search

Active clinical trials for "Vascular Diseases"

Results 301-310 of 958

TX2® Low Profile TAA Endovascular Graft

Aortic AneurysmPenetrating Ulcer1 more

The Zenith® TX2® Low Profile TAA Endovascular Graft study is a clinical trial approved by US FDA to evaluate the safety and effectiveness of the Zenith® TX2® Low Profile TAA Endovascular Graft indicated for the treatment of patients with aneurysms/ulcers of the descending thoracic aorta having vessel structure suitable for repair.

Completed9 enrollment criteria

Counseling Older Adults to Control Hypertension

HypertensionVascular Diseases1 more

This study will evaluate the effect of a senior center-based comprehensive therapeutic lifestyle intervention delivered through group-based counseling and motivational interviewing (MINT-TLC) among 250 hypertensive African American or Latino seniors age 60 and older in a randomized control trial.

Completed9 enrollment criteria

Safety Study of Bone Marrow Cell Concentrate Prepared Using the Magellan System to Treat Critical...

Critical Limb Ischemia (CLI)Peripheral Vascular Disease (PVD)

The purpose of this study is to evaluate the safety of administration of marrow-derived autologous hematopoietic stem cells (HSC) concentrate and platelet-rich plasma (PRP) gel for the treatment of Critical Limb Ischemia (CLI).

Completed32 enrollment criteria

Intra-arterial Stem Cell Therapy for Patients With Chronic Limb Ischemia (CLI)

Peripheral Vascular DiseasesArterial Occlusive Diseases3 more

The purposes of this study are to determine whether intra-arterial injection of autologous stem cells is effective in the treatment of chronic limb ischemia (CLI), to characterize stem cell dysfunction in patients with CLI, and to relate the stem cell function with clinical outcome.

Completed11 enrollment criteria

LEVANT I, The Lutonix Paclitaxel-Coated Balloon for the Prevention of Femoropopliteal Restenosis...

AtherosclerosisVascular Disease1 more

The purpose of the study is to assess the safety and efficacy of the Lutonix Catheter for treatment of stenosis of the femoropopliteal arteries by direct comparison to standard balloon angioplasty.

Completed25 enrollment criteria

Evaluating Two Exercise Training Programs to Reduce Leg Pain in People With Peripheral Arterial...

Intermittent ClaudicationPeripheral Vascular Diseases

Peripheral arterial disease (PAD) is a disorder that affects more than 8 million people in the United States. As a result of decreased blood flow to the legs, people with PAD may experience leg pain and difficulty with walking. This study will examine the effectiveness of two exercise programs-a treadmill walking program and an aerobic arm exercise program-at increasing walking distance and decreasing leg pain in people with PAD.

Completed10 enrollment criteria

Study of Hepatocyte Growth Factor (HGF) Via Plasmid Vector to Improve Perfusion in Critical Limb...

Arterial Occlusive DiseasePeripheral Vascular Disease2 more

The objective of this study is to test the hypothesis that AMG0001 treatment is safe and induces angiogenesis as detected by improved wound healing, reduction in amputation, improved pain at rest and hemodynamic measurement and to assess the effectiveness of the administrative method.

Completed29 enrollment criteria

Mirror Trial - Follow-Up Management of Peripheral Arterial Intervention With Clopidogrel

Peripheral Vascular Diseases

The Mirror Study is a randomized, double-blinded mono-centre trial the access the periinterventinal and postinterventional administration of clopidogrel in patients with peripheral vascular disease.

Completed5 enrollment criteria

Study of HGF Via Plasmid Vector to Improve Perfusion in Critical Limb Ischemia

Arterial Occlusive DiseasePeripheral Vascular Disease1 more

The primary purpose of this study was to assess the overall safety of different dose regimens of AMG0001 (HGF transferred via plasmid vector) as well as evaluate the improvement of blood perfusion in subjects with critical limb ischemia (CLI). This study also evaluated the improvement in wound healing without adverse effects on the quality of life, as well as the potential reduction of amputation, mortality and rest pain in the CLI population.

Completed19 enrollment criteria

Effect of Niacin ER/Lovastatin on Peak Walking Time & Claudication Onset Time in Patients With Intermittent...

Intermittent ClaudicationPeripheral Vascular Disease

The purpose of this study is to evaluate if Niacin ER/Lovastatin, at two different doses, compared to diet control (this group will receive a tablet containing 50 mg. of immediate-release niacin) is a safe and effective medicine in subjects with leg pain caused by a narrowing of their leg arteries, a condition called intermittent claudication. At least 366 subjects with leg pain caused by a narrowing of their leg arteries will participate in this study. Niacin ER/Lovastatin is a combination of two FDA (United States Food and Drug Administration) approved cholesterol modifying medications: Niaspan® (extended-release niacin) and lovastatin, a statin (the same medicine found in Mevacor®). Niacin ER/Lovastatin was approved by the FDA under the name of Advicor® for use in the treatment of elevated cholesterol. The use of Niacin ER/Lovastatin in the treatment of peripheral arterial disease and symptomatic relief of intermittent claudication is considered investigational. An investigational use is one that is not approved by the FDA.

Completed11 enrollment criteria
1...303132...96

Need Help? Contact our team!


We'll reach out to this number within 24 hrs