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Active clinical trials for "Varicose Ulcer"

Results 41-50 of 303

Fat Grafting in Reducing Recurrence in Patients With Healed Venous Ulcers A Prospective Randomised...

Varicose Ulcer

In this study, investigators aim to use fat grafting in patients with previously healed venous ulcers to study its role on increasing skin thickness and reconstructing skin layers which was damaged by venous hypertension and determine its impact on reducing recurrence rates at 1 year

Recruiting10 enrollment criteria

Wound Healing Endpoint and Recurrence

Chronic WoundBurn Wound5 more

This prospective pilot study is to enroll patients with clinically-defined infected wounds. Patients enrolled in the study will be followed for 16 weeks for wound closure (Phase A), and will then begin Phase B. 265 clinically diagnosed infected burn or chronic wound patients will be recruited for this study in Phase A. Based on the expectation that 89% of these wounds will heal within 16 weeks of enrollment, 234 of these patients will continue with the study for Phase B.

Recruiting24 enrollment criteria

A Clinical Investigation to Follow the Progress of Exuding Chronic Venous Leg Ulcers Using a Non-Bordered...

WoundsWound of Skin2 more

The goal of this clinical trial to follow the progress of wounds in those with chronic venous leg ulcers while using a non-bordered foam dressing. The main objective is to follow the progress of these wounds over time from initial visit to each follow-up visit. Participants will be asked to wear the dressing for up to 6 weeks of treatment or until healed, changed at every one-week interval.

Recruiting12 enrollment criteria

Comparison of the Effects of Lower Limb Immobilisation With Cast and Orthosis

Venous StasisDeep Venous Thrombosis

In this study we are going to measure the blood flow in the lower limbs under cast immobilisation and also under mobilisation with an orthosis. The aim is to evaluate how the aforementioned modalities affect the blood flow and also to compare between the two.

Recruiting4 enrollment criteria

A Research Study to Evaluate the Safety and Potential Efficacy of ON101 Cream for the Treatment...

Venous Leg Ulcers (VLU)

A Research Study to evaluate the safety and potential efficacy of ON101 cream for the treatment of venous leg ulcers.The objectives of the study are to determine the safety and to explore the potential efficacy of ON101 cream in patients with venous leg ulcers.

Recruiting33 enrollment criteria

A Clinical Investigation to Follow the Progress of Exuding Chronic Wounds Using Mepilex® Up as the...

WoundsWound of Skin4 more

The goal of this clinical trial is to follow the progress of wounds in those with venous leg ulcers and diabetic foot ulcers while using an absorbent dressing called Mepilex Up. The main objective is to follow the progress of these wounds over time from initial visit to each follow-up visit. Participants will be asked to wear Mepilex Up dressing for up to 6 weeks of treatment or until healed, changed at every one-week interval.

Recruiting12 enrollment criteria

Developing Strategies for Effective Debridement in Patients for Venous Leg Ulcers

Venous Leg Ulcer

The goal of this project is to use genomic profiling, candidate genes and proteins to develop guided surgical debridement to improve healing in chronic non-healing venous leg ulcers (VLUs) and to test the efficacy of this approach.

Recruiting25 enrollment criteria

Open Label Single Arm Proof of Concept Trial to Evaluate the Efficacy and Safety of Cytori Celution...

Venous Leg UlcerAutologous Adipose Stromal Vascular Fraction2 more

To evaluate the efficacy and safety of Cytori Celution System in Hungarian patients with chronic non-healing venous leg ulcers.

Recruiting29 enrollment criteria

A Multicentre European Study to Evaluate Granulox® Used in the Treatment Pathway of Predominantly...

Venous Leg Ulcer

The investigation is designed as an open label, randomized, prospective, assessor blinded, multi centre investigation. 254 evaluable subjects will be randomized to either standard of care group or standard of care with Granulox added as an adjunct therapy in predominantly venous leg ulcer subjects. Standard of care wound management will be completed, including wound cleansing, debridement if necessary and application of a suitable dressing and compression system until complete wound closure. The study will be divided into two phases. Firstly, a two week run-in period to ensure compliance to compression therapy followed by a 20 weeks treatment period starting with randomization and allocation of treatment.

Active27 enrollment criteria

Enhanced Ultrasound Treatment of Chronic Wounds With Monitoring of Healing and Quality of Life Outcomes...

Diabetic Foot UlcerVenous Ulcer

The purpose of this study is to evaluate the effect of low frequency, low intensity ultrasound treatment on wound healing and health-related quality of life with a randomized clinical trial of patients with venous ulcers or diabetic ulcers.

Active17 enrollment criteria
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