
Post-trial Access Program of Idursulfase-IT Along With Elaprase in Children With Hunter Syndrome...
Hunter SyndromeThis post-trial access program is to allow continued access for people who participated and are benefitting from treatment on the HGT-HIT-046 (NCT01506141) or SHP609-302 (NCT02412787) studies, which will be closed down. Idursulfase-IT also known as TAK-609, is a medicine to help treat Hunter Syndrome and issues with remembering, learning new things, and concentrating, also called cognitive impairment.

A Treatment Investigational New Drug (tIND) Program of Tegaserod in Women With Irritable Bowel Syndrome...
Irritable Bowel Syndrome With ConstipationChronic Idiopathic ConstipationTo provide tegaserod to eligible women adult patients who did not have satisfactory improvement of their irritable bowel syndrome with constipation (IBS-C) or chronic idiopathic constipation (CIC) symptoms with other available treatment(s) and / or patients who had satisfactory improvement of their symptoms with prior tegaserod treatment for IBS-C or CIC.

Compassionate Use Protocol for the Treatment of Autoinflammatory Syndromes
Chronic Atypical Neutrophilic Dermatosis With Lipodystrophy and Elevated Temperature (CANDLE)Juvenile Dermatomyositis (JDM)2 moreThe Requesting Physician/Investigator contacts Lilly when, based on their medical opinion, a patient meets the criteria for inclusion in the expanded access program.

Saliva Cortisol Measurement as a Screening Test for Suspicious Cushings Syndrome in Children.
Cushings SyndromeCortisol overproduction ( Cushings syndrome) is a condition where the patient have a special fat distribution, with accumulation of fat around the abdomen and in the neck, with thinner limbs and weak musculature. The condition can be difficult to separate from adipositas in general. Screening for hypercortisolism in adults has been easier the last years, because we can measure free cortisol in saliva samples at late night. In children we still dont have reference ranges for saliva cortisol in children, so the screening is still troublesome, based on Collection of 24-hour urine.The meaning of this study is to establish reference ranges for saliva cortisol, and evaluate in a cohort with adipose children if screening with saliva cortisol is sensitive and specific enough to be the New screening test for hypercortisolism in children too.

Microbiota Community of Irritable Bowel Syndrome in Episodes and Remission Phase
Irritable Bowel SyndromeAnalyze microbiota community of irritable bowel syndrome in episodes phase and remission phase.

Clinical Study to Validate the Use of a New Point of Care Troponin I Test
Acute Coronary SyndromeThis trial is designed as a prospective, multi-center, observational study of "all-comers" eligible adult subjects presenting to participating emergency departments with symptoms suggestive of acute coronary syndrome (ACS)

The Monocyte Subsets in Obese Patients With and Without Metabolic Syndrome
ObesityMetabolic SyndromeObesity is associated with a chronic low-grade inflammation characterized by macrophage infiltration in adipose tissue that induces insulin resistance and the appearance of metabolic syndrome (MS). The aim of the study was the investigation of whether circulating monocyte subsets are differentially regulated in MS.

Use of Novel Plasma and Urinary Biomarkers to Predict the Development of Hepatorenal Syndrome in...
Hepatorenal SyndromeThis study investigated the use of novel plasma and urinary biomarkers to predicte the development of hepatorenal syndrome in patients with advanced cirrhosis. The biomarkers investigated include plasma cystatin C, plasma NGAL, plasma NAG, plasma IL-18, plasma ADMA, plasma BTP, urinary KIM-1 and urinary LFABP. These biomarkers will be checked in advanced cirrhotic patients who have or have not developed hepatorenal syndrome and compared between the two groups. These biomarkers will also be correlated with the occurence of hepatorenal syndrome.

Women With Polycystic Ovary Syndrome (PCOS)
Polycystic Ovary SyndromeMetabolic profile in women of different body composition with polycystic ovary syndrome.

Clinical Decision Support System to Define 30 Day Adverse Clinical Events for Emergency Department...
Acute Coronary SyndromeClinical Decision Support SystemAcute coronary syndromes are among main complains for patients presenting to emergency department. Risk classification systems are used to classify patients to appropriate risks and help physicians manage diagnosis strategies and treatments. Purpose of this study is to develop a clinical decision support system for patients presenting to emergency department with the help of statistical machine learning.