed, in patients who are already gaining weight on olanzapine.

Efficacy Study of Early Onset of Antipsychotic Drug Action in Schizophrenia
SchizophreniaSchizoaffective Disorder1 moreThe current study has been designed to address the significance of early onset of response prospectively in patients treated with an atypical antipsychotic.

5HT3 Antagonism and Auditory Gating in Schizophrenia
SchizophreniaThe target groups in this study are brain waves and neurotransmitters (chemical messengers) in the brain. Subjects with diagnosed with schizophrenia will be studied. The study will help understand more about normal brain functioning and how that functioning differs in people with schizophrenia. Another purpose of this study is to determine how the altered brain functioning in schizophrenia contributes the symptoms found in the illness.

Olanzapine Versus An Active Comparator in the Treatment of Schizophrenia
SchizophreniaThe purpose of this study is to determine how Olanzapine compares to an active comparator in the treatment of schizophrenia

To Evaluate the Impact of Treatment Interruption on Re-initiation of Bifeprunox
SchizophreniaSchizoaffective DisorderThe purpose of this study is to investigate a safe treatment interruption interval(s) for re-initiation of bifeprunox at a therapeutic dose. The study duration is approximately 7 to 10 weeks.