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Active clinical trials for "Sleep Disorders, Circadian Rhythm"

Results 21-30 of 112

Skeletal Response to Simulated Night Shift

OsteoporosisCircadian Rhythm Sleep Disorder1 more

This small intervention study will determine if simulated short-term night shift work (NSW) negatively alters bone metabolism. The specific aim of the study is to determine if NSW acutely uncouples bone turnover markers (BTMs), if sympathetic tone is a mechanism for this disruption and if a resumption of a normal sleep/wake pattern reverses BTM uncoupling. Our hypothesis is that NSW will reversibly uncouple BTMs via increased sympathetic nervous system (SNS) tone.

Recruiting34 enrollment criteria

Factors Associated With Infant Circadian Rhythm, Growth, and Temperament

Circadian Rhythm Sleep DisorderJet Lag Type

The goal of this observational study is to learn about the role of modifiable factors affecting infant circadian rhythm so that recommendations can be made for better health outcomes for the mother and infant. The main questions it aims to answer are: What is the association of prenatal and postnatal maternal circadian clock with infant's circadian clock at 3 months? What is the association of birth outcomes, maternal factors, and environmental factors with infant circadian clock at 3 months? What is the role of infant circadian clock on infant growth and temperament at 6 months of age? Participants will complete a set of questionnaires and provide saliva samples during third trimester of pregnancy and at 3 months after birth of infant.

Recruiting8 enrollment criteria

Validating the Use of a Subjectively Reported Sleep Vital Sign

Obstructive Sleep Apnea (OSA)Insomnia3 more

Sleep disorders are commonly under-recognized in the primary care setting and available screening tools are often are limited. The study inestigators hypothesize that the use of a novel subjective sleep vital sign (VS) will improve recognition of patients with sleep disorders and can be utilized to track outcomes to sleep therapy.

Active3 enrollment criteria

Facilitating Adjustment to Simulated Jet Lag

Circadian Rhythm Sleep DisorderJet Lag Type

The aims of this study are to compare 3 different treatments for circadian adjustment to a laboratory protocol which will mimic westward air travel across 8 time zones. One treatment will involve simply following the new schedule for 3 days. Another treatment will also involve exposure to bright light for 1 hour per day. A third treatment will involve exposure to bright light + exercise for 1 hour per day + consuming a melatonin tablet. Adjustment to the shifted schedule will be assessed by comparing measures of sleep, mood, mental performance, physical performance, and timing of melatonin across the 3 treatment conditions.

Recruiting3 enrollment criteria

Optimizing Sleep Health in Nurses

Circadian Rhythm Sleep-Wake DisordersShift Work Type1 more

The aim of the proposed study is to pilot test two behavioral sleep intervention strategies for improving insomnia among night shift working nurses.

Not yet recruiting12 enrollment criteria

Sleep and Circadian Treatments for Shift Workers

Shift-Work Sleep DisorderShift-Work Related Sleep Disturbance

There are three components to this study: a Field Trial, a Shift Worker Survey, and Focus Groups. The Investigators will study the effectiveness, feasibility, and acceptability of an 8-h sleep intervention in older night workers in an operational environment. The overall goal of the Field Trial is to minimize sleep deficiency and negative outcomes resulting from that, including sleepiness and performance impairments during night shift work. The Shift Worker Survey is designed to understand some of the demographic and operational factors that enable or inhibit the ability of individual shift workers to adopt this intervention. The Focus Groups are designed to glean in-depth information from older shift workers who indicate that they are unable or unwilling to adopt an 8-h sleep timing intervention. Understanding these factors will assist in refining and targeting the intervention to those individuals who will be most likely to benefit from the intervention sleep timing strategy.

Active9 enrollment criteria

THRIVE Feasibility Trial

Surgery--ComplicationsAnesthesia Complication13 more

To evaluate the feasibility of a pragmatic, large scale, comparative effectiveness, randomized evaluation of patient experience of intravenous propofol versus inhaled volatile anesthesia.

Active10 enrollment criteria

Feasibility Pilot of Bright Light in the Intensive Care Unit

Circadian Rhythm Sleep DisorderUnspecified

To evaluate the feasibility of providing daytime bright light in the ICU in a pilot randomized controlled trial.

Enrolling by invitation16 enrollment criteria

Effect of Night Float Call on Sleep and Activity Patterns Among Anesthesia Residents

Sleep DisorderShift Work2 more

With increasing awareness about physician fatigue and its effect on patient safety, residency programs are increasingly transitioning to a night float call system. In other industries, multiple night shifts in a row can cause a disruption in the circadian rhythm, sleep debt, shift work disorder, that is related to chronic medical conditions such as obesity and cardiovascular disease. We will evaluate the effect of different call structures on resident activity, sleep and self reported measures of wellness using a commercially available Fitbit device.

Enrolling by invitation2 enrollment criteria

Does Fatigue Coaching Improve Functioning and Fatigue in Resident Night Shifts

FatigueShift Work Type Circadian Rhythm Sleep Disorder

Emergency Medicine (EM) requires 24/7 staff coverage resulting in healthcare workers' circadian rhythm disruptions that impair clinical and cognitive performance, physical recovery, and contribute to burnout. Multiple well-being surveys continue to highlight EM's challenges with sleep impairment due to the nature of the specialty. Despite evidence that lifestyle strategies effectively optimize performance and recovery, EM residents have variable lifestyle choices to prepare for overnight shifts. This prospective randomized controlled trial will examine whether a pre-shift personalized fatigue-mitigation lifestyle coaching (PFMLC) for EM residents on overnight shifts minimizes the effects of circadian rhythm disruptions on performance and recovery compared to those who receive one-time passive information on lifestyle practices. All participants will receive lifestyle strategy materials on fatigue mitigation to improve performance. Residents' self-reported and biometric data will inform PFMLC in the active arm. Performance and recovery from night shifts will be assessed by changes in sleep, heart rate variability, readiness/recovery, alertness, cognitive performance, and mental health using Fitbit and validated measures.

Not yet recruiting7 enrollment criteria
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