Diagnosis of Hemangiomas and Vascular Malformations
HemangiomasVascular Malformations4 moreTo develop a non-invasive, simple and affordable, measurement technique to differentiate hemangiomas from subtypes of VMS. The purpose of this study is to determine the best office based diagnositc instrument for differentiating the subtype of vascular lesions. The instrument must be simple and affordable so it can be used by primary car physicians in the doctor office. The procedure will be based on non-invasive and unharmful measurements that will be compared to the diagnosis from specialized physicians in this field and the final pathology.
Estimation of the Placental Volume by 3D Ultrasound at 12, 16 and 22 Weeks : Relation With Growth...
Placenta Vascular MalformationPregnancy complications called PVP are mainly responsible for perinatal mortality. In these cases, the placenta is smaller and often the centre of thrombotic lesions. The estimation of the placenta volume by 3D ultrasound coupled with growth factors and D-Dimers measures could improve the understanding of these pathologies to optimize their detection.
Bone Health in Patients With Overgrowth
Bone Mineral DensityVascular MalformationsThe goal of this study is to determine whether or not patients with overgrowth syndromes have decreased bone density.
The Management of Postoperative Craniotomy Pain in Pediatric Patients
Post Craniotomy SurgeryCancer3 moreThe purpose of this prospective, clinical observational trial is to assess the incidence of pain (and analgesia), methods of pain assessment (and by whom), prescribed analgesics, methods of analgesic delivery, and patient/parent satisfaction in patients undergoing craniotomy surgery at three major children's hospitals (Boston Children's Hospital, Children's Hospital of Philadelphia, The Children's Center Johns Hopkins Hospital) in the United States.
Normal Saline Vrs Balanced i.v. Fluids in Neurosurgery
Benign NeoplasmsVascular Malformations1 moreThe purpose of this study was to investigate whether the balanced fluids therapy change plasma osmolality in neurosurgical procedures due to brain tumors, meningeomas and arterio-venous malformation.
Assessing the Effects of Air-cooling on Capillary Malformations
Capillary MalformationLaser1 moreThe purpose of this observational study is to ascertain the effects of cutaneous air cooling on vessel diameter within Capillary Malformations (CM).
The Efficacy and Safety of Different Phlebotonic Drugs in Children With Venous Malformations
Drug EffectChildren3 moreThe aim of this study is to evaluate the efficacy and safety of different phlebotonic drugs in children and to assess patient satisfaction after treatment.
Expanded Access to Provide ARQ 092 for the Treatment of Overgrowth Diseases and/or Vascular Anomalies...
Proteus SyndromePIK3CA-Related Overgrowth Spectrum (PROS)1 moreARQ 092 is being investigated for patients with overgrowth diseases and/or vascular anomalies with genetic alterations of the PI3K/AKT pathway and may be available for patients who are ineligible for an ongoing ARQ 092 clinical trial or have other considerations that prevent access to ARQ 092 through an existing clinical trial.
Imaging Lymphatic Function in Normal Subjects and in Persons With Lymphatic Disorders
LymphedemaLymphatic Disorders4 moreThe purpose of this study is to demonstrate the feasibility of near-infrared fluorescence imaging in subjects with acquired or hereditary lymphedema, in subjects with lipidema and other lymphovascular disorders and in normal health subjects; in order to attempt to correlate imaging phenotype(s) with genotype(s).