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Active clinical trials for "Pelvic Organ Prolapse"

Results 51-60 of 416

Early Safety of Resection Recopy and Sacrocolpopexy

Constipation by Outlet ObstructionPelvic Organ Prolapse1 more

Obstructive defecation syndrome (ODS) defines a disturbed defecation process frequently associated with pelvic organ prolapse (POP) in women. It substantially compromises quality of life and conservative treatment options are limited. In cases surgery is required the interventions are characterized by individual approaches. Laparoscopic resection rectopexy (L-RRP) combined with laparoscopic sacrocolpopexy (L-SCP) was established in an interdisciplinary setting.

Recruiting4 enrollment criteria

Postoperative Return to Sexual Activity

Sexual Function DisturbancesPelvic Organ Prolapse2 more

To determine if standardized counselling regarding first sexual encounter after pelvic reconstructive surgery for pelvic organ prolapse and / or urinary incontinence improves postoperative preparedness to return to sexual activity and sexual function.

Recruiting8 enrollment criteria

Long-term Evaluation of the Efficacy and Safety of Splentis for the Treatment of Primary Apical...

Pelvic Organ Prolapse

This prospective, multi center cohort trial aims to evaluate the efficacy and safety of hysteropexy using Splentis via the vaginal route in primary uterine prolapse

Recruiting11 enrollment criteria

Lateral Suspension Versus Sacral Colpopexy POP

Pelvic Organ Prolapse

The aim of the study will be to compare the SCP and LLS in the management of apical prolapse at 6 weeks, 6 months, 1 year and yearly up to 2 years with the null hypothesis being that no significant differences existed between the two surgical procedures.

Not yet recruiting10 enrollment criteria

Pelvic Ultrasound Pessary Study: Changes in Pelvic Anatomy After Placing a Pessary

Pelvic Organ Prolapse

In the past, the impact of pessaries was mostly assessed by questionnaires on Quality of Life (QoL) and sexual dysfunction. This research project primarily aims to objectify the effects of the currently available pessaries in a different way. To accomplish this, the investigators choose transperineal ultrasound and uroflowmetry. Additionally, this project aims to describe the impact of pessaries on the symptoms and QoL.

Recruiting9 enrollment criteria

Self-management Pessary Project

Pelvic Organ Prolapse

The goal of this multicenter observational study is to study self-management of pessary therapy in patients with pelvic organ prolapse. The primary question it aims to answer is: • how many patients succeed learning self-management if offered a standardized training? Secondary outcomes are: how many patients are willing to learn self-management? what patient factors contribute to successfully learning self-management and willingness to self-manage? how satisfied are patients with pessary therapy and self-management? the occurrence of side-effects continuation and quitting of pessary therapy and self-management cross-over to surgery number of visits to doctor because of pessary therapy healthcare costs Participants will be asked to fill in questionnaires three times during the study (upon inclusion, 6 weeks and 12 months after starting self-management or after starting pessary therapy with a correctly fitting pessary). Researchers will compare the self-managing patient to the non-self-managing patients.

Recruiting5 enrollment criteria

Superiority of Perineoplasty as Concomitant Surgical Procedure During Pelvic Organ Prolapse Repair...

Pelvic Organ Prolapse

The goal of this study is to evaluate whether adding perineoplasty is, in comparison to performing vaginal prolapse surgery without adding perineoplasty, superior with respect to efficacy and cost-effectiveness and non-inferior with respect to morbidity, in patients undergoing vaginal surgical correction of pelvic organ prolapse at 24 months after surgery.

Recruiting8 enrollment criteria

Pessary Experience Study

Pelvic Organ ProlapseStress Urinary Incontinence

Pessaries are silicone devices inserted into the vagina for treatment of pelvic organ prolapse or stress urinary incontinence. They are adequate treatment options for patients who are poor surgical candidates, those who decline surgical intervention, or as a temporizing measure in those ultimately planning surgery. Most studies suggest that about 75% of patients are able to be successfully fit with a pessary, but about 50% discontinue pessary use within 12 months of initiation. The purpose of this study is to determine why pessaries are discontinued.

Recruiting12 enrollment criteria

Post-market Clinical Follow-up of the SRS Implant

Pelvic Organ Prolapse

National, multicentre observational study on surgical reconstruction of the anterior and apical compartment of the pelvic floor with an SRS implant

Recruiting9 enrollment criteria

Efficacy/Safety of Urogynecology Synthetic Mesh Surgery

Pelvic Organ ProlapseStage III and IV High Grade Pelvic Organ Prolapse

This is a retrospective cohort study, aiming at analyzing the efficacy and safety of mesh surgery in pelvic organ prolapse. The synthetic mesh for pelvic organ prolapse include transvaginal mesh or laparotomy, laparoscope, or robotic-assisted laparoscopic sacrocolpopexy with mesh augmentation. The investigators would like to evaluate the efficacy and safety, such as recurrence rates and complication rates for women who underwent urogynecology mesh surgery.

Recruiting5 enrollment criteria
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